Alcohol and free oxygen radicals.

Detalhes bibliográficos
Autor(a) principal: Mira, M L
Data de Publicação: 1993
Outros Autores: Manso, C F
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3075
Resumo: Oxygen free radicals may be generated during ethanol metabolization by cytochrome P450, or due to the formation of xanthine oxidase by ethanol effect on xanthine dehydrogenase. After transformation into acetaldehyde, the metabolism of this compound by xanthine oxidase or by aldehyde oxidase also generates oxygen radicals. We present the hypothesis of a vicious cycle during ethanol metabolization by aldehyde oxidase, which would amplify the process and be responsible for an increased degree of lipid peroxidation.
id RCAP_0328a3fc848618da86ec66f75552b213
oai_identifier_str oai:ojs.www.actamedicaportuguesa.com:article/3075
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Alcohol and free oxygen radicals.Alcool e radicais livres de oxigénio.Oxygen free radicals may be generated during ethanol metabolization by cytochrome P450, or due to the formation of xanthine oxidase by ethanol effect on xanthine dehydrogenase. After transformation into acetaldehyde, the metabolism of this compound by xanthine oxidase or by aldehyde oxidase also generates oxygen radicals. We present the hypothesis of a vicious cycle during ethanol metabolization by aldehyde oxidase, which would amplify the process and be responsible for an increased degree of lipid peroxidation.Oxygen free radicals may be generated during ethanol metabolization by cytochrome P450, or due to the formation of xanthine oxidase by ethanol effect on xanthine dehydrogenase. After transformation into acetaldehyde, the metabolism of this compound by xanthine oxidase or by aldehyde oxidase also generates oxygen radicals. We present the hypothesis of a vicious cycle during ethanol metabolization by aldehyde oxidase, which would amplify the process and be responsible for an increased degree of lipid peroxidation.Ordem dos Médicos1993-05-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3075oai:ojs.www.actamedicaportuguesa.com:article/3075Acta Médica Portuguesa; Vol. 6 No. 5 (1993): Maio; 193-8Acta Médica Portuguesa; Vol. 6 N.º 5 (1993): Maio; 193-81646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3075https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3075/2417Mira, M LManso, C Finfo:eu-repo/semantics/openAccess2022-12-20T11:01:36Zoai:ojs.www.actamedicaportuguesa.com:article/3075Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:18:08.270774Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Alcohol and free oxygen radicals.
Alcool e radicais livres de oxigénio.
title Alcohol and free oxygen radicals.
spellingShingle Alcohol and free oxygen radicals.
Mira, M L
title_short Alcohol and free oxygen radicals.
title_full Alcohol and free oxygen radicals.
title_fullStr Alcohol and free oxygen radicals.
title_full_unstemmed Alcohol and free oxygen radicals.
title_sort Alcohol and free oxygen radicals.
author Mira, M L
author_facet Mira, M L
Manso, C F
author_role author
author2 Manso, C F
author2_role author
dc.contributor.author.fl_str_mv Mira, M L
Manso, C F
description Oxygen free radicals may be generated during ethanol metabolization by cytochrome P450, or due to the formation of xanthine oxidase by ethanol effect on xanthine dehydrogenase. After transformation into acetaldehyde, the metabolism of this compound by xanthine oxidase or by aldehyde oxidase also generates oxygen radicals. We present the hypothesis of a vicious cycle during ethanol metabolization by aldehyde oxidase, which would amplify the process and be responsible for an increased degree of lipid peroxidation.
publishDate 1993
dc.date.none.fl_str_mv 1993-05-30
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3075
oai:ojs.www.actamedicaportuguesa.com:article/3075
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3075
identifier_str_mv oai:ojs.www.actamedicaportuguesa.com:article/3075
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3075
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3075/2417
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 6 No. 5 (1993): Maio; 193-8
Acta Médica Portuguesa; Vol. 6 N.º 5 (1993): Maio; 193-8
1646-0758
0870-399X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799130633546498048

Registros relacionados