Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis

Detalhes bibliográficos
Autor(a) principal: Bijlsma, L.
Data de Publicação: 2020
Outros Autores: Celma, A., Castiglioni, S., Salgueiro-González, N., Bou-Iserte, L., Baz-Lomba, J.A., Reid, M.J., Dias, M.J., Lopes, A., Matias, J., Pastor-Alcañiz, L., Radonić, J., Turk Sekulic, M., Shine, T., van Nuijs, A.L.N., Hernandez, F., Zuccato, E.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/44451
https://doi.org/10.1016/j.scitotenv.2020.138376
Resumo: The consumption of psychoactive substances is considered a growing problem in many communities. Moreover, new psychoactive substances (NPS) designed as (legal) substitutes to traditional illicit drugs are relatively easily available to the public through e-commerce and retail shops, but there is little knowledge regarding the extent and actual use of these substances. This study aims to gain new and complementary information on NPS and traditional illicit drug use at six music festivals across Europe by investigating wastewater and pooled urine. Samples were collected, between 2015 and 2018, at six music festivals across Europe with approximately 465.000 attendees. Wastewater samples were also collected during a period not coinciding with festivals. A wide-scope screening for 197 NPS, six illicit drugs and known metabolites was applied using different chromatography-mass spectrometric strategies. Several illicit drugs and in total 21 different NPS, mainly synthetic cathinones, phenethylamines and tryptamines, were identified in the samples. Ketamine and the traditional illicit drugs, such as amphetamine-type stimulants, cannabis and cocaine were most abundant and/or frequently detected in the samples collected, suggesting a higher use compared to NPS. The analyses of urine and wastewater is quick and a high number of attendees may be monitored anonymously by analysing only a few samples which allows identifying the local profiles of use of different drugs within a wide panel of psychoactive substances. This approach contributes to the development of an efficient surveillance system which can provide timely insight in the trends of NPS and illicit drugs use.
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spelling Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysisWastewater-based epidemiologyNew psychoactive substancesIllicit drugsPooled urineWastewaterMusic festivalsThe consumption of psychoactive substances is considered a growing problem in many communities. Moreover, new psychoactive substances (NPS) designed as (legal) substitutes to traditional illicit drugs are relatively easily available to the public through e-commerce and retail shops, but there is little knowledge regarding the extent and actual use of these substances. This study aims to gain new and complementary information on NPS and traditional illicit drug use at six music festivals across Europe by investigating wastewater and pooled urine. Samples were collected, between 2015 and 2018, at six music festivals across Europe with approximately 465.000 attendees. Wastewater samples were also collected during a period not coinciding with festivals. A wide-scope screening for 197 NPS, six illicit drugs and known metabolites was applied using different chromatography-mass spectrometric strategies. Several illicit drugs and in total 21 different NPS, mainly synthetic cathinones, phenethylamines and tryptamines, were identified in the samples. Ketamine and the traditional illicit drugs, such as amphetamine-type stimulants, cannabis and cocaine were most abundant and/or frequently detected in the samples collected, suggesting a higher use compared to NPS. The analyses of urine and wastewater is quick and a high number of attendees may be monitored anonymously by analysing only a few samples which allows identifying the local profiles of use of different drugs within a wide panel of psychoactive substances. This approach contributes to the development of an efficient surveillance system which can provide timely insight in the trends of NPS and illicit drugs use.info:eu-repo/semantics/acceptedVersionElsevier2023-04-05T11:05:33Z2023-04-052020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10400.26/44451http://hdl.handle.net/10400.26/44451https://doi.org/10.1016/j.scitotenv.2020.138376engBijlsma, L., Celma, A., Castiglioni, S., Salgueiro-González, N., Bou-Iserte, L., Baz-Lomba, J. A., Reid, M. J., Dias, M. J., Lopes, A., Matias, J., Pastor-Alcañiz, L., Radonić, J., Turk Sekulic, M., Shine, T., van Nuijs, A. L. N., Hernandez, F., & Zuccato, E. (2020). Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis. The Science of the total environment, 725, 1383761879-1026https://www.sciencedirect.com/science/article/pii/S0048969720318891http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessBijlsma, L.Celma, A.Castiglioni, S.Salgueiro-González, N.Bou-Iserte, L.Baz-Lomba, J.A.Reid, M.J.Dias, M.J.Lopes, A.Matias, J.Pastor-Alcañiz, L.Radonić, J.Turk Sekulic, M.Shine, T.van Nuijs, A.L.N.Hernandez, F.Zuccato, E.reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-03T04:22:31Zoai:comum.rcaap.pt:10400.26/44451Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:07:49.880727Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis
title Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis
spellingShingle Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis
Bijlsma, L.
Wastewater-based epidemiology
New psychoactive substances
Illicit drugs
Pooled urine
Wastewater
Music festivals
title_short Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis
title_full Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis
title_fullStr Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis
title_full_unstemmed Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis
title_sort Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis
author Bijlsma, L.
author_facet Bijlsma, L.
Celma, A.
Castiglioni, S.
Salgueiro-González, N.
Bou-Iserte, L.
Baz-Lomba, J.A.
Reid, M.J.
Dias, M.J.
Lopes, A.
Matias, J.
Pastor-Alcañiz, L.
Radonić, J.
Turk Sekulic, M.
Shine, T.
van Nuijs, A.L.N.
Hernandez, F.
Zuccato, E.
author_role author
author2 Celma, A.
Castiglioni, S.
Salgueiro-González, N.
Bou-Iserte, L.
Baz-Lomba, J.A.
Reid, M.J.
Dias, M.J.
Lopes, A.
Matias, J.
Pastor-Alcañiz, L.
Radonić, J.
Turk Sekulic, M.
Shine, T.
van Nuijs, A.L.N.
Hernandez, F.
Zuccato, E.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Bijlsma, L.
Celma, A.
Castiglioni, S.
Salgueiro-González, N.
Bou-Iserte, L.
Baz-Lomba, J.A.
Reid, M.J.
Dias, M.J.
Lopes, A.
Matias, J.
Pastor-Alcañiz, L.
Radonić, J.
Turk Sekulic, M.
Shine, T.
van Nuijs, A.L.N.
Hernandez, F.
Zuccato, E.
dc.subject.por.fl_str_mv Wastewater-based epidemiology
New psychoactive substances
Illicit drugs
Pooled urine
Wastewater
Music festivals
topic Wastewater-based epidemiology
New psychoactive substances
Illicit drugs
Pooled urine
Wastewater
Music festivals
description The consumption of psychoactive substances is considered a growing problem in many communities. Moreover, new psychoactive substances (NPS) designed as (legal) substitutes to traditional illicit drugs are relatively easily available to the public through e-commerce and retail shops, but there is little knowledge regarding the extent and actual use of these substances. This study aims to gain new and complementary information on NPS and traditional illicit drug use at six music festivals across Europe by investigating wastewater and pooled urine. Samples were collected, between 2015 and 2018, at six music festivals across Europe with approximately 465.000 attendees. Wastewater samples were also collected during a period not coinciding with festivals. A wide-scope screening for 197 NPS, six illicit drugs and known metabolites was applied using different chromatography-mass spectrometric strategies. Several illicit drugs and in total 21 different NPS, mainly synthetic cathinones, phenethylamines and tryptamines, were identified in the samples. Ketamine and the traditional illicit drugs, such as amphetamine-type stimulants, cannabis and cocaine were most abundant and/or frequently detected in the samples collected, suggesting a higher use compared to NPS. The analyses of urine and wastewater is quick and a high number of attendees may be monitored anonymously by analysing only a few samples which allows identifying the local profiles of use of different drugs within a wide panel of psychoactive substances. This approach contributes to the development of an efficient surveillance system which can provide timely insight in the trends of NPS and illicit drugs use.
publishDate 2020
dc.date.none.fl_str_mv 2020-01-01T00:00:00Z
2023-04-05T11:05:33Z
2023-04-05
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/44451
http://hdl.handle.net/10400.26/44451
https://doi.org/10.1016/j.scitotenv.2020.138376
url http://hdl.handle.net/10400.26/44451
https://doi.org/10.1016/j.scitotenv.2020.138376
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Bijlsma, L., Celma, A., Castiglioni, S., Salgueiro-González, N., Bou-Iserte, L., Baz-Lomba, J. A., Reid, M. J., Dias, M. J., Lopes, A., Matias, J., Pastor-Alcañiz, L., Radonić, J., Turk Sekulic, M., Shine, T., van Nuijs, A. L. N., Hernandez, F., & Zuccato, E. (2020). Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis. The Science of the total environment, 725, 138376
1879-1026
https://www.sciencedirect.com/science/article/pii/S0048969720318891
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instacron_str RCAAP
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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