OCCUPATIONAL ALLERGIC CONTACT DERMATITIS TO MERCAPTOBENZOTIAZOL

Detalhes bibliográficos
Autor(a) principal: Araújo, Catarina
Data de Publicação: 2015
Outros Autores: Resende, C., Pereira, T., Fernandes, José Carlos, Brito, Celeste
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.29021/spdv.72.4.324
Resumo: Introduction: Allergic contact dermatitis to mercaptobenzothiazole and its derivatives has been increasingly recognized in industrialized countries because of their widespread use in polymerization of synthetic rubber. The authors describe two clinical cases with relevant occupational exposure.Case reports: A 46 year-old male patient, with an eight month pruritic dermatitis, limited to the wrists, refractory to high potency topical corticosteroid and oral antihistamine. Physical examination showed erythematous-violaceous infiltrated plaques and excoriated erythematous papules on both wrists. Prick tests and RAST to latex were negative. Epicutaneous tests were performed with basic series from Portuguese Contact Dermatitis Group, rubber and glue series and fragments of the sleeve and it was found positivity for mercaptobenzothiazole (++), mercapto mix (++) and elastic band of gloves in reading at 72h and at 7 days. A 61 years old non atopic man, woodworker, with a 12- month history of itching, erythema, infiltration of genius region of face and extension to posterior cervical region.Epicutaneous tests were performed with basic series from Portuguese Contact Dermatitis Group, rubber and glue series, cosmetics series and fragments of the protection mask work and it was found positivity for mercaptobenzothiazole (++), mercapto mix (++) and elastic band of mask (++) in reading at 72h and at 7 days.Discussion: Despite being well known allergens, mercaptobenzothiazole and its derivatives may be present in other sources of exposure to rubber like elastic fabric in clothing. Once the worker sensitized, it can be an important cause of disability in an occupational and personnal setting.
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spelling OCCUPATIONAL ALLERGIC CONTACT DERMATITIS TO MERCAPTOBENZOTIAZOLDERMATITE DE CONTACTO ALÉRGICA PROFISSIONAL AO MERCAPTOBENZOTIAZOLBenzothiazolesDermatitisAllergic contactoccupationalBenzotiazóisDermatite de contacto alérgicaDermatite ocupacionalIntroduction: Allergic contact dermatitis to mercaptobenzothiazole and its derivatives has been increasingly recognized in industrialized countries because of their widespread use in polymerization of synthetic rubber. The authors describe two clinical cases with relevant occupational exposure.Case reports: A 46 year-old male patient, with an eight month pruritic dermatitis, limited to the wrists, refractory to high potency topical corticosteroid and oral antihistamine. Physical examination showed erythematous-violaceous infiltrated plaques and excoriated erythematous papules on both wrists. Prick tests and RAST to latex were negative. Epicutaneous tests were performed with basic series from Portuguese Contact Dermatitis Group, rubber and glue series and fragments of the sleeve and it was found positivity for mercaptobenzothiazole (++), mercapto mix (++) and elastic band of gloves in reading at 72h and at 7 days. A 61 years old non atopic man, woodworker, with a 12- month history of itching, erythema, infiltration of genius region of face and extension to posterior cervical region.Epicutaneous tests were performed with basic series from Portuguese Contact Dermatitis Group, rubber and glue series, cosmetics series and fragments of the protection mask work and it was found positivity for mercaptobenzothiazole (++), mercapto mix (++) and elastic band of mask (++) in reading at 72h and at 7 days.Discussion: Despite being well known allergens, mercaptobenzothiazole and its derivatives may be present in other sources of exposure to rubber like elastic fabric in clothing. Once the worker sensitized, it can be an important cause of disability in an occupational and personnal setting.Introdução: A dermatite de contacto alérgica ao mercaptobenzotiazol e seus derivados tem sido reconhecida de forma crescente nos países industrializados devido ao seu uso alargado na polimerização da borracha sintética. Os autores descrevem dois casos clínicos com relevante exposição profissional.Caso 1: Homem de 46 anos, trabalhador na construção civil, com uma dermatite de oito meses de evolução, pruriginosa, localizada apenas nos punhos, refratária a corticóide tópico de alta potência e anti-histamínico oral. Ao exame objetivo apresentava placas eritemato-violáceas infiltradas e pápulas eritematosas escoriadas em ambos os punhos. Os testes Prick e RAST ao latex foram negativos. Foram efetuados testes epicutâneos com a bateria padrão do Grupo Português de Estudo de Dermatite de Contacto, bateria de borrachas, bateria de colas e fragmentos da própria luva tendo-se verificado positividade ao mercaptobenzotiazol (++), mistura de mercapto (++) e à faixa elástica presente no punho das luvas, às 72h e aos 7 dias.Caso 2: Homem de 61 anos, carpinteiro, com placas eritematosas infiltradas, pruriginosas, na região geniana e extensão para região cervical posterior, com cerca de 12 meses de evolução. Foram realizados testes epicutâneos com a bateria padrão do Grupo Português de Estudo de Dermatite de Contacto, bateria de borrachas e colas, bateria de cosméticos e fragmentos da própria máscara de proteção. Verificou-se positividade para mercaptobenzotiazol (+ +), mistura mercapto (+ +) e elástico de máscara (+ +) na leitura das 72 horas e aos 7 dias.Discussão: Apesar de serem alergénios bem conhecidos, o mercaptobenzotiazol e seus derivados podem estar presentes noutras fontes de exposição à borracha como o tecido elástico no vestuário. Uma vez o trabalhador sensibilizado, pode ser causa de incapacidade quer para a profissão quer para as atividades de vida diária.Sociedade Portuguesa de Dermatologia e Venereologia2015-04-13T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.72.4.324oai:ojs.revista.spdv.com.pt:article/324Journal of the Portuguese Society of Dermatology and Venereology; Vol 72 No 4 (2014): Outubro - Dezembro; 541-545Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 72 n. 4 (2014): Outubro - Dezembro; 541-5452182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/324https://doi.org/10.29021/spdv.72.4.324https://revista.spdv.com.pt/index.php/spdv/article/view/324/298Araújo, CatarinaResende, C.Pereira, T.Fernandes, José CarlosBrito, Celesteinfo:eu-repo/semantics/openAccess2022-10-06T12:34:50Zoai:ojs.revista.spdv.com.pt:article/324Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:10:50.453234Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv OCCUPATIONAL ALLERGIC CONTACT DERMATITIS TO MERCAPTOBENZOTIAZOL
DERMATITE DE CONTACTO ALÉRGICA PROFISSIONAL AO MERCAPTOBENZOTIAZOL
title OCCUPATIONAL ALLERGIC CONTACT DERMATITIS TO MERCAPTOBENZOTIAZOL
spellingShingle OCCUPATIONAL ALLERGIC CONTACT DERMATITIS TO MERCAPTOBENZOTIAZOL
Araújo, Catarina
Benzothiazoles
Dermatitis
Allergic contact
occupational
Benzotiazóis
Dermatite de contacto alérgica
Dermatite ocupacional
title_short OCCUPATIONAL ALLERGIC CONTACT DERMATITIS TO MERCAPTOBENZOTIAZOL
title_full OCCUPATIONAL ALLERGIC CONTACT DERMATITIS TO MERCAPTOBENZOTIAZOL
title_fullStr OCCUPATIONAL ALLERGIC CONTACT DERMATITIS TO MERCAPTOBENZOTIAZOL
title_full_unstemmed OCCUPATIONAL ALLERGIC CONTACT DERMATITIS TO MERCAPTOBENZOTIAZOL
title_sort OCCUPATIONAL ALLERGIC CONTACT DERMATITIS TO MERCAPTOBENZOTIAZOL
author Araújo, Catarina
author_facet Araújo, Catarina
Resende, C.
Pereira, T.
Fernandes, José Carlos
Brito, Celeste
author_role author
author2 Resende, C.
Pereira, T.
Fernandes, José Carlos
Brito, Celeste
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Araújo, Catarina
Resende, C.
Pereira, T.
Fernandes, José Carlos
Brito, Celeste
dc.subject.por.fl_str_mv Benzothiazoles
Dermatitis
Allergic contact
occupational
Benzotiazóis
Dermatite de contacto alérgica
Dermatite ocupacional
topic Benzothiazoles
Dermatitis
Allergic contact
occupational
Benzotiazóis
Dermatite de contacto alérgica
Dermatite ocupacional
description Introduction: Allergic contact dermatitis to mercaptobenzothiazole and its derivatives has been increasingly recognized in industrialized countries because of their widespread use in polymerization of synthetic rubber. The authors describe two clinical cases with relevant occupational exposure.Case reports: A 46 year-old male patient, with an eight month pruritic dermatitis, limited to the wrists, refractory to high potency topical corticosteroid and oral antihistamine. Physical examination showed erythematous-violaceous infiltrated plaques and excoriated erythematous papules on both wrists. Prick tests and RAST to latex were negative. Epicutaneous tests were performed with basic series from Portuguese Contact Dermatitis Group, rubber and glue series and fragments of the sleeve and it was found positivity for mercaptobenzothiazole (++), mercapto mix (++) and elastic band of gloves in reading at 72h and at 7 days. A 61 years old non atopic man, woodworker, with a 12- month history of itching, erythema, infiltration of genius region of face and extension to posterior cervical region.Epicutaneous tests were performed with basic series from Portuguese Contact Dermatitis Group, rubber and glue series, cosmetics series and fragments of the protection mask work and it was found positivity for mercaptobenzothiazole (++), mercapto mix (++) and elastic band of mask (++) in reading at 72h and at 7 days.Discussion: Despite being well known allergens, mercaptobenzothiazole and its derivatives may be present in other sources of exposure to rubber like elastic fabric in clothing. Once the worker sensitized, it can be an important cause of disability in an occupational and personnal setting.
publishDate 2015
dc.date.none.fl_str_mv 2015-04-13T00:00:00Z
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dc.identifier.uri.fl_str_mv https://doi.org/10.29021/spdv.72.4.324
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dc.relation.none.fl_str_mv https://revista.spdv.com.pt/index.php/spdv/article/view/324
https://doi.org/10.29021/spdv.72.4.324
https://revista.spdv.com.pt/index.php/spdv/article/view/324/298
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 72 No 4 (2014): Outubro - Dezembro; 541-545
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 72 n. 4 (2014): Outubro - Dezembro; 541-545
2182-2409
2182-2395
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