Radiofrequência transvaginal no tratamento da incontinência urinária : ensaio clínico randomizado

Detalhes bibliográficos
Autor(a) principal: Almeida, Nadiessa Dorneles
Data de Publicação: 2020
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da PUC_RS
Texto Completo: http://tede2.pucrs.br/tede2/handle/tede/9297
Resumo: Urinary Incontinence (UI) is defined as any involuntary loss of urine. It is an extremely prevalent clinical condition, with negative interference in quality of life. Can be classified as stress urinary incontinence (SUI), urge urinary incontinence (UUI) and mixed urinary incontinence (MUI). Pelvic floor muscle strengthening exercises and behavioral changes are the first line of treatment for UI. Drug or surgical therapy may be performed for SUI, which are not exempt from side effects and associated risks. In view of this, the search for therapeutics with minimally invasive potential, such as transvaginal radiofrequency (RF), is increasing. The aim of this study was to evaluate the effectiveness of using transvaginal radiofrequency in the treatment of UI, to improve satisfaction with urinary symptoms. A randomized clinical trial was conducted with post-menopausal women, with SUI or MUI. The participants were divided into two groups: control group (CG) and intervention group (IG). All received guidance on pelvic floor muscle strengthening exercises and behavioral guidelines. All were instructed to perform the pelvic floor muscle strengthening exercises at home, daily. The CG received the transvaginal radiofrequency transducer off. The IG received the transducer turned on. The groups were evaluated through sociodemographic and clinical questions, UI-related quality of life questionnaire (ICIQ-SF), three-day voiding diary and physical examination of the pelvic floor, all before and after intervention. The treatment was performed once a month for three months. The reevaluation occurred after 30 days from the end of treatment. 36 patients were randomized, 27 concluded the therapy, 15 in the control group and 12 in the intervention group. The study population had a mean age of 58,9±5,4 years, about half were married and 63,9% of the sample didn’t lose urine in the physical exam. The sociodemographic profile of the groups was evaluated before treatment and showed no statistical difference between the groups. Both groups showed an improvement in the ICIQ-SF score and a reduction in the number of SUI episodes in the voiding diary, after treatment, showed no statistical difference between them. The nocturia parameter, when assessed in isolation, showed significantly superior improvement only in the radiofrequency group (3,4±1,8 to 2,0±2,3; p<0,02). Our study found that transvaginal radiofrequency did not demonstrate superiority over conservative treatment for SUI symptoms. However, there was an improvement in nocturia symptoms in the group that used RF, and it can be a promising treatment, especially for the reduction of this symptom. This finding can be related to local tissue remodeling, secundary to treatment.
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spelling Schneider, Rodolfo Herbertohttp://lattes.cnpq.br/3981128306152418http://lattes.cnpq.br/7629555640492046Almeida, Nadiessa Dorneles2020-10-29T17:02:30Z2020-03-27http://tede2.pucrs.br/tede2/handle/tede/9297Urinary Incontinence (UI) is defined as any involuntary loss of urine. It is an extremely prevalent clinical condition, with negative interference in quality of life. Can be classified as stress urinary incontinence (SUI), urge urinary incontinence (UUI) and mixed urinary incontinence (MUI). Pelvic floor muscle strengthening exercises and behavioral changes are the first line of treatment for UI. Drug or surgical therapy may be performed for SUI, which are not exempt from side effects and associated risks. In view of this, the search for therapeutics with minimally invasive potential, such as transvaginal radiofrequency (RF), is increasing. The aim of this study was to evaluate the effectiveness of using transvaginal radiofrequency in the treatment of UI, to improve satisfaction with urinary symptoms. A randomized clinical trial was conducted with post-menopausal women, with SUI or MUI. The participants were divided into two groups: control group (CG) and intervention group (IG). All received guidance on pelvic floor muscle strengthening exercises and behavioral guidelines. All were instructed to perform the pelvic floor muscle strengthening exercises at home, daily. The CG received the transvaginal radiofrequency transducer off. The IG received the transducer turned on. The groups were evaluated through sociodemographic and clinical questions, UI-related quality of life questionnaire (ICIQ-SF), three-day voiding diary and physical examination of the pelvic floor, all before and after intervention. The treatment was performed once a month for three months. The reevaluation occurred after 30 days from the end of treatment. 36 patients were randomized, 27 concluded the therapy, 15 in the control group and 12 in the intervention group. The study population had a mean age of 58,9±5,4 years, about half were married and 63,9% of the sample didn’t lose urine in the physical exam. The sociodemographic profile of the groups was evaluated before treatment and showed no statistical difference between the groups. Both groups showed an improvement in the ICIQ-SF score and a reduction in the number of SUI episodes in the voiding diary, after treatment, showed no statistical difference between them. The nocturia parameter, when assessed in isolation, showed significantly superior improvement only in the radiofrequency group (3,4±1,8 to 2,0±2,3; p<0,02). Our study found that transvaginal radiofrequency did not demonstrate superiority over conservative treatment for SUI symptoms. However, there was an improvement in nocturia symptoms in the group that used RF, and it can be a promising treatment, especially for the reduction of this symptom. This finding can be related to local tissue remodeling, secundary to treatment.A incontinência urinária (IU) é definida como qualquer perda involuntária de urina. É uma condição clínica extremamente prevalente, com interferência negativa na qualidade de vida. Pode ser classificada como incontinência urinária de esforço (IUE), incontinência urinária de urgência (IUU) e incontinência urinária mista (IUM). Os exercícios de reforço da musculatura pélvica e modificações comportamentais são a primeira linha de tratamento para a IU. Pode-se realizar terapia medicamentosa ou cirúrgica para a IUE, que não são isentas de efeitos colaterais e riscos associados. Em vista disto, aumenta-se a busca por terapêuticas com potencial minimamente invasivo, como a radiofrequência transvaginal. O objetivo deste estudo, foi avaliar a eficácia do uso de radiofrequência transvaginal no tratamento da IU, para melhora da satisfação em relação aos sintomas urinários. Foi realizado um ensaio clínico randomizado, com mulheres pós menopáusicas, que apresentavam IUE ou IUM. As participantes foram divididas em dois grupos: grupo controle (GC) e grupo intervenção (GI). Todas receberam orientações quanto aos exercícios de reforço da musculatura pélvica e orientações comportamentais. Todas as mulheres foram orientadas a realizar o exercício de reforço da musculatura pélvica domiciliar, diariamente. O GC recebeu o transdutor de radiofrequência transvaginal desligado. O GI recebeu o transdutor ligado. Os grupos foram avaliados através de perguntas sociodemográficas e clínicas, questionário de qualidade de vida relacionado à IU (ICIQ-SF), diário miccional de três dias e exame físico do assoalho pélvico vaginal, todos pré e pós intervenção. O tratamento foi realizado uma vez por mês, durante três meses. A reavaliação ocorreu após 30 dias do término do tratamento. Foram randomizadas 36 pacientes, 27 delas concluíram a terapia, 15 no grupo controle e 12 no grupo intervenção. A população em estudo apresentou média de idade de 58,9±5,4 anos, cerca de metade era casada e 63,9% da amostra não perdeu urina no exame físico. O perfil socio demográfico dos grupos foi avaliado antes do tratamento, não havendo diferença estatística entre os grupos. Ambos os grupos apresentaram melhora no escore do ICIQ-SF e redução no número de episódios de IUE no diário miccional, após o tratamento, não havendo diferença estatística entre eles. O parâmetro noctúria, quando avaliado isoladamente, apresentou melhora estatisticamente significativa apenas no GI (3,4±1,8 para 2,0±2,3, p< 0,02). Nosso estudo constatou que a radiofrequência transvaginal não demonstrou superioridade em relação ao tratamento conservador para os sintomas de IUE. Entretanto, observou-se uma melhora dos sintomas de noctúria no grupo que realizou a RF, podendo ser um tratamento promissor, principalmente para a redução deste sintoma. Este achado pode estar relacionado a remodelação tecidual local, secundária ao tratamento.Submitted by PPG Gerontologia Biomédica (geronbio@pucrs.br) on 2020-07-22T18:46:58Z No. of bitstreams: 1 ALMEIDA_NADIESSA_DORNELES_DIS.pdf: 2637213 bytes, checksum: 992ce52113c5d2ff1f1c78eb918cc976 (MD5)Approved for entry into archive by Sarajane Pan (sarajane.pan@pucrs.br) on 2020-10-29T16:47:29Z (GMT) No. of bitstreams: 1 ALMEIDA_NADIESSA_DORNELES_DIS.pdf: 2637213 bytes, checksum: 992ce52113c5d2ff1f1c78eb918cc976 (MD5)Made available in DSpace on 2020-10-29T17:02:30Z (GMT). No. of bitstreams: 1 ALMEIDA_NADIESSA_DORNELES_DIS.pdf: 2637213 bytes, checksum: 992ce52113c5d2ff1f1c78eb918cc976 (MD5) Previous issue date: 2020-03-27Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESapplication/pdfhttp://tede2.pucrs.br:80/tede2/retrieve/179211/ALMEIDA_NADIESSA_DORNELES_DIS.pdf.jpgporPontifícia Universidade Católica do Rio Grande do SulPrograma de Pós-Graduação em Gerontologia BiomédicaPUCRSBrasilEscola de MedicinaIncontinência urináriaRadiofrequênciaSíndrome geniturinária da menopausaEnvelhecimentoCIENCIAS DA SAUDE::MEDICINARadiofrequência transvaginal no tratamento da incontinência urinária : ensaio clínico randomizadoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisTrabalho não apresenta restrição para publicação8969645070886364160500600500600-224747486637135387-9693694523087866273590462550136975366info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da PUC_RSinstname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSTHUMBNAILALMEIDA_NADIESSA_DORNELES_DIS.pdf.jpgALMEIDA_NADIESSA_DORNELES_DIS.pdf.jpgimage/jpeg5598http://tede2.pucrs.br/tede2/bitstream/tede/9297/4/ALMEIDA_NADIESSA_DORNELES_DIS.pdf.jpg6837bdf849add15c573b0c3c72a94303MD54TEXTALMEIDA_NADIESSA_DORNELES_DIS.pdf.txtALMEIDA_NADIESSA_DORNELES_DIS.pdf.txttext/plain130985http://tede2.pucrs.br/tede2/bitstream/tede/9297/3/ALMEIDA_NADIESSA_DORNELES_DIS.pdf.txta84ace34671bfe2f5eebbdf80da259eaMD53ORIGINALALMEIDA_NADIESSA_DORNELES_DIS.pdfALMEIDA_NADIESSA_DORNELES_DIS.pdfapplication/pdf2637213http://tede2.pucrs.br/tede2/bitstream/tede/9297/2/ALMEIDA_NADIESSA_DORNELES_DIS.pdf992ce52113c5d2ff1f1c78eb918cc976MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-8590http://tede2.pucrs.br/tede2/bitstream/tede/9297/1/license.txt220e11f2d3ba5354f917c7035aadef24MD51tede/92972020-10-29 21:00:12.064oai:tede2.pucrs.br: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Biblioteca Digital de Teses e Dissertaçõeshttp://tede2.pucrs.br/tede2/PRIhttps://tede2.pucrs.br/oai/requestbiblioteca.central@pucrs.br||opendoar:2020-10-29T23:00:12Biblioteca Digital de Teses e Dissertações da PUC_RS - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.por.fl_str_mv Radiofrequência transvaginal no tratamento da incontinência urinária : ensaio clínico randomizado
title Radiofrequência transvaginal no tratamento da incontinência urinária : ensaio clínico randomizado
spellingShingle Radiofrequência transvaginal no tratamento da incontinência urinária : ensaio clínico randomizado
Almeida, Nadiessa Dorneles
Incontinência urinária
Radiofrequência
Síndrome geniturinária da menopausa
Envelhecimento
CIENCIAS DA SAUDE::MEDICINA
title_short Radiofrequência transvaginal no tratamento da incontinência urinária : ensaio clínico randomizado
title_full Radiofrequência transvaginal no tratamento da incontinência urinária : ensaio clínico randomizado
title_fullStr Radiofrequência transvaginal no tratamento da incontinência urinária : ensaio clínico randomizado
title_full_unstemmed Radiofrequência transvaginal no tratamento da incontinência urinária : ensaio clínico randomizado
title_sort Radiofrequência transvaginal no tratamento da incontinência urinária : ensaio clínico randomizado
author Almeida, Nadiessa Dorneles
author_facet Almeida, Nadiessa Dorneles
author_role author
dc.contributor.advisor1.fl_str_mv Schneider, Rodolfo Herberto
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/3981128306152418
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/7629555640492046
dc.contributor.author.fl_str_mv Almeida, Nadiessa Dorneles
contributor_str_mv Schneider, Rodolfo Herberto
dc.subject.por.fl_str_mv Incontinência urinária
Radiofrequência
Síndrome geniturinária da menopausa
Envelhecimento
topic Incontinência urinária
Radiofrequência
Síndrome geniturinária da menopausa
Envelhecimento
CIENCIAS DA SAUDE::MEDICINA
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE::MEDICINA
description Urinary Incontinence (UI) is defined as any involuntary loss of urine. It is an extremely prevalent clinical condition, with negative interference in quality of life. Can be classified as stress urinary incontinence (SUI), urge urinary incontinence (UUI) and mixed urinary incontinence (MUI). Pelvic floor muscle strengthening exercises and behavioral changes are the first line of treatment for UI. Drug or surgical therapy may be performed for SUI, which are not exempt from side effects and associated risks. In view of this, the search for therapeutics with minimally invasive potential, such as transvaginal radiofrequency (RF), is increasing. The aim of this study was to evaluate the effectiveness of using transvaginal radiofrequency in the treatment of UI, to improve satisfaction with urinary symptoms. A randomized clinical trial was conducted with post-menopausal women, with SUI or MUI. The participants were divided into two groups: control group (CG) and intervention group (IG). All received guidance on pelvic floor muscle strengthening exercises and behavioral guidelines. All were instructed to perform the pelvic floor muscle strengthening exercises at home, daily. The CG received the transvaginal radiofrequency transducer off. The IG received the transducer turned on. The groups were evaluated through sociodemographic and clinical questions, UI-related quality of life questionnaire (ICIQ-SF), three-day voiding diary and physical examination of the pelvic floor, all before and after intervention. The treatment was performed once a month for three months. The reevaluation occurred after 30 days from the end of treatment. 36 patients were randomized, 27 concluded the therapy, 15 in the control group and 12 in the intervention group. The study population had a mean age of 58,9±5,4 years, about half were married and 63,9% of the sample didn’t lose urine in the physical exam. The sociodemographic profile of the groups was evaluated before treatment and showed no statistical difference between the groups. Both groups showed an improvement in the ICIQ-SF score and a reduction in the number of SUI episodes in the voiding diary, after treatment, showed no statistical difference between them. The nocturia parameter, when assessed in isolation, showed significantly superior improvement only in the radiofrequency group (3,4±1,8 to 2,0±2,3; p<0,02). Our study found that transvaginal radiofrequency did not demonstrate superiority over conservative treatment for SUI symptoms. However, there was an improvement in nocturia symptoms in the group that used RF, and it can be a promising treatment, especially for the reduction of this symptom. This finding can be related to local tissue remodeling, secundary to treatment.
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