New antagonist agents of neuropeptide y receptors

Detalhes bibliográficos
Autor(a) principal: Aldana,Ignacio
Data de Publicação: 2000
Outros Autores: Rivero,Isabel, Rivero,Argimiro, Huenchuñir,Patricio, Frigola,Carmen, Alonso,Maria Luisa, Monge,Antonio, Caignard,D. H., Renard,P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422000000600005
Resumo: In the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists will be able to probe the merits of this approach for the treatment of obesity. We report the synthesis and preliminary evaluation of some hydrazide derivatives as antagonists of rNPY.
id SBQ-3_e5fec4cf3367bc56c9bd0446eb56a775
oai_identifier_str oai:scielo:S0100-40422000000600005
network_acronym_str SBQ-3
network_name_str Química Nova (Online)
repository_id_str
spelling New antagonist agents of neuropeptide y receptorsobesityenergy metabolismweight reductionneuropeptide YIn the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists will be able to probe the merits of this approach for the treatment of obesity. We report the synthesis and preliminary evaluation of some hydrazide derivatives as antagonists of rNPY.Sociedade Brasileira de Química2000-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422000000600005Química Nova v.23 n.6 2000reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422000000600005info:eu-repo/semantics/openAccessAldana,IgnacioRivero,IsabelRivero,ArgimiroHuenchuñir,PatricioFrigola,CarmenAlonso,Maria LuisaMonge,AntonioCaignard,D. H.Renard,P.eng2001-01-18T00:00:00Zoai:scielo:S0100-40422000000600005Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2001-01-18T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv New antagonist agents of neuropeptide y receptors
title New antagonist agents of neuropeptide y receptors
spellingShingle New antagonist agents of neuropeptide y receptors
Aldana,Ignacio
obesity
energy metabolism
weight reduction
neuropeptide Y
title_short New antagonist agents of neuropeptide y receptors
title_full New antagonist agents of neuropeptide y receptors
title_fullStr New antagonist agents of neuropeptide y receptors
title_full_unstemmed New antagonist agents of neuropeptide y receptors
title_sort New antagonist agents of neuropeptide y receptors
author Aldana,Ignacio
author_facet Aldana,Ignacio
Rivero,Isabel
Rivero,Argimiro
Huenchuñir,Patricio
Frigola,Carmen
Alonso,Maria Luisa
Monge,Antonio
Caignard,D. H.
Renard,P.
author_role author
author2 Rivero,Isabel
Rivero,Argimiro
Huenchuñir,Patricio
Frigola,Carmen
Alonso,Maria Luisa
Monge,Antonio
Caignard,D. H.
Renard,P.
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Aldana,Ignacio
Rivero,Isabel
Rivero,Argimiro
Huenchuñir,Patricio
Frigola,Carmen
Alonso,Maria Luisa
Monge,Antonio
Caignard,D. H.
Renard,P.
dc.subject.por.fl_str_mv obesity
energy metabolism
weight reduction
neuropeptide Y
topic obesity
energy metabolism
weight reduction
neuropeptide Y
description In the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists will be able to probe the merits of this approach for the treatment of obesity. We report the synthesis and preliminary evaluation of some hydrazide derivatives as antagonists of rNPY.
publishDate 2000
dc.date.none.fl_str_mv 2000-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422000000600005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422000000600005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-40422000000600005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.23 n.6 2000
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
_version_ 1750318101659910144

Registros relacionados