Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis

Detalhes bibliográficos
Autor(a) principal: Martins, Inês Soraia
Data de Publicação: 2022
Outros Autores: Silva, Hugo Filipe, Tuchin, Valery Victorovich, Oliveira, Luís Manuel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.22/22262
Resumo: The pancreas is a highly important organ, since it produces insulin and prevents the occurrence of diabetes. Although rare, pancreatic cancer is highly lethal, with a small life expectancy after being diagnosed. The pancreas is one of the organs less studied in the field of biophotonics. With the objective of acquiring information that can be used in the development of future applications to diagnose and treat pancreas diseases, the spectral optical properties of the rabbit pancreas were evaluated in a broad-spectral range, between 200 and 1000 nm. The method used to obtain such optical properties is simple, based almost on direct calculations from spectral measurements. The optical properties obtained show similar wavelength dependencies to the ones obtained for other tissues, but a further analysis on the spectral absorption coefficient showed that the pancreas tissues contain pigments, namely melanin, and lipofuscin. Using a simple calculation, it was possible to retrieve similar contents of these pigments from the absorption spectrum of the pancreas, which indicates that they accumulate in the same proportion as a result of the aging process. Such pigment accumulation was camouflaging the real contents of DNA, hemoglobin, and water, which were precisely evaluated after subtracting the pigment absorption.
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spelling Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content AnalysisPancreas tissueOptical propertiesScattering coefficientAbsorption coefficientPigment detectionThe pancreas is a highly important organ, since it produces insulin and prevents the occurrence of diabetes. Although rare, pancreatic cancer is highly lethal, with a small life expectancy after being diagnosed. The pancreas is one of the organs less studied in the field of biophotonics. With the objective of acquiring information that can be used in the development of future applications to diagnose and treat pancreas diseases, the spectral optical properties of the rabbit pancreas were evaluated in a broad-spectral range, between 200 and 1000 nm. The method used to obtain such optical properties is simple, based almost on direct calculations from spectral measurements. The optical properties obtained show similar wavelength dependencies to the ones obtained for other tissues, but a further analysis on the spectral absorption coefficient showed that the pancreas tissues contain pigments, namely melanin, and lipofuscin. Using a simple calculation, it was possible to retrieve similar contents of these pigments from the absorption spectrum of the pancreas, which indicates that they accumulate in the same proportion as a result of the aging process. Such pigment accumulation was camouflaging the real contents of DNA, hemoglobin, and water, which were precisely evaluated after subtracting the pigment absorption.The work of I.S.M. was supported by the Portuguese Science Foundation, grant no. FCTUIDB/ 151528/2021. The work of H.F.S and L.M.O. was supported by the Portuguese Science Foundation, grant No. FCT-UIDB/04730/2020. The work of V.V.T. was supported by a grant under the Decree of the Government of the Russian Federation No. 220 of 09 April 2010 (Agreement No. 075-15-2021-615 of 4 June 2021).MDPIRepositório Científico do Instituto Politécnico do PortoMartins, Inês SoraiaSilva, Hugo FilipeTuchin, Valery VictorovichOliveira, Luís Manuel2023-02-14T09:29:12Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/22262eng10.3390/photonics9020122info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T13:18:52Zoai:recipp.ipp.pt:10400.22/22262Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:42:19.391632Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis
title Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis
spellingShingle Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis
Martins, Inês Soraia
Pancreas tissue
Optical properties
Scattering coefficient
Absorption coefficient
Pigment detection
title_short Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis
title_full Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis
title_fullStr Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis
title_full_unstemmed Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis
title_sort Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis
author Martins, Inês Soraia
author_facet Martins, Inês Soraia
Silva, Hugo Filipe
Tuchin, Valery Victorovich
Oliveira, Luís Manuel
author_role author
author2 Silva, Hugo Filipe
Tuchin, Valery Victorovich
Oliveira, Luís Manuel
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico do Porto
dc.contributor.author.fl_str_mv Martins, Inês Soraia
Silva, Hugo Filipe
Tuchin, Valery Victorovich
Oliveira, Luís Manuel
dc.subject.por.fl_str_mv Pancreas tissue
Optical properties
Scattering coefficient
Absorption coefficient
Pigment detection
topic Pancreas tissue
Optical properties
Scattering coefficient
Absorption coefficient
Pigment detection
description The pancreas is a highly important organ, since it produces insulin and prevents the occurrence of diabetes. Although rare, pancreatic cancer is highly lethal, with a small life expectancy after being diagnosed. The pancreas is one of the organs less studied in the field of biophotonics. With the objective of acquiring information that can be used in the development of future applications to diagnose and treat pancreas diseases, the spectral optical properties of the rabbit pancreas were evaluated in a broad-spectral range, between 200 and 1000 nm. The method used to obtain such optical properties is simple, based almost on direct calculations from spectral measurements. The optical properties obtained show similar wavelength dependencies to the ones obtained for other tissues, but a further analysis on the spectral absorption coefficient showed that the pancreas tissues contain pigments, namely melanin, and lipofuscin. Using a simple calculation, it was possible to retrieve similar contents of these pigments from the absorption spectrum of the pancreas, which indicates that they accumulate in the same proportion as a result of the aging process. Such pigment accumulation was camouflaging the real contents of DNA, hemoglobin, and water, which were precisely evaluated after subtracting the pigment absorption.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022-01-01T00:00:00Z
2023-02-14T09:29:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/22262
url http://hdl.handle.net/10400.22/22262
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.3390/photonics9020122
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv MDPI
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dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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