A Core Outcome Set for nutritional intervention studies in older adults with malnutrition and those at risk

Detalhes bibliográficos
Autor(a) principal: Visser, Marjolein
Data de Publicação: 2023
Outros Autores: Mendonça, Nuno, Avgerinou, Christina, Cavdar, Sibel, Cederholm, Tommy, Cruz-Jentoft, Alfonso J., Kiesswetter, Eva, Siebentritt, Hanna M., Sieber, Cornel, Torbahn, Gabriel, Volkert, Dorothee
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/151938
Resumo: Funding: No funding was received for this project. NM was funded by the Fundação para a Ciência e a Tecnologia (2021.00745.CEECIND)
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spelling A Core Outcome Set for nutritional intervention studies in older adults with malnutrition and those at riska study protocolAgedCore Outcome SetDelphi techniqueEndpoint determinationMalnutritionMeta-analysisRandomized controlled trialsReviewGeriatrics and GerontologySDG 2 - Zero HungerFunding: No funding was received for this project. NM was funded by the Fundação para a Ciência e a Tecnologia (2021.00745.CEECIND)BACKGROUND: Malnutrition (i.e., protein-energy malnutrition) in older adults has severe negative clinical consequences, emphasizing the need for effective treatments. Many, often small, randomized controlled trials (RCTs) testing the effectiveness of nutritional interventions for the treatment of malnutrition showed mixed results and a need for meta-analyses and data pooling has been expressed. However, evidence synthesis is hampered by the wide variety of outcomes and their method of assessment in previous RCTs. This paper describes the protocol for developing a Core Outcome Set (COS) for nutritional intervention studies in older adults with malnutrition and those at risk. METHODS: The project consists of five phases. The first phase consists of a scoping review to identify frequently used outcomes in published RCTs and select additional patient-reported outcomes. The second phase includes a modified Delphi Survey involving experienced researchers and health care professionals working in the field of malnutrition in older adults, followed by the third phase consisting of a consensus meeting to discuss and agree what critical outcomes need to be included in the COS. The fourth phase will determine how each COS outcome should be measured based on a systematic literature review and a second consensus meeting. This will be followed by a dissemination and implementation phase. Patient and Public Involvement (PPI) representatives will contribute to study design, oversight, consensus, and dissemination. CONCLUSIONS: The result of this project is a COS that should be included in any RCT evaluating the effect of nutritional interventions in older adults with malnutrition and those at risk. This COS will facilitate comparison of RCT results, will increase efficient use of research resources and will reduce bias due to measurement of the outcome and publication bias. Ultimately, the COS will support clinical decision making by identifying the most effective approaches for treating and preventing malnutrition in older adults.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Comprehensive Health Research Centre (CHRC) - pólo NMSRUNVisser, MarjoleinMendonça, NunoAvgerinou, ChristinaCavdar, SibelCederholm, TommyCruz-Jentoft, Alfonso J.Kiesswetter, EvaSiebentritt, Hanna M.Sieber, CornelTorbahn, GabrielVolkert, Dorothee2023-04-19T22:23:29Z2023-04-062023-04-06T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1application/pdfhttp://hdl.handle.net/10362/151938eng1471-2318PURE: 58473375https://doi.org/10.1186/s12877-023-03832-2info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:34:17Zoai:run.unl.pt:10362/151938Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:54:43.827543Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A Core Outcome Set for nutritional intervention studies in older adults with malnutrition and those at risk
a study protocol
title A Core Outcome Set for nutritional intervention studies in older adults with malnutrition and those at risk
spellingShingle A Core Outcome Set for nutritional intervention studies in older adults with malnutrition and those at risk
Visser, Marjolein
Aged
Core Outcome Set
Delphi technique
Endpoint determination
Malnutrition
Meta-analysis
Randomized controlled trials
Review
Geriatrics and Gerontology
SDG 2 - Zero Hunger
title_short A Core Outcome Set for nutritional intervention studies in older adults with malnutrition and those at risk
title_full A Core Outcome Set for nutritional intervention studies in older adults with malnutrition and those at risk
title_fullStr A Core Outcome Set for nutritional intervention studies in older adults with malnutrition and those at risk
title_full_unstemmed A Core Outcome Set for nutritional intervention studies in older adults with malnutrition and those at risk
title_sort A Core Outcome Set for nutritional intervention studies in older adults with malnutrition and those at risk
author Visser, Marjolein
author_facet Visser, Marjolein
Mendonça, Nuno
Avgerinou, Christina
Cavdar, Sibel
Cederholm, Tommy
Cruz-Jentoft, Alfonso J.
Kiesswetter, Eva
Siebentritt, Hanna M.
Sieber, Cornel
Torbahn, Gabriel
Volkert, Dorothee
author_role author
author2 Mendonça, Nuno
Avgerinou, Christina
Cavdar, Sibel
Cederholm, Tommy
Cruz-Jentoft, Alfonso J.
Kiesswetter, Eva
Siebentritt, Hanna M.
Sieber, Cornel
Torbahn, Gabriel
Volkert, Dorothee
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
Comprehensive Health Research Centre (CHRC) - pólo NMS
RUN
dc.contributor.author.fl_str_mv Visser, Marjolein
Mendonça, Nuno
Avgerinou, Christina
Cavdar, Sibel
Cederholm, Tommy
Cruz-Jentoft, Alfonso J.
Kiesswetter, Eva
Siebentritt, Hanna M.
Sieber, Cornel
Torbahn, Gabriel
Volkert, Dorothee
dc.subject.por.fl_str_mv Aged
Core Outcome Set
Delphi technique
Endpoint determination
Malnutrition
Meta-analysis
Randomized controlled trials
Review
Geriatrics and Gerontology
SDG 2 - Zero Hunger
topic Aged
Core Outcome Set
Delphi technique
Endpoint determination
Malnutrition
Meta-analysis
Randomized controlled trials
Review
Geriatrics and Gerontology
SDG 2 - Zero Hunger
description Funding: No funding was received for this project. NM was funded by the Fundação para a Ciência e a Tecnologia (2021.00745.CEECIND)
publishDate 2023
dc.date.none.fl_str_mv 2023-04-19T22:23:29Z
2023-04-06
2023-04-06T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/151938
url http://hdl.handle.net/10362/151938
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1471-2318
PURE: 58473375
https://doi.org/10.1186/s12877-023-03832-2
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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