Development of water-in-oil emulsions as delivery vehicles and testing with a natural antimicrobial extract
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/22304 |
Resumo: | Water-in-oil (W/O) emulsions have high potential for several industrial areas as delivery systems of hydrophilic compounds. In general, they are less studied than oil-in-water (O/W) systems, namely in what concerns the so-called fluid systems, partly due to problems of instability. In this context, this work aimed to produce stable W/O emulsions from a natural oil, sweet almond oil, to be further tested as vehicles of natural hydrophilic extracts, here exemplified with an aqueous cinnamon extract. Firstly, a baseW/O emulsion using a high-water content (40/60, v/v) was developed by testing di erent mixtures of emulsifiers, namely Tween 80 combined with Span 80 or Span 85 at di erent contents. Among the tested systems, the one using a 54/46 (v/v) Span 80/Tween 80 mixture, and subjected to 12 high-pressure homogenizer (HPH) cycles, revealed to be stable up to 6 months, being chosen for the subsequent functionalization tests with cinnamon extract (1.25–5%; w/v; water-basis). The presence of cinnamon extract leaded to changes in the microstructure as well as in the stability. The antimicrobial and antioxidant analysis were evidenced, and a sustained behavior compatible with an extract distribution within the two phases, oil and water, in particular for the higher extract concentration, was observed. |
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Development of water-in-oil emulsions as delivery vehicles and testing with a natural antimicrobial extractCinnamon extractEmulsionsHydrophilic extractsNatural compoundsSweet almond oilWater-in-oilWater-in-oil (W/O) emulsions have high potential for several industrial areas as delivery systems of hydrophilic compounds. In general, they are less studied than oil-in-water (O/W) systems, namely in what concerns the so-called fluid systems, partly due to problems of instability. In this context, this work aimed to produce stable W/O emulsions from a natural oil, sweet almond oil, to be further tested as vehicles of natural hydrophilic extracts, here exemplified with an aqueous cinnamon extract. Firstly, a baseW/O emulsion using a high-water content (40/60, v/v) was developed by testing di erent mixtures of emulsifiers, namely Tween 80 combined with Span 80 or Span 85 at di erent contents. Among the tested systems, the one using a 54/46 (v/v) Span 80/Tween 80 mixture, and subjected to 12 high-pressure homogenizer (HPH) cycles, revealed to be stable up to 6 months, being chosen for the subsequent functionalization tests with cinnamon extract (1.25–5%; w/v; water-basis). The presence of cinnamon extract leaded to changes in the microstructure as well as in the stability. The antimicrobial and antioxidant analysis were evidenced, and a sustained behavior compatible with an extract distribution within the two phases, oil and water, in particular for the higher extract concentration, was observed.Base Funding—UIDB/00690/2020 of CIMO—Mountain Research Center—funded by national funds through FCT/MCTES (PIDDAC). Base Funding—UIDB/50020/2020 of the Associate Laboratory LSRE-LCM—funded by national funds through FCT/MCTES (PIDDAC).Biblioteca Digital do IPBColucci, GiovanaSantamaria-Echart, ArantzazuSilva, Samara CristinaFernandes, Isabel P.Sipoli, Caroline C.Barreiro, M.F.2018-01-19T10:00:00Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/22304engColucci, Giovana; Santamaria-Echart, Arantzazu; Silva, Samara C.; Fernandes, Isabel P.M.; Sipoli, Caroline C.; Barreiro, Maria F. (2020). Development of water-in-oil emulsions as delivery vehicles and testing with a natural antimicrobial extract. Molecules. ISSN1420-3049. 25:9, p. 1-1510.3390/molecules25092105info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:50:01Zoai:bibliotecadigital.ipb.pt:10198/22304Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:13:33.286703Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Development of water-in-oil emulsions as delivery vehicles and testing with a natural antimicrobial extract |
title |
Development of water-in-oil emulsions as delivery vehicles and testing with a natural antimicrobial extract |
spellingShingle |
Development of water-in-oil emulsions as delivery vehicles and testing with a natural antimicrobial extract Colucci, Giovana Cinnamon extract Emulsions Hydrophilic extracts Natural compounds Sweet almond oil Water-in-oil |
title_short |
Development of water-in-oil emulsions as delivery vehicles and testing with a natural antimicrobial extract |
title_full |
Development of water-in-oil emulsions as delivery vehicles and testing with a natural antimicrobial extract |
title_fullStr |
Development of water-in-oil emulsions as delivery vehicles and testing with a natural antimicrobial extract |
title_full_unstemmed |
Development of water-in-oil emulsions as delivery vehicles and testing with a natural antimicrobial extract |
title_sort |
Development of water-in-oil emulsions as delivery vehicles and testing with a natural antimicrobial extract |
author |
Colucci, Giovana |
author_facet |
Colucci, Giovana Santamaria-Echart, Arantzazu Silva, Samara Cristina Fernandes, Isabel P. Sipoli, Caroline C. Barreiro, M.F. |
author_role |
author |
author2 |
Santamaria-Echart, Arantzazu Silva, Samara Cristina Fernandes, Isabel P. Sipoli, Caroline C. Barreiro, M.F. |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Colucci, Giovana Santamaria-Echart, Arantzazu Silva, Samara Cristina Fernandes, Isabel P. Sipoli, Caroline C. Barreiro, M.F. |
dc.subject.por.fl_str_mv |
Cinnamon extract Emulsions Hydrophilic extracts Natural compounds Sweet almond oil Water-in-oil |
topic |
Cinnamon extract Emulsions Hydrophilic extracts Natural compounds Sweet almond oil Water-in-oil |
description |
Water-in-oil (W/O) emulsions have high potential for several industrial areas as delivery systems of hydrophilic compounds. In general, they are less studied than oil-in-water (O/W) systems, namely in what concerns the so-called fluid systems, partly due to problems of instability. In this context, this work aimed to produce stable W/O emulsions from a natural oil, sweet almond oil, to be further tested as vehicles of natural hydrophilic extracts, here exemplified with an aqueous cinnamon extract. Firstly, a baseW/O emulsion using a high-water content (40/60, v/v) was developed by testing di erent mixtures of emulsifiers, namely Tween 80 combined with Span 80 or Span 85 at di erent contents. Among the tested systems, the one using a 54/46 (v/v) Span 80/Tween 80 mixture, and subjected to 12 high-pressure homogenizer (HPH) cycles, revealed to be stable up to 6 months, being chosen for the subsequent functionalization tests with cinnamon extract (1.25–5%; w/v; water-basis). The presence of cinnamon extract leaded to changes in the microstructure as well as in the stability. The antimicrobial and antioxidant analysis were evidenced, and a sustained behavior compatible with an extract distribution within the two phases, oil and water, in particular for the higher extract concentration, was observed. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-19T10:00:00Z 2020 2020-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/22304 |
url |
http://hdl.handle.net/10198/22304 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Colucci, Giovana; Santamaria-Echart, Arantzazu; Silva, Samara C.; Fernandes, Isabel P.M.; Sipoli, Caroline C.; Barreiro, Maria F. (2020). Development of water-in-oil emulsions as delivery vehicles and testing with a natural antimicrobial extract. Molecules. ISSN1420-3049. 25:9, p. 1-15 10.3390/molecules25092105 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799135411847561216 |