Oxygen free-radicals in medicine (2).
Autor(a) principal: | |
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Data de Publicação: | 1989 |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3467 |
Resumo: | Free radicals are highly reactive molecules, and therefore transient, which have an odd number of electrons and are generated in vivo as byproducts of normal metabolism. In this review we survey basic concepts on the chemistry of oxygen free radicals, their cellular sources and the reactions they can undergo. We also discuss the cellular defenses against free radicals induced damage. The disfunction induced by free radicals may thus be a major component of several pathological conditions. The critical role played by free radicals in ageing, carcinogenesis, reperfusion injury and respiratory distress is reviewed. |
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Oxygen free-radicals in medicine (2).Radicais livres do oxigénio em medicina (2. parte).Free radicals are highly reactive molecules, and therefore transient, which have an odd number of electrons and are generated in vivo as byproducts of normal metabolism. In this review we survey basic concepts on the chemistry of oxygen free radicals, their cellular sources and the reactions they can undergo. We also discuss the cellular defenses against free radicals induced damage. The disfunction induced by free radicals may thus be a major component of several pathological conditions. The critical role played by free radicals in ageing, carcinogenesis, reperfusion injury and respiratory distress is reviewed.Free radicals are highly reactive molecules, and therefore transient, which have an odd number of electrons and are generated in vivo as byproducts of normal metabolism. In this review we survey basic concepts on the chemistry of oxygen free radicals, their cellular sources and the reactions they can undergo. We also discuss the cellular defenses against free radicals induced damage. The disfunction induced by free radicals may thus be a major component of several pathological conditions. The critical role played by free radicals in ageing, carcinogenesis, reperfusion injury and respiratory distress is reviewed.Ordem dos Médicos1989-06-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3467oai:ojs.www.actamedicaportuguesa.com:article/3467Acta Médica Portuguesa; Vol. 2 No. 3 (1989): Maio-Junho; 173-7Acta Médica Portuguesa; Vol. 2 N.º 3 (1989): Maio-Junho; 173-71646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3467https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3467/2757Ribeiro, L Minfo:eu-repo/semantics/openAccess2022-12-20T11:02:12Zoai:ojs.www.actamedicaportuguesa.com:article/3467Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:18:21.878838Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Oxygen free-radicals in medicine (2). Radicais livres do oxigénio em medicina (2. parte). |
title |
Oxygen free-radicals in medicine (2). |
spellingShingle |
Oxygen free-radicals in medicine (2). Ribeiro, L M |
title_short |
Oxygen free-radicals in medicine (2). |
title_full |
Oxygen free-radicals in medicine (2). |
title_fullStr |
Oxygen free-radicals in medicine (2). |
title_full_unstemmed |
Oxygen free-radicals in medicine (2). |
title_sort |
Oxygen free-radicals in medicine (2). |
author |
Ribeiro, L M |
author_facet |
Ribeiro, L M |
author_role |
author |
dc.contributor.author.fl_str_mv |
Ribeiro, L M |
description |
Free radicals are highly reactive molecules, and therefore transient, which have an odd number of electrons and are generated in vivo as byproducts of normal metabolism. In this review we survey basic concepts on the chemistry of oxygen free radicals, their cellular sources and the reactions they can undergo. We also discuss the cellular defenses against free radicals induced damage. The disfunction induced by free radicals may thus be a major component of several pathological conditions. The critical role played by free radicals in ageing, carcinogenesis, reperfusion injury and respiratory distress is reviewed. |
publishDate |
1989 |
dc.date.none.fl_str_mv |
1989-06-30 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3467 oai:ojs.www.actamedicaportuguesa.com:article/3467 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3467 |
identifier_str_mv |
oai:ojs.www.actamedicaportuguesa.com:article/3467 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3467 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3467/2757 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 2 No. 3 (1989): Maio-Junho; 173-7 Acta Médica Portuguesa; Vol. 2 N.º 3 (1989): Maio-Junho; 173-7 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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