Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review

Detalhes bibliográficos
Autor(a) principal: Alpuim Costa, Diogo
Data de Publicação: 2024
Outros Autores: Arana Ribeiro, Joana, D'Espiney Amaro, Carla
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.gazetamedica.pt/index.php/gazeta/article/view/788
Resumo: Radiotherapy (RT) is a key component of managing head and neck cancer patients. However, despite the emer gence and improvement of new RT techniques, late complications may occur, such as osteoradionecrosis of the mandible (ORNM). The diagnosis is based on clinical/radiological criteria. In the established ORNM, the chronic process does not solve spontaneously, and optimal management still needs to be established. Over the last decades, a broad therapeutic spectrum has been considered, including hyperbaric oxygen therapy (HBOT). Al though, the clinical impact of HBOT varies according to the literature, which is why there is a current controversy regarding its benefits. Further prospective and randomised studies are needed to validate its effectiveness in the ‘real-world’ clinical practice. This article aims to synthesise the existing data, analyse previous studies´ results, identify gaps in knowledge, and discuss ORNM’ management, including a proposal for an algorithm, with a par t icular focus on HBOT.
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spelling Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature ReviewOxigenoterapia Hiperbárica como Terapêutica Complementar para a Osteorradionecrose da Mandíbula: Fútil ou Útil? - Uma Revisão da LiteraturaHyperbaric OxygenationMandibular Diseases/therapyOsteoradionecrosis/therapyDoenças da Mandíbula/tratamentoOsteorradionecrose/tratamentoOxigenoterapia HiperbáricaRadiotherapy (RT) is a key component of managing head and neck cancer patients. However, despite the emer gence and improvement of new RT techniques, late complications may occur, such as osteoradionecrosis of the mandible (ORNM). The diagnosis is based on clinical/radiological criteria. In the established ORNM, the chronic process does not solve spontaneously, and optimal management still needs to be established. Over the last decades, a broad therapeutic spectrum has been considered, including hyperbaric oxygen therapy (HBOT). Al though, the clinical impact of HBOT varies according to the literature, which is why there is a current controversy regarding its benefits. Further prospective and randomised studies are needed to validate its effectiveness in the ‘real-world’ clinical practice. This article aims to synthesise the existing data, analyse previous studies´ results, identify gaps in knowledge, and discuss ORNM’ management, including a proposal for an algorithm, with a par t icular focus on HBOT.A radioterapia (RT) é uma componente fundamental do tratamento multimodal dos doentes com cancro da cabeça e pescoço. Contudo, apesar do surgimento e aperfeiçoamento das técnicas de RT, podem ocorrer com plicações tardias, como a osteorradionecrose da mandíbula (ORNM). O seu diagnóstico é baseado em critérios clínicos/radiológicos. Na ORNM estabelecida, o processo crónico não resolve espontaneamente e, até à data, não foi estabelecida uma abordagem terapêutica ótima. Nas últimas décadas foram considerados diversos tipos de tratamento, incluído a oxigenoterapia hiperbárica (HBOT). Contudo, o impacto clínico da HBOT varia de acordo com a literatura, o que gera controvérsia em relação aos seus benefícios. Estudos prospetivos e aleatorizados adicionais são essenciais para validar a eficácia deste tratamento na prática clínica. O objetivo deste artigo é sin tetizar os dados existentes, analisar os resultados de estudos prévios, identificar lacunas no conhecimento e dis cutir a abordagem da ORNM, incluindo uma proposta de algoritmo terapêutico com especial enfoque na HBOT.CUF Academic Center2024-02-28info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.gazetamedica.pt/index.php/gazeta/article/view/788Gazeta Médica; Ahead of PrintGazeta Médica; Ahead of Print2184-06282183-8135reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.gazetamedica.pt/index.php/gazeta/article/view/788https://www.gazetamedica.pt/index.php/gazeta/article/view/788/482Copyright (c) 2015 Gazeta Médicainfo:eu-repo/semantics/openAccessAlpuim Costa, DiogoArana Ribeiro, JoanaD'Espiney Amaro, Carla2024-03-09T04:46:59Zoai:ojs.pkp.sfu.ca:article/788Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:11:53.859160Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review
Oxigenoterapia Hiperbárica como Terapêutica Complementar para a Osteorradionecrose da Mandíbula: Fútil ou Útil? - Uma Revisão da Literatura
title Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review
spellingShingle Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review
Alpuim Costa, Diogo
Hyperbaric Oxygenation
Mandibular Diseases/therapy
Osteoradionecrosis/therapy
Doenças da Mandíbula/tratamento
Osteorradionecrose/tratamento
Oxigenoterapia Hiperbárica
title_short Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review
title_full Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review
title_fullStr Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review
title_full_unstemmed Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review
title_sort Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review
author Alpuim Costa, Diogo
author_facet Alpuim Costa, Diogo
Arana Ribeiro, Joana
D'Espiney Amaro, Carla
author_role author
author2 Arana Ribeiro, Joana
D'Espiney Amaro, Carla
author2_role author
author
dc.contributor.author.fl_str_mv Alpuim Costa, Diogo
Arana Ribeiro, Joana
D'Espiney Amaro, Carla
dc.subject.por.fl_str_mv Hyperbaric Oxygenation
Mandibular Diseases/therapy
Osteoradionecrosis/therapy
Doenças da Mandíbula/tratamento
Osteorradionecrose/tratamento
Oxigenoterapia Hiperbárica
topic Hyperbaric Oxygenation
Mandibular Diseases/therapy
Osteoradionecrosis/therapy
Doenças da Mandíbula/tratamento
Osteorradionecrose/tratamento
Oxigenoterapia Hiperbárica
description Radiotherapy (RT) is a key component of managing head and neck cancer patients. However, despite the emer gence and improvement of new RT techniques, late complications may occur, such as osteoradionecrosis of the mandible (ORNM). The diagnosis is based on clinical/radiological criteria. In the established ORNM, the chronic process does not solve spontaneously, and optimal management still needs to be established. Over the last decades, a broad therapeutic spectrum has been considered, including hyperbaric oxygen therapy (HBOT). Al though, the clinical impact of HBOT varies according to the literature, which is why there is a current controversy regarding its benefits. Further prospective and randomised studies are needed to validate its effectiveness in the ‘real-world’ clinical practice. This article aims to synthesise the existing data, analyse previous studies´ results, identify gaps in knowledge, and discuss ORNM’ management, including a proposal for an algorithm, with a par t icular focus on HBOT.
publishDate 2024
dc.date.none.fl_str_mv 2024-02-28
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.gazetamedica.pt/index.php/gazeta/article/view/788
url https://www.gazetamedica.pt/index.php/gazeta/article/view/788
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.gazetamedica.pt/index.php/gazeta/article/view/788
https://www.gazetamedica.pt/index.php/gazeta/article/view/788/482
dc.rights.driver.fl_str_mv Copyright (c) 2015 Gazeta Médica
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2015 Gazeta Médica
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv CUF Academic Center
publisher.none.fl_str_mv CUF Academic Center
dc.source.none.fl_str_mv Gazeta Médica; Ahead of Print
Gazeta Médica; Ahead of Print
2184-0628
2183-8135
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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