Um estudo comparativo da micro e da macroestrutura de narrativas orais na lesão de hemisfério esquerdo e direito e sua relação com volumetria cerebral
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da PUC_RS |
Texto Completo: | http://tede2.pucrs.br/tede2/handle/tede/8382 |
Resumo: | This research aims to analyze the micro and macrostructure in the oral production of three narratives, produced from a sequence of pictures, comparing the performance of participants with right hemisphere damage (RHD) and participants with left hemisphere damage (LHD) with the performance of control groups. Furthermore, the linguistic analysis was related to data of memory constructs (working and semantic), reading and writing habits and brain volumetry. The research is divided into Study 1 and Study 2. For Study 1, 32 adult participants who suffered ischemic stroke were selected (with a minimum of four months before collection) to compose the experimental group – 16 participants in LHD and 16 participants in RHD aged between 50 to 79, with a minimum of two and maximum of 12 years of schooling; and 16 participants within the health control (CG), paired in age and schooling with the clinics. From these, 10 participants of each group – capable to perform magnetic resonance imaging exams – were selected to make part of Study 2, which relates data from neuropsychological and linguistic tasks to data from structural neuroimaging – known as Voxel-based morphometry (VBM). Inferential analysis in Study 1 showed that post-stroke writing and naming variables influenced significantly the performance in the micro and macrostructure, with the clinical group obtaining a statistically inferior result in the microstructure in relation to the CG. In relation to the macrostructure, there was also a significant correlation in the Digit span (working memory) in the three groups, but without statistical difference between the groups. In Study 2, LHD performance was significantly lower in the microstructure compared to RHD and CG. In the microstructure, in Study 2, the brain regions were grouped into four major components (CP). Thus, in the inferential analysis, all the main components of the brain areas (CP1, CP2, CP3 and CP4) showed a correlation with the microstructure variable, as well as significantly correlated post-stroke writing and naming variables. In the macrostructure, in Study 2, the variables that presented a statistically significant effect were GLH, writing habits after stroke, working memory and interaction between GLH variables and one of the main components of brain area (CP3). The parahippocampal area of the RH showed a correlation with CP3, which implies that this region significantly differentiates LHD from RHD in macrostructure processing. Thus, based on the analyzes and discussions proposed in the study, it was intended to contribute to the understanding of micro and macrostructure characterization in the production of oral narratives in right hemisphere and left hemisphere lesions and their correlation with cognitive constructs, more specifically of working memory and semantics and volume of brain areas involved. The work sought to advance in the discussion surrounding hemispheric specialization for the processing of oral discourse, especially of narratives, for the benefit of future research and clinical intervention. |
id |
P_RS_c5c0df469213571cc083cf609b7bee7e |
---|---|
oai_identifier_str |
oai:tede2.pucrs.br:tede/8382 |
network_acronym_str |
P_RS |
network_name_str |
Biblioteca Digital de Teses e Dissertações da PUC_RS |
repository_id_str |
|
spelling |
Hübner, Lilian Cristinehttp://lattes.cnpq.br/4814925793637987http://lattes.cnpq.br/0363765005528268Schneider, Fernanda2018-12-17T12:08:18Z2018-10-31http://tede2.pucrs.br/tede2/handle/tede/8382This research aims to analyze the micro and macrostructure in the oral production of three narratives, produced from a sequence of pictures, comparing the performance of participants with right hemisphere damage (RHD) and participants with left hemisphere damage (LHD) with the performance of control groups. Furthermore, the linguistic analysis was related to data of memory constructs (working and semantic), reading and writing habits and brain volumetry. The research is divided into Study 1 and Study 2. For Study 1, 32 adult participants who suffered ischemic stroke were selected (with a minimum of four months before collection) to compose the experimental group – 16 participants in LHD and 16 participants in RHD aged between 50 to 79, with a minimum of two and maximum of 12 years of schooling; and 16 participants within the health control (CG), paired in age and schooling with the clinics. From these, 10 participants of each group – capable to perform magnetic resonance imaging exams – were selected to make part of Study 2, which relates data from neuropsychological and linguistic tasks to data from structural neuroimaging – known as Voxel-based morphometry (VBM). Inferential analysis in Study 1 showed that post-stroke writing and naming variables influenced significantly the performance in the micro and macrostructure, with the clinical group obtaining a statistically inferior result in the microstructure in relation to the CG. In relation to the macrostructure, there was also a significant correlation in the Digit span (working memory) in the three groups, but without statistical difference between the groups. In Study 2, LHD performance was significantly lower in the microstructure compared to RHD and CG. In the microstructure, in Study 2, the brain regions were grouped into four major components (CP). Thus, in the inferential analysis, all the main components of the brain areas (CP1, CP2, CP3 and CP4) showed a correlation with the microstructure variable, as well as significantly correlated post-stroke writing and naming variables. In the macrostructure, in Study 2, the variables that presented a statistically significant effect were GLH, writing habits after stroke, working memory and interaction between GLH variables and one of the main components of brain area (CP3). The parahippocampal area of the RH showed a correlation with CP3, which implies that this region significantly differentiates LHD from RHD in macrostructure processing. Thus, based on the analyzes and discussions proposed in the study, it was intended to contribute to the understanding of micro and macrostructure characterization in the production of oral narratives in right hemisphere and left hemisphere lesions and their correlation with cognitive constructs, more specifically of working memory and semantics and volume of brain areas involved. The work sought to advance in the discussion surrounding hemispheric specialization for the processing of oral discourse, especially of narratives, for the benefit of future research and clinical intervention.A presente pesquisa teve como objetivo analisar o processamento da micro e da macroestrutura na produção oral de três narrativas, produzidas a partir de sequência de figuras, comparando o desempenho de participantes com lesão de hemisfério esquerdo (LHE) e participantes com lesão de hemisfério direito (LHD), com a de controles. Outrossim, a análise linguística foi relacionada a dados de construtos de memória (de trabalho e semântica), hábitos de leitura e escrita e de volumetria cerebral. A pesquisa foi dividida em Estudo 1 e Estudo 2. Para o Estudo 1, foram selecionados 32 participantes adultos que sofreram acidente vascular cerebral (AVC) isquêmico - 16 participantes no GLHE e 16 participantes no GLHD - entre 50 e 79 anos, com mínimo de 2 e máximo 12 anos de escolaridade; 16 participantes saudáveis controles (GC), pareados por idade e escolaridade com os clínicos. Desses, 10 participantes de cada grupo foram selecionados para fazerem parte do Estudo 2, em que se relacionaram os dados das tarefas neuropsicológicas e linguísticas a dados da neuroimagem estrutural de morfometria baseada em voxel (em inglês, Voxel-based morphometry - VBM). A análise inferencial mostrou, no Estudo 1, que as variáveis escrita pós-AVC e nomeação influenciaram de modo significativo o desempenho na micro e na macroestrutura com o grupo clínico obtendo resultado estatisticamente inferior na microestrutura em relação ao GC. Em relação à macroestrutura, houve uma correlação significativa também no Digit span (memória de trabalho) nos três grupos, porém sem diferença estatística entre os grupos. No Estudo 2, a performance do GLHE foi significativamente inferior na microestrutura em comparação com GLHD e GC. Na microestrutura do Estudo 2, as regiões cerebrais foram agrupadas em quatro componentes principais (CP). Assim, na análise inferencial, todos os componentes principais das áreas cerebrais (CP1, CP2, CP3 e CP4) apresentaram correlação com a variável microestrutura, assim como correlacionaram significativamente as variáveis escrita pósAVC e nomeação. Na macroestrutura, do Estudo 2, as variáveis que apresentaram efeito estatisticamente significativo foram GLHE, hábitos de escrita posteriores ao AVC, memória de trabalho e a interação entre as variáveis GLHE e um dos componentes principais de área cerebral (CP3). A área parahipocampal do HD demonstrou correlação com o CP3, o que implica afirmar que essa região diferencia significativamente o GLHE do GLHD quanto ao processamento da macroestrutura. Assim, a partir das análises e discussões propostas no estudo, pretendeu-se contribuir para a compreensão da caracterização da micro e da macroestrutura na produção de narrativas orais na lesão de HD e HE e sua correlação com construtos cognitivos, mais especificamente da memória de trabalho e semântica, e volume de áreas cerebrais implicadas. Procurou-se avançar na discussão sobre a especialização hemisférica para o processamento do discurso oral, em especial de narrativas, para benefício de pesquisas futuras e de intervenções clínicas.Submitted by PPG Letras (letraspg@pucrs.br) on 2018-12-13T10:48:35Z No. of bitstreams: 1 Fernanda_Schneider_VERSÃO FINAL 12_12.pdf: 2996710 bytes, checksum: 10f51d3b651bfbe650679cd5e4cd2155 (MD5)Approved for entry into archive by Sheila Dias (sheila.dias@pucrs.br) on 2018-12-17T11:56:24Z (GMT) No. of bitstreams: 1 Fernanda_Schneider_VERSÃO FINAL 12_12.pdf: 2996710 bytes, checksum: 10f51d3b651bfbe650679cd5e4cd2155 (MD5)Made available in DSpace on 2018-12-17T12:08:18Z (GMT). No. of bitstreams: 1 Fernanda_Schneider_VERSÃO FINAL 12_12.pdf: 2996710 bytes, checksum: 10f51d3b651bfbe650679cd5e4cd2155 (MD5) Previous issue date: 2018-10-31Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESapplication/pdfhttp://tede2.pucrs.br:80/tede2/retrieve/173735/TES_FERNANDA_SCHNEIDER_CONFIDENCIAL.pdf.jpghttp://tede2.pucrs.br:80/tede2/retrieve/179781/TES_FERNANDA_SCHNEIDER_COMPLETO.pdf.jpgporPontifícia Universidade Católica do Rio Grande do SulPrograma de Pós-Graduação em LetrasPUCRSBrasilEscola de HumanidadesProdução OralMicroestruturaMacroestruturaNarrativaMemória de TrabalhoMemória SemânticaAcidente Vascular CerebralVBMLINGUISTICA, LETRAS E ARTES::LETRASUm estudo comparativo da micro e da macroestrutura de narrativas orais na lesão de hemisfério esquerdo e direito e sua relação com volumetria cerebralinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisTrabalho será publicado como artigo ou livro24 meses17/12/2020407477848473845987500500500600-6557531471218110192-54094192628864980883590462550136975366info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da PUC_RSinstname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSORIGINALTES_FERNANDA_SCHNEIDER_COMPLETO.pdfTES_FERNANDA_SCHNEIDER_COMPLETO.pdfapplication/pdf2996710http://tede2.pucrs.br/tede2/bitstream/tede/8382/5/TES_FERNANDA_SCHNEIDER_COMPLETO.pdf10f51d3b651bfbe650679cd5e4cd2155MD55THUMBNAILTES_FERNANDA_SCHNEIDER_CONFIDENCIAL.pdf.jpgTES_FERNANDA_SCHNEIDER_CONFIDENCIAL.pdf.jpgimage/jpeg4088http://tede2.pucrs.br/tede2/bitstream/tede/8382/4/TES_FERNANDA_SCHNEIDER_CONFIDENCIAL.pdf.jpgb4c07015d16169056164f4c090fefadaMD54TES_FERNANDA_SCHNEIDER_COMPLETO.pdf.jpgTES_FERNANDA_SCHNEIDER_COMPLETO.pdf.jpgimage/jpeg5688http://tede2.pucrs.br/tede2/bitstream/tede/8382/7/TES_FERNANDA_SCHNEIDER_COMPLETO.pdf.jpgcd47395a87797569ac2f31f448637698MD57TEXTTES_FERNANDA_SCHNEIDER_CONFIDENCIAL.pdf.txtTES_FERNANDA_SCHNEIDER_CONFIDENCIAL.pdf.txttext/plain1785http://tede2.pucrs.br/tede2/bitstream/tede/8382/3/TES_FERNANDA_SCHNEIDER_CONFIDENCIAL.pdf.txt8d9eb552b1f6df45c163831dd89baf40MD53TES_FERNANDA_SCHNEIDER_COMPLETO.pdf.txtTES_FERNANDA_SCHNEIDER_COMPLETO.pdf.txttext/plain410056http://tede2.pucrs.br/tede2/bitstream/tede/8382/6/TES_FERNANDA_SCHNEIDER_COMPLETO.pdf.txte50aa2a60f09699d494e87719e8df5f2MD56LICENSElicense.txtlicense.txttext/plain; charset=utf-8590http://tede2.pucrs.br/tede2/bitstream/tede/8382/1/license.txt220e11f2d3ba5354f917c7035aadef24MD51tede/83822020-12-21 20:00:17.733oai:tede2.pucrs.br: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Biblioteca Digital de Teses e Dissertaçõeshttp://tede2.pucrs.br/tede2/PRIhttps://tede2.pucrs.br/oai/requestbiblioteca.central@pucrs.br||opendoar:2020-12-21T22:00:17Biblioteca Digital de Teses e Dissertações da PUC_RS - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false |
dc.title.por.fl_str_mv |
Um estudo comparativo da micro e da macroestrutura de narrativas orais na lesão de hemisfério esquerdo e direito e sua relação com volumetria cerebral |
title |
Um estudo comparativo da micro e da macroestrutura de narrativas orais na lesão de hemisfério esquerdo e direito e sua relação com volumetria cerebral |
spellingShingle |
Um estudo comparativo da micro e da macroestrutura de narrativas orais na lesão de hemisfério esquerdo e direito e sua relação com volumetria cerebral Schneider, Fernanda Produção Oral Microestrutura Macroestrutura Narrativa Memória de Trabalho Memória Semântica Acidente Vascular Cerebral VBM LINGUISTICA, LETRAS E ARTES::LETRAS |
title_short |
Um estudo comparativo da micro e da macroestrutura de narrativas orais na lesão de hemisfério esquerdo e direito e sua relação com volumetria cerebral |
title_full |
Um estudo comparativo da micro e da macroestrutura de narrativas orais na lesão de hemisfério esquerdo e direito e sua relação com volumetria cerebral |
title_fullStr |
Um estudo comparativo da micro e da macroestrutura de narrativas orais na lesão de hemisfério esquerdo e direito e sua relação com volumetria cerebral |
title_full_unstemmed |
Um estudo comparativo da micro e da macroestrutura de narrativas orais na lesão de hemisfério esquerdo e direito e sua relação com volumetria cerebral |
title_sort |
Um estudo comparativo da micro e da macroestrutura de narrativas orais na lesão de hemisfério esquerdo e direito e sua relação com volumetria cerebral |
author |
Schneider, Fernanda |
author_facet |
Schneider, Fernanda |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Hübner, Lilian Cristine |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/4814925793637987 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/0363765005528268 |
dc.contributor.author.fl_str_mv |
Schneider, Fernanda |
contributor_str_mv |
Hübner, Lilian Cristine |
dc.subject.por.fl_str_mv |
Produção Oral Microestrutura Macroestrutura Narrativa Memória de Trabalho Memória Semântica Acidente Vascular Cerebral VBM |
topic |
Produção Oral Microestrutura Macroestrutura Narrativa Memória de Trabalho Memória Semântica Acidente Vascular Cerebral VBM LINGUISTICA, LETRAS E ARTES::LETRAS |
dc.subject.cnpq.fl_str_mv |
LINGUISTICA, LETRAS E ARTES::LETRAS |
description |
This research aims to analyze the micro and macrostructure in the oral production of three narratives, produced from a sequence of pictures, comparing the performance of participants with right hemisphere damage (RHD) and participants with left hemisphere damage (LHD) with the performance of control groups. Furthermore, the linguistic analysis was related to data of memory constructs (working and semantic), reading and writing habits and brain volumetry. The research is divided into Study 1 and Study 2. For Study 1, 32 adult participants who suffered ischemic stroke were selected (with a minimum of four months before collection) to compose the experimental group – 16 participants in LHD and 16 participants in RHD aged between 50 to 79, with a minimum of two and maximum of 12 years of schooling; and 16 participants within the health control (CG), paired in age and schooling with the clinics. From these, 10 participants of each group – capable to perform magnetic resonance imaging exams – were selected to make part of Study 2, which relates data from neuropsychological and linguistic tasks to data from structural neuroimaging – known as Voxel-based morphometry (VBM). Inferential analysis in Study 1 showed that post-stroke writing and naming variables influenced significantly the performance in the micro and macrostructure, with the clinical group obtaining a statistically inferior result in the microstructure in relation to the CG. In relation to the macrostructure, there was also a significant correlation in the Digit span (working memory) in the three groups, but without statistical difference between the groups. In Study 2, LHD performance was significantly lower in the microstructure compared to RHD and CG. In the microstructure, in Study 2, the brain regions were grouped into four major components (CP). Thus, in the inferential analysis, all the main components of the brain areas (CP1, CP2, CP3 and CP4) showed a correlation with the microstructure variable, as well as significantly correlated post-stroke writing and naming variables. In the macrostructure, in Study 2, the variables that presented a statistically significant effect were GLH, writing habits after stroke, working memory and interaction between GLH variables and one of the main components of brain area (CP3). The parahippocampal area of the RH showed a correlation with CP3, which implies that this region significantly differentiates LHD from RHD in macrostructure processing. Thus, based on the analyzes and discussions proposed in the study, it was intended to contribute to the understanding of micro and macrostructure characterization in the production of oral narratives in right hemisphere and left hemisphere lesions and their correlation with cognitive constructs, more specifically of working memory and semantics and volume of brain areas involved. The work sought to advance in the discussion surrounding hemispheric specialization for the processing of oral discourse, especially of narratives, for the benefit of future research and clinical intervention. |
publishDate |
2018 |
dc.date.accessioned.fl_str_mv |
2018-12-17T12:08:18Z |
dc.date.issued.fl_str_mv |
2018-10-31 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://tede2.pucrs.br/tede2/handle/tede/8382 |
url |
http://tede2.pucrs.br/tede2/handle/tede/8382 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.program.fl_str_mv |
407477848473845987 |
dc.relation.confidence.fl_str_mv |
500 500 500 600 |
dc.relation.department.fl_str_mv |
-6557531471218110192 |
dc.relation.cnpq.fl_str_mv |
-5409419262886498088 |
dc.relation.sponsorship.fl_str_mv |
3590462550136975366 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Pontifícia Universidade Católica do Rio Grande do Sul |
dc.publisher.program.fl_str_mv |
Programa de Pós-Graduação em Letras |
dc.publisher.initials.fl_str_mv |
PUCRS |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Escola de Humanidades |
publisher.none.fl_str_mv |
Pontifícia Universidade Católica do Rio Grande do Sul |
dc.source.none.fl_str_mv |
reponame:Biblioteca Digital de Teses e Dissertações da PUC_RS instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) instacron:PUC_RS |
instname_str |
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
instacron_str |
PUC_RS |
institution |
PUC_RS |
reponame_str |
Biblioteca Digital de Teses e Dissertações da PUC_RS |
collection |
Biblioteca Digital de Teses e Dissertações da PUC_RS |
bitstream.url.fl_str_mv |
http://tede2.pucrs.br/tede2/bitstream/tede/8382/5/TES_FERNANDA_SCHNEIDER_COMPLETO.pdf http://tede2.pucrs.br/tede2/bitstream/tede/8382/4/TES_FERNANDA_SCHNEIDER_CONFIDENCIAL.pdf.jpg http://tede2.pucrs.br/tede2/bitstream/tede/8382/7/TES_FERNANDA_SCHNEIDER_COMPLETO.pdf.jpg http://tede2.pucrs.br/tede2/bitstream/tede/8382/3/TES_FERNANDA_SCHNEIDER_CONFIDENCIAL.pdf.txt http://tede2.pucrs.br/tede2/bitstream/tede/8382/6/TES_FERNANDA_SCHNEIDER_COMPLETO.pdf.txt http://tede2.pucrs.br/tede2/bitstream/tede/8382/1/license.txt |
bitstream.checksum.fl_str_mv |
10f51d3b651bfbe650679cd5e4cd2155 b4c07015d16169056164f4c090fefada cd47395a87797569ac2f31f448637698 8d9eb552b1f6df45c163831dd89baf40 e50aa2a60f09699d494e87719e8df5f2 220e11f2d3ba5354f917c7035aadef24 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Biblioteca Digital de Teses e Dissertações da PUC_RS - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
repository.mail.fl_str_mv |
biblioteca.central@pucrs.br|| |
_version_ |
1799765337039699968 |