Relação entre o teste de equilíbrio peritoneal e alterações no peso corpóreo de pacientes em diálise peritoneal

• Autor(a) principal: Rocha, Sulene Rosa da
• Data de Publicação: 2012
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Biblioteca Digital de Teses e Dissertações da PUC_RS
• Texto Completo: http://tede2.pucrs.br/tede2/handle/tede/1702
• topic: MEDICINA; NEFROLOGIA; DIÁLISE PERITONEAL; GANHO DE PESO; COMPOSIÇÃO CORPORAL; TECIDO ADIPOSO; CNPQ::CIENCIAS DA SAUDE::MEDICINA

Objective: The aim of this study was to evaluate the relationship between body weight gain and small solute transport by the peritoneum Methods: A retrospective review was conducted of the records from 50 patients over the age of 18 years, all of whom had undergone peritoneal dialysis for at least one year. Weight changes were recorded at quarterly intervals until completion of one year of therapy and were subsequently compared with the categories of peritoneal transport. Biochemical markers including glucose, albumin and lipid profile were evaluated at the beginning of therapy and again one year later. Results: A significant effect of time on the mean body weight of the study participants was detected, as shown by the Repeated Measures Analysis of Variance. The final BMI mean was significantly higher than the initial. A significant reduction in serum albumin also occurred. However, no significant difference was found when comparing the weight change over the first year of treatment to the categories from the peritoneal equilibration test. Conclusion: This study was unable to demonstrate the existence of an association between the initial peritoneal membrane small solute transport with weight changes in patients undergoing peritoneal dialysis. The acknowledged multifactorial nature of obesity may be a possible explanation for our findings. The glucose uptake rate by the peritoneum does not seem to be responsible, therefore, it is necessary to search for factors linked to peritoneal dialysis that would have a greater influence on the observed alterations in nutritional status