Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.gazetamedica.pt/index.php/gazeta/article/view/788 |
Resumo: | Radiotherapy (RT) is a key component of managing head and neck cancer patients. However, despite the emer gence and improvement of new RT techniques, late complications may occur, such as osteoradionecrosis of the mandible (ORNM). The diagnosis is based on clinical/radiological criteria. In the established ORNM, the chronic process does not solve spontaneously, and optimal management still needs to be established. Over the last decades, a broad therapeutic spectrum has been considered, including hyperbaric oxygen therapy (HBOT). Al though, the clinical impact of HBOT varies according to the literature, which is why there is a current controversy regarding its benefits. Further prospective and randomised studies are needed to validate its effectiveness in the ‘real-world’ clinical practice. This article aims to synthesise the existing data, analyse previous studies´ results, identify gaps in knowledge, and discuss ORNM’ management, including a proposal for an algorithm, with a par t icular focus on HBOT. |
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Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature ReviewOxigenoterapia Hiperbárica como Terapêutica Complementar para a Osteorradionecrose da Mandíbula: Fútil ou Útil? - Uma Revisão da LiteraturaHyperbaric OxygenationMandibular Diseases/therapyOsteoradionecrosis/therapyDoenças da Mandíbula/tratamentoOsteorradionecrose/tratamentoOxigenoterapia HiperbáricaRadiotherapy (RT) is a key component of managing head and neck cancer patients. However, despite the emer gence and improvement of new RT techniques, late complications may occur, such as osteoradionecrosis of the mandible (ORNM). The diagnosis is based on clinical/radiological criteria. In the established ORNM, the chronic process does not solve spontaneously, and optimal management still needs to be established. Over the last decades, a broad therapeutic spectrum has been considered, including hyperbaric oxygen therapy (HBOT). Al though, the clinical impact of HBOT varies according to the literature, which is why there is a current controversy regarding its benefits. Further prospective and randomised studies are needed to validate its effectiveness in the ‘real-world’ clinical practice. This article aims to synthesise the existing data, analyse previous studies´ results, identify gaps in knowledge, and discuss ORNM’ management, including a proposal for an algorithm, with a par t icular focus on HBOT.A radioterapia (RT) é uma componente fundamental do tratamento multimodal dos doentes com cancro da cabeça e pescoço. Contudo, apesar do surgimento e aperfeiçoamento das técnicas de RT, podem ocorrer com plicações tardias, como a osteorradionecrose da mandíbula (ORNM). O seu diagnóstico é baseado em critérios clínicos/radiológicos. Na ORNM estabelecida, o processo crónico não resolve espontaneamente e, até à data, não foi estabelecida uma abordagem terapêutica ótima. Nas últimas décadas foram considerados diversos tipos de tratamento, incluído a oxigenoterapia hiperbárica (HBOT). Contudo, o impacto clínico da HBOT varia de acordo com a literatura, o que gera controvérsia em relação aos seus benefícios. Estudos prospetivos e aleatorizados adicionais são essenciais para validar a eficácia deste tratamento na prática clínica. O objetivo deste artigo é sin tetizar os dados existentes, analisar os resultados de estudos prévios, identificar lacunas no conhecimento e dis cutir a abordagem da ORNM, incluindo uma proposta de algoritmo terapêutico com especial enfoque na HBOT.CUF Academic Center2024-02-28info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.gazetamedica.pt/index.php/gazeta/article/view/788Gazeta Médica; Ahead of PrintGazeta Médica; Ahead of Print2184-06282183-8135reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.gazetamedica.pt/index.php/gazeta/article/view/788https://www.gazetamedica.pt/index.php/gazeta/article/view/788/482Copyright (c) 2015 Gazeta Médicainfo:eu-repo/semantics/openAccessAlpuim Costa, DiogoArana Ribeiro, JoanaD'Espiney Amaro, Carla2024-03-09T04:46:59Zoai:ojs.pkp.sfu.ca:article/788Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:11:53.859160Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review Oxigenoterapia Hiperbárica como Terapêutica Complementar para a Osteorradionecrose da Mandíbula: Fútil ou Útil? - Uma Revisão da Literatura |
title |
Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review |
spellingShingle |
Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review Alpuim Costa, Diogo Hyperbaric Oxygenation Mandibular Diseases/therapy Osteoradionecrosis/therapy Doenças da Mandíbula/tratamento Osteorradionecrose/tratamento Oxigenoterapia Hiperbárica |
title_short |
Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review |
title_full |
Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review |
title_fullStr |
Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review |
title_full_unstemmed |
Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review |
title_sort |
Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review |
author |
Alpuim Costa, Diogo |
author_facet |
Alpuim Costa, Diogo Arana Ribeiro, Joana D'Espiney Amaro, Carla |
author_role |
author |
author2 |
Arana Ribeiro, Joana D'Espiney Amaro, Carla |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Alpuim Costa, Diogo Arana Ribeiro, Joana D'Espiney Amaro, Carla |
dc.subject.por.fl_str_mv |
Hyperbaric Oxygenation Mandibular Diseases/therapy Osteoradionecrosis/therapy Doenças da Mandíbula/tratamento Osteorradionecrose/tratamento Oxigenoterapia Hiperbárica |
topic |
Hyperbaric Oxygenation Mandibular Diseases/therapy Osteoradionecrosis/therapy Doenças da Mandíbula/tratamento Osteorradionecrose/tratamento Oxigenoterapia Hiperbárica |
description |
Radiotherapy (RT) is a key component of managing head and neck cancer patients. However, despite the emer gence and improvement of new RT techniques, late complications may occur, such as osteoradionecrosis of the mandible (ORNM). The diagnosis is based on clinical/radiological criteria. In the established ORNM, the chronic process does not solve spontaneously, and optimal management still needs to be established. Over the last decades, a broad therapeutic spectrum has been considered, including hyperbaric oxygen therapy (HBOT). Al though, the clinical impact of HBOT varies according to the literature, which is why there is a current controversy regarding its benefits. Further prospective and randomised studies are needed to validate its effectiveness in the ‘real-world’ clinical practice. This article aims to synthesise the existing data, analyse previous studies´ results, identify gaps in knowledge, and discuss ORNM’ management, including a proposal for an algorithm, with a par t icular focus on HBOT. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-02-28 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.gazetamedica.pt/index.php/gazeta/article/view/788 |
url |
https://www.gazetamedica.pt/index.php/gazeta/article/view/788 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.gazetamedica.pt/index.php/gazeta/article/view/788 https://www.gazetamedica.pt/index.php/gazeta/article/view/788/482 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2015 Gazeta Médica info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2015 Gazeta Médica |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
CUF Academic Center |
publisher.none.fl_str_mv |
CUF Academic Center |
dc.source.none.fl_str_mv |
Gazeta Médica; Ahead of Print Gazeta Médica; Ahead of Print 2184-0628 2183-8135 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799137768912191488 |