Occupational Allergic Contact Dermatitis Caused by Epoxy Resin in the Centre of Portugal
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.29021/spdv.77.3.1109 |
Resumo: | Introduction. Occupational Allergic Contact Dermatitis is a very common occupational disease and epoxy resins are among its main causes. The aim of this study was to characterize patients with positive patch test reactions to epoxy resin detected in the Coimbra Hospital and University Center between 2012 and 2018 and compare with the results of patients patch tested between 1999 and 2008 at the same Institution. Method and Materials. Within aretrospective analysis of the files of patients with positive patch test reactions (1+ or more intense) to epoxy resin of bisfenol A tested at 1% pet. within the Baseline Series between 2012 and 2018, we characterized demographic and clinical data of reactive patients, evaluated the relevance of the reaction, sources of exposure to epoxy resin with particular attention to occupational exposures, other positive reactions and the impact of the results of the tests in the work conditions of these patients. Lastly, we compared these results with a previous study performed in the same Hospital between 1999 and 2008. Results. Among 2363 patch tested patients during the study period we found 23 patients (0.97%), 17 males and 6 females, who developed contact allergy to epoxy resins. In 22 cases we identified a relevant occupational exposure: 9 from construction industry; 9 workers from wind-mill turbines factory for Eolic energy; 2 from fiberglass factories; 1 from a chemical factory and 1 from a Wastewater Treatment Plant. In 1 patient (a teacher) no relevance was found. Of these 22 workers, 9 (39.1%) had both hand and airborne lesions, while 8 (34.8%) had lesions exclusively on the hands and 5 (21.7%) had predominately airborne dermatitis. Four of the 23 (17.4%) reacted exclusively to the epoxy resin, and 11 of 18 (61.1%) also reacted to 0.25% hexanediol diglycidyl ether. Avoidance resulted in a significant improvement of symptoms. Compared to the previous period (1999-2008), there are no significative changes apart from a slight increase in the frequency of the allergic reactions to epoxy resins and its main source of exposure. Conclusions. The prevalence of allergic contact dermatitis to epoxy resin has slightly increased in this Portuguese Center mostly due to workers from wind-mill turbines factory for Eolic energy, a recent industry implanted in this region. This allergen still causes almost exclusively occupational dermatitis, either hand, airborne, or both. |
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Occupational Allergic Contact Dermatitis Caused by Epoxy Resin in the Centre of PortugalDermatite de Contacto Ocupacional por Resina Epóxi no Centro de PortugalDermatitis, Allergic ContactEpoxy CompoundsEpoxy ResinsOccupational ExposureCompostos de EpóxiDermatite Alérgica de ContatoDermatite OcupacionalExposição OcupacionalResinas EpóxiIntroduction. Occupational Allergic Contact Dermatitis is a very common occupational disease and epoxy resins are among its main causes. The aim of this study was to characterize patients with positive patch test reactions to epoxy resin detected in the Coimbra Hospital and University Center between 2012 and 2018 and compare with the results of patients patch tested between 1999 and 2008 at the same Institution. Method and Materials. Within aretrospective analysis of the files of patients with positive patch test reactions (1+ or more intense) to epoxy resin of bisfenol A tested at 1% pet. within the Baseline Series between 2012 and 2018, we characterized demographic and clinical data of reactive patients, evaluated the relevance of the reaction, sources of exposure to epoxy resin with particular attention to occupational exposures, other positive reactions and the impact of the results of the tests in the work conditions of these patients. Lastly, we compared these results with a previous study performed in the same Hospital between 1999 and 2008. Results. Among 2363 patch tested patients during the study period we found 23 patients (0.97%), 17 males and 6 females, who developed contact allergy to epoxy resins. In 22 cases we identified a relevant occupational exposure: 9 from construction industry; 9 workers from wind-mill turbines factory for Eolic energy; 2 from fiberglass factories; 1 from a chemical factory and 1 from a Wastewater Treatment Plant. In 1 patient (a teacher) no relevance was found. Of these 22 workers, 9 (39.1%) had both hand and airborne lesions, while 8 (34.8%) had lesions exclusively on the hands and 5 (21.7%) had predominately airborne dermatitis. Four of the 23 (17.4%) reacted exclusively to the epoxy resin, and 11 of 18 (61.1%) also reacted to 0.25% hexanediol diglycidyl ether. Avoidance resulted in a significant improvement of symptoms. Compared to the previous period (1999-2008), there are no significative changes apart from a slight increase in the frequency of the allergic reactions to epoxy resins and its main source of exposure. Conclusions. The prevalence of allergic contact dermatitis to epoxy resin has slightly increased in this Portuguese Center mostly due to workers from wind-mill turbines factory for Eolic energy, a recent industry implanted in this region. This allergen still causes almost exclusively occupational dermatitis, either hand, airborne, or both.Introdução. A Dermatite de Contato Alérgica Ocupacional é uma doença ocupacional muito comum e os produtos químicos epóxi estão entre as suas principais causas. O objetivo deste estudo foi caraterizar os doentes com reações positivas à resina epóxi nos testes epicutâneos realizados no Centro Hospitalar e Universitário de Coimbra entre 2012 e 2018, e comparar com os resultados obtidos entre 1999 e 2008 na mesma instituição. Método e Materiais.Realizámos uma análise retrospetiva dos resultados dos testes epicutâneos realizados entre 2012 e 2018 e identificámos os doentes com reações positivas à resina epóxi de bisfenol A testada a 1% em vaselina na Série Básica. Caraterizámos os seus dados demográficos e clínicos, avaliámos a relevância do resultado, as fontes de exposição à resina epóxi com particular atenção às fontes ocupacionais, outras reações positivas, e o impacto dos resultados dos testes no âmbito ocupacional destes trabalhadores. Por último, comparámos estes resultados com os de um estudo anterior realizado no mesmo hospital entre 1999 e 2008. Resultados. Dos 2363 doentes submetidos a testes epicutâneos no período de 2012-2018, foram encontrados 23 doentes (0.97%) que desenvolveram alergia de contacto à resina epóxi. Em 22 casos identificámos uma exposição ocupacional relevante: 9 na indústria da construção civil, 9 trabalhadores em fábrica de turbinas para energia eólica, 2 em fábricas de fibra de vidro, 1 numa fábrica de produtos químicos e 1 numa estação de tratamento de águas residuais. Um dos 23 doentes era professor e não tinha exposição ocupacional relevante. Destes 22 trabalhadores, 9 (39.1%) apresentavam lesões tanto nas mãos como do tipo airborne,enquanto que 8 (34.8%) apresentavam lesões exclusivamente nas mãos e 5 (21.7%) apenas do tipo airborne. Quatro dos 23 (17.4%) reagiram exclusivamente à resina epóxi, e 11 dos 18 testados (61.1%) reagiram também ao hexanodioldiglicidil éter a 0.25% em vaselina. A evicção da exposição resultou numa melhoria significativa dos sintomas. Em comparação com o período analisado previamente (1999-2008), não houve mudanças epidemiológicas significativas, além de um discreto aumento na frequência das reações à resina epóxi e da sua principal fonte de exposição. Conclusões.A prevalência da dermatite de contacto alérgica à resina epóxi aumentou ligeiramente neste Centro Português, o que poderá estar relacionado com o surgimento de uma nova fábrica de turbinas para produção de energia Eólica nesta região. Este alergénio continua a causar quase exclusivamente dermatites ocupacionais, tanto nas mãos, do tipo airborne, ou ambas.Sociedade Portuguesa de Dermatologia e Venereologia2019-10-10T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.77.3.1109oai:ojs.revista.spdv.com.pt:article/1109Journal of the Portuguese Society of Dermatology and Venereology; Vol 77 No 3 (2019): July / September; 221-225Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 77 n. 3 (2019): Julho / Setembro; 221-2252182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://revista.spdv.com.pt/index.php/spdv/article/view/1109https://doi.org/10.29021/spdv.77.3.1109https://revista.spdv.com.pt/index.php/spdv/article/view/1109/788Ferreira Bastos, MarianaBatista , RicardoLaertes , DiogoCalvão , JoanaGonçalo , Margaridainfo:eu-repo/semantics/openAccess2022-10-06T12:35:12Zoai:ojs.revista.spdv.com.pt:article/1109Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:10.983555Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Occupational Allergic Contact Dermatitis Caused by Epoxy Resin in the Centre of Portugal Dermatite de Contacto Ocupacional por Resina Epóxi no Centro de Portugal |
title |
Occupational Allergic Contact Dermatitis Caused by Epoxy Resin in the Centre of Portugal |
spellingShingle |
Occupational Allergic Contact Dermatitis Caused by Epoxy Resin in the Centre of Portugal Ferreira Bastos, Mariana Dermatitis, Allergic Contact Epoxy Compounds Epoxy Resins Occupational Exposure Compostos de Epóxi Dermatite Alérgica de Contato Dermatite Ocupacional Exposição Ocupacional Resinas Epóxi |
title_short |
Occupational Allergic Contact Dermatitis Caused by Epoxy Resin in the Centre of Portugal |
title_full |
Occupational Allergic Contact Dermatitis Caused by Epoxy Resin in the Centre of Portugal |
title_fullStr |
Occupational Allergic Contact Dermatitis Caused by Epoxy Resin in the Centre of Portugal |
title_full_unstemmed |
Occupational Allergic Contact Dermatitis Caused by Epoxy Resin in the Centre of Portugal |
title_sort |
Occupational Allergic Contact Dermatitis Caused by Epoxy Resin in the Centre of Portugal |
author |
Ferreira Bastos, Mariana |
author_facet |
Ferreira Bastos, Mariana Batista , Ricardo Laertes , Diogo Calvão , Joana Gonçalo , Margarida |
author_role |
author |
author2 |
Batista , Ricardo Laertes , Diogo Calvão , Joana Gonçalo , Margarida |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Ferreira Bastos, Mariana Batista , Ricardo Laertes , Diogo Calvão , Joana Gonçalo , Margarida |
dc.subject.por.fl_str_mv |
Dermatitis, Allergic Contact Epoxy Compounds Epoxy Resins Occupational Exposure Compostos de Epóxi Dermatite Alérgica de Contato Dermatite Ocupacional Exposição Ocupacional Resinas Epóxi |
topic |
Dermatitis, Allergic Contact Epoxy Compounds Epoxy Resins Occupational Exposure Compostos de Epóxi Dermatite Alérgica de Contato Dermatite Ocupacional Exposição Ocupacional Resinas Epóxi |
description |
Introduction. Occupational Allergic Contact Dermatitis is a very common occupational disease and epoxy resins are among its main causes. The aim of this study was to characterize patients with positive patch test reactions to epoxy resin detected in the Coimbra Hospital and University Center between 2012 and 2018 and compare with the results of patients patch tested between 1999 and 2008 at the same Institution. Method and Materials. Within aretrospective analysis of the files of patients with positive patch test reactions (1+ or more intense) to epoxy resin of bisfenol A tested at 1% pet. within the Baseline Series between 2012 and 2018, we characterized demographic and clinical data of reactive patients, evaluated the relevance of the reaction, sources of exposure to epoxy resin with particular attention to occupational exposures, other positive reactions and the impact of the results of the tests in the work conditions of these patients. Lastly, we compared these results with a previous study performed in the same Hospital between 1999 and 2008. Results. Among 2363 patch tested patients during the study period we found 23 patients (0.97%), 17 males and 6 females, who developed contact allergy to epoxy resins. In 22 cases we identified a relevant occupational exposure: 9 from construction industry; 9 workers from wind-mill turbines factory for Eolic energy; 2 from fiberglass factories; 1 from a chemical factory and 1 from a Wastewater Treatment Plant. In 1 patient (a teacher) no relevance was found. Of these 22 workers, 9 (39.1%) had both hand and airborne lesions, while 8 (34.8%) had lesions exclusively on the hands and 5 (21.7%) had predominately airborne dermatitis. Four of the 23 (17.4%) reacted exclusively to the epoxy resin, and 11 of 18 (61.1%) also reacted to 0.25% hexanediol diglycidyl ether. Avoidance resulted in a significant improvement of symptoms. Compared to the previous period (1999-2008), there are no significative changes apart from a slight increase in the frequency of the allergic reactions to epoxy resins and its main source of exposure. Conclusions. The prevalence of allergic contact dermatitis to epoxy resin has slightly increased in this Portuguese Center mostly due to workers from wind-mill turbines factory for Eolic energy, a recent industry implanted in this region. This allergen still causes almost exclusively occupational dermatitis, either hand, airborne, or both. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-10T00:00:00Z |
dc.type.driver.fl_str_mv |
journal article info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.29021/spdv.77.3.1109 oai:ojs.revista.spdv.com.pt:article/1109 |
url |
https://doi.org/10.29021/spdv.77.3.1109 |
identifier_str_mv |
oai:ojs.revista.spdv.com.pt:article/1109 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://revista.spdv.com.pt/index.php/spdv/article/view/1109 https://doi.org/10.29021/spdv.77.3.1109 https://revista.spdv.com.pt/index.php/spdv/article/view/1109/788 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
dc.source.none.fl_str_mv |
Journal of the Portuguese Society of Dermatology and Venereology; Vol 77 No 3 (2019): July / September; 221-225 Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 77 n. 3 (2019): Julho / Setembro; 221-225 2182-2409 2182-2395 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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