Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.22/22262 |
Resumo: | The pancreas is a highly important organ, since it produces insulin and prevents the occurrence of diabetes. Although rare, pancreatic cancer is highly lethal, with a small life expectancy after being diagnosed. The pancreas is one of the organs less studied in the field of biophotonics. With the objective of acquiring information that can be used in the development of future applications to diagnose and treat pancreas diseases, the spectral optical properties of the rabbit pancreas were evaluated in a broad-spectral range, between 200 and 1000 nm. The method used to obtain such optical properties is simple, based almost on direct calculations from spectral measurements. The optical properties obtained show similar wavelength dependencies to the ones obtained for other tissues, but a further analysis on the spectral absorption coefficient showed that the pancreas tissues contain pigments, namely melanin, and lipofuscin. Using a simple calculation, it was possible to retrieve similar contents of these pigments from the absorption spectrum of the pancreas, which indicates that they accumulate in the same proportion as a result of the aging process. Such pigment accumulation was camouflaging the real contents of DNA, hemoglobin, and water, which were precisely evaluated after subtracting the pigment absorption. |
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Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content AnalysisPancreas tissueOptical propertiesScattering coefficientAbsorption coefficientPigment detectionThe pancreas is a highly important organ, since it produces insulin and prevents the occurrence of diabetes. Although rare, pancreatic cancer is highly lethal, with a small life expectancy after being diagnosed. The pancreas is one of the organs less studied in the field of biophotonics. With the objective of acquiring information that can be used in the development of future applications to diagnose and treat pancreas diseases, the spectral optical properties of the rabbit pancreas were evaluated in a broad-spectral range, between 200 and 1000 nm. The method used to obtain such optical properties is simple, based almost on direct calculations from spectral measurements. The optical properties obtained show similar wavelength dependencies to the ones obtained for other tissues, but a further analysis on the spectral absorption coefficient showed that the pancreas tissues contain pigments, namely melanin, and lipofuscin. Using a simple calculation, it was possible to retrieve similar contents of these pigments from the absorption spectrum of the pancreas, which indicates that they accumulate in the same proportion as a result of the aging process. Such pigment accumulation was camouflaging the real contents of DNA, hemoglobin, and water, which were precisely evaluated after subtracting the pigment absorption.The work of I.S.M. was supported by the Portuguese Science Foundation, grant no. FCTUIDB/ 151528/2021. The work of H.F.S and L.M.O. was supported by the Portuguese Science Foundation, grant No. FCT-UIDB/04730/2020. The work of V.V.T. was supported by a grant under the Decree of the Government of the Russian Federation No. 220 of 09 April 2010 (Agreement No. 075-15-2021-615 of 4 June 2021).MDPIRepositório Científico do Instituto Politécnico do PortoMartins, Inês SoraiaSilva, Hugo FilipeTuchin, Valery VictorovichOliveira, Luís Manuel2023-02-14T09:29:12Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/22262eng10.3390/photonics9020122info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T13:18:52Zoai:recipp.ipp.pt:10400.22/22262Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:42:19.391632Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis |
title |
Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis |
spellingShingle |
Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis Martins, Inês Soraia Pancreas tissue Optical properties Scattering coefficient Absorption coefficient Pigment detection |
title_short |
Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis |
title_full |
Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis |
title_fullStr |
Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis |
title_full_unstemmed |
Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis |
title_sort |
Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis |
author |
Martins, Inês Soraia |
author_facet |
Martins, Inês Soraia Silva, Hugo Filipe Tuchin, Valery Victorovich Oliveira, Luís Manuel |
author_role |
author |
author2 |
Silva, Hugo Filipe Tuchin, Valery Victorovich Oliveira, Luís Manuel |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Politécnico do Porto |
dc.contributor.author.fl_str_mv |
Martins, Inês Soraia Silva, Hugo Filipe Tuchin, Valery Victorovich Oliveira, Luís Manuel |
dc.subject.por.fl_str_mv |
Pancreas tissue Optical properties Scattering coefficient Absorption coefficient Pigment detection |
topic |
Pancreas tissue Optical properties Scattering coefficient Absorption coefficient Pigment detection |
description |
The pancreas is a highly important organ, since it produces insulin and prevents the occurrence of diabetes. Although rare, pancreatic cancer is highly lethal, with a small life expectancy after being diagnosed. The pancreas is one of the organs less studied in the field of biophotonics. With the objective of acquiring information that can be used in the development of future applications to diagnose and treat pancreas diseases, the spectral optical properties of the rabbit pancreas were evaluated in a broad-spectral range, between 200 and 1000 nm. The method used to obtain such optical properties is simple, based almost on direct calculations from spectral measurements. The optical properties obtained show similar wavelength dependencies to the ones obtained for other tissues, but a further analysis on the spectral absorption coefficient showed that the pancreas tissues contain pigments, namely melanin, and lipofuscin. Using a simple calculation, it was possible to retrieve similar contents of these pigments from the absorption spectrum of the pancreas, which indicates that they accumulate in the same proportion as a result of the aging process. Such pigment accumulation was camouflaging the real contents of DNA, hemoglobin, and water, which were precisely evaluated after subtracting the pigment absorption. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022 2022-01-01T00:00:00Z 2023-02-14T09:29:12Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.22/22262 |
url |
http://hdl.handle.net/10400.22/22262 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.3390/photonics9020122 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799131510015524864 |