5-HT2 antagonist activity of 3-aminomethyltetralones

Detalhes bibliográficos
Autor(a) principal: Verde, Ignacio
Data de Publicação: 1991
Outros Autores: Loza, M., Castro, Maria Elena, Orallo, Francisco, Fontenla, José Angel, Calleja, José Maria, Ravina, Enrique, Cortizo, L., Deceballos, M. L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.6/543
Resumo: The affinity of four 3-aminomethyltetralones for 5-HT2 receptors is reported, together with their inhibitory activity against serotonin-induced contractions in rat aorta rings stripped of endothelium. Compound 4, which has a p-fluorobenzoyl-piperidine fragment, exhibited activity similar to that of methysergyde.
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spelling 5-HT2 antagonist activity of 3-aminomethyltetralonesThe affinity of four 3-aminomethyltetralones for 5-HT2 receptors is reported, together with their inhibitory activity against serotonin-induced contractions in rat aorta rings stripped of endothelium. Compound 4, which has a p-fluorobenzoyl-piperidine fragment, exhibited activity similar to that of methysergyde.uBibliorumVerde, IgnacioLoza, M.Castro, Maria ElenaOrallo, FranciscoFontenla, José AngelCalleja, José MariaRavina, EnriqueCortizo, L.Deceballos, M. L.2010-04-28T10:06:45Z19911991-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.6/543enginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-15T09:35:45Zoai:ubibliorum.ubi.pt:10400.6/543Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:42:35.634556Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv 5-HT2 antagonist activity of 3-aminomethyltetralones
title 5-HT2 antagonist activity of 3-aminomethyltetralones
spellingShingle 5-HT2 antagonist activity of 3-aminomethyltetralones
Verde, Ignacio
title_short 5-HT2 antagonist activity of 3-aminomethyltetralones
title_full 5-HT2 antagonist activity of 3-aminomethyltetralones
title_fullStr 5-HT2 antagonist activity of 3-aminomethyltetralones
title_full_unstemmed 5-HT2 antagonist activity of 3-aminomethyltetralones
title_sort 5-HT2 antagonist activity of 3-aminomethyltetralones
author Verde, Ignacio
author_facet Verde, Ignacio
Loza, M.
Castro, Maria Elena
Orallo, Francisco
Fontenla, José Angel
Calleja, José Maria
Ravina, Enrique
Cortizo, L.
Deceballos, M. L.
author_role author
author2 Loza, M.
Castro, Maria Elena
Orallo, Francisco
Fontenla, José Angel
Calleja, José Maria
Ravina, Enrique
Cortizo, L.
Deceballos, M. L.
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv uBibliorum
dc.contributor.author.fl_str_mv Verde, Ignacio
Loza, M.
Castro, Maria Elena
Orallo, Francisco
Fontenla, José Angel
Calleja, José Maria
Ravina, Enrique
Cortizo, L.
Deceballos, M. L.
description The affinity of four 3-aminomethyltetralones for 5-HT2 receptors is reported, together with their inhibitory activity against serotonin-induced contractions in rat aorta rings stripped of endothelium. Compound 4, which has a p-fluorobenzoyl-piperidine fragment, exhibited activity similar to that of methysergyde.
publishDate 1991
dc.date.none.fl_str_mv 1991
1991-01-01T00:00:00Z
2010-04-28T10:06:45Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.6/543
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dc.language.iso.fl_str_mv eng
language eng
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dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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