Virtual Reality Cognitive Training Among Individuals With Alcohol Use Disorder Undergoing Residential Treatment

Detalhes bibliográficos
Autor(a) principal: Gamito, Pedro
Data de Publicação: 2021
Outros Autores: Oliveira, Jorge, Matias, Marcelo Alexandre Cabaça, Cunha, Elsa Alexandra Pinto Ribeiro da, Brito, Rodrigo, Lopes, Paulo Jorge Ferreira, Deus, Alberto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10437/12428
Resumo: Background: Alcoholusedisorder(AUD)hasbeenassociatedwithdiversephysicalandmentalmorbidities.Amongthemain consequences of chronic and excessive alcohol use are cognitive and executive deficits. Some of these deficits may be reversed in specific cognitive and executive domains with behavioral approaches consisting of cognitive training. The advent of computer-based interventions may leverage these improvements, but randomized controlled trials (RCTs) of digital interactive-based interventions are still scarce. Objective: The aim of this study is to explore whether a cognitive training approach using VR exercises based on activities of daily living is feasible for improving the cognitive function of patients with AUD undergoing residential treatment, as well as to estimate the effect size for this intervention to power future definitive RCTs. Methods: This study consisted of a two-arm pilot RCT with a sample of 36 individuals recovering from AUD in a therapeutic community; experimental group participants received a therapist-guided, VR-based cognitive training intervention combined with treatment as usual, and control group participants received treatment as usual without cognitive training. A comprehensive neuropsychological battery of tests was used both at pre- and postassessments, including measurement of global cognition, executive functions, attention, visual memory, and cognitive flexibility. Results: In order to control for potential effects of global cognition and executive functions at baseline, these domains were controlled for in the statistical analysis for each individual outcome. Results indicate intervention effects on attention in two out of five outcomes and on cognitive flexibility in two out of six outcomes, with effect sizes in significant comparisons being larger for attention than for cognitive flexibility. Patient retention in cognitive training was high, in line with previous studies. Conclusions: Overall, the data suggest that VR-based cognitive training results in specific contributions to improving attention ability and cognitive flexibility of patients recovering from AUD. Trial Registration: ClinicalTrials.gov NCT04505345; https://clinicaltrials.gov/show/NCT04505345
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spelling Virtual Reality Cognitive Training Among Individuals With Alcohol Use Disorder Undergoing Residential TreatmentALCOHOL USE DESORDERCOGNITIVE TRAININGVIRTUAL REALITYPSYCHOLOGYPSICOLOGIAPERTURBAÇÃO DO USO DE ÁLCOOLTREINO COGNITIVOREALIDADE VIRTUALBackground: Alcoholusedisorder(AUD)hasbeenassociatedwithdiversephysicalandmentalmorbidities.Amongthemain consequences of chronic and excessive alcohol use are cognitive and executive deficits. Some of these deficits may be reversed in specific cognitive and executive domains with behavioral approaches consisting of cognitive training. The advent of computer-based interventions may leverage these improvements, but randomized controlled trials (RCTs) of digital interactive-based interventions are still scarce. Objective: The aim of this study is to explore whether a cognitive training approach using VR exercises based on activities of daily living is feasible for improving the cognitive function of patients with AUD undergoing residential treatment, as well as to estimate the effect size for this intervention to power future definitive RCTs. Methods: This study consisted of a two-arm pilot RCT with a sample of 36 individuals recovering from AUD in a therapeutic community; experimental group participants received a therapist-guided, VR-based cognitive training intervention combined with treatment as usual, and control group participants received treatment as usual without cognitive training. A comprehensive neuropsychological battery of tests was used both at pre- and postassessments, including measurement of global cognition, executive functions, attention, visual memory, and cognitive flexibility. Results: In order to control for potential effects of global cognition and executive functions at baseline, these domains were controlled for in the statistical analysis for each individual outcome. Results indicate intervention effects on attention in two out of five outcomes and on cognitive flexibility in two out of six outcomes, with effect sizes in significant comparisons being larger for attention than for cognitive flexibility. Patient retention in cognitive training was high, in line with previous studies. Conclusions: Overall, the data suggest that VR-based cognitive training results in specific contributions to improving attention ability and cognitive flexibility of patients recovering from AUD. Trial Registration: ClinicalTrials.gov NCT04505345; https://clinicaltrials.gov/show/NCT045053452022-01-20T15:32:14Z2021-01-01T00:00:00Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10437/12428engGamito, PedroOliveira, JorgeMatias, Marcelo Alexandre CabaçaCunha, Elsa Alexandra Pinto Ribeiro daBrito, RodrigoLopes, Paulo Jorge FerreiraDeus, Albertoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-09T14:05:05Zoai:recil.ensinolusofona.pt:10437/12428Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:12:55.119903Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Virtual Reality Cognitive Training Among Individuals With Alcohol Use Disorder Undergoing Residential Treatment
title Virtual Reality Cognitive Training Among Individuals With Alcohol Use Disorder Undergoing Residential Treatment
spellingShingle Virtual Reality Cognitive Training Among Individuals With Alcohol Use Disorder Undergoing Residential Treatment
Gamito, Pedro
ALCOHOL USE DESORDER
COGNITIVE TRAINING
VIRTUAL REALITY
PSYCHOLOGY
PSICOLOGIA
PERTURBAÇÃO DO USO DE ÁLCOOL
TREINO COGNITIVO
REALIDADE VIRTUAL
title_short Virtual Reality Cognitive Training Among Individuals With Alcohol Use Disorder Undergoing Residential Treatment
title_full Virtual Reality Cognitive Training Among Individuals With Alcohol Use Disorder Undergoing Residential Treatment
title_fullStr Virtual Reality Cognitive Training Among Individuals With Alcohol Use Disorder Undergoing Residential Treatment
title_full_unstemmed Virtual Reality Cognitive Training Among Individuals With Alcohol Use Disorder Undergoing Residential Treatment
title_sort Virtual Reality Cognitive Training Among Individuals With Alcohol Use Disorder Undergoing Residential Treatment
author Gamito, Pedro
author_facet Gamito, Pedro
Oliveira, Jorge
Matias, Marcelo Alexandre Cabaça
Cunha, Elsa Alexandra Pinto Ribeiro da
Brito, Rodrigo
Lopes, Paulo Jorge Ferreira
Deus, Alberto
author_role author
author2 Oliveira, Jorge
Matias, Marcelo Alexandre Cabaça
Cunha, Elsa Alexandra Pinto Ribeiro da
Brito, Rodrigo
Lopes, Paulo Jorge Ferreira
Deus, Alberto
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gamito, Pedro
Oliveira, Jorge
Matias, Marcelo Alexandre Cabaça
Cunha, Elsa Alexandra Pinto Ribeiro da
Brito, Rodrigo
Lopes, Paulo Jorge Ferreira
Deus, Alberto
dc.subject.por.fl_str_mv ALCOHOL USE DESORDER
COGNITIVE TRAINING
VIRTUAL REALITY
PSYCHOLOGY
PSICOLOGIA
PERTURBAÇÃO DO USO DE ÁLCOOL
TREINO COGNITIVO
REALIDADE VIRTUAL
topic ALCOHOL USE DESORDER
COGNITIVE TRAINING
VIRTUAL REALITY
PSYCHOLOGY
PSICOLOGIA
PERTURBAÇÃO DO USO DE ÁLCOOL
TREINO COGNITIVO
REALIDADE VIRTUAL
description Background: Alcoholusedisorder(AUD)hasbeenassociatedwithdiversephysicalandmentalmorbidities.Amongthemain consequences of chronic and excessive alcohol use are cognitive and executive deficits. Some of these deficits may be reversed in specific cognitive and executive domains with behavioral approaches consisting of cognitive training. The advent of computer-based interventions may leverage these improvements, but randomized controlled trials (RCTs) of digital interactive-based interventions are still scarce. Objective: The aim of this study is to explore whether a cognitive training approach using VR exercises based on activities of daily living is feasible for improving the cognitive function of patients with AUD undergoing residential treatment, as well as to estimate the effect size for this intervention to power future definitive RCTs. Methods: This study consisted of a two-arm pilot RCT with a sample of 36 individuals recovering from AUD in a therapeutic community; experimental group participants received a therapist-guided, VR-based cognitive training intervention combined with treatment as usual, and control group participants received treatment as usual without cognitive training. A comprehensive neuropsychological battery of tests was used both at pre- and postassessments, including measurement of global cognition, executive functions, attention, visual memory, and cognitive flexibility. Results: In order to control for potential effects of global cognition and executive functions at baseline, these domains were controlled for in the statistical analysis for each individual outcome. Results indicate intervention effects on attention in two out of five outcomes and on cognitive flexibility in two out of six outcomes, with effect sizes in significant comparisons being larger for attention than for cognitive flexibility. Patient retention in cognitive training was high, in line with previous studies. Conclusions: Overall, the data suggest that VR-based cognitive training results in specific contributions to improving attention ability and cognitive flexibility of patients recovering from AUD. Trial Registration: ClinicalTrials.gov NCT04505345; https://clinicaltrials.gov/show/NCT04505345
publishDate 2021
dc.date.none.fl_str_mv 2021-01-01T00:00:00Z
2021-01-01
2022-01-20T15:32:14Z
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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