Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030

Detalhes bibliográficos
Autor(a) principal: Zare Jeddi, Maryam
Data de Publicação: 2022
Outros Autores: Hopf, Nancy B., Louro, Henriqueta, Viegas, Susana, Galea, Karen S., Pasanen-Kase, Robert, Santonen, Tiina, Mustieles, Vicente, Fernandez, Mariana F., Verhagen, Hans, Bopp, Stephanie K., Antignac, Jean Philippe, David, Arthur, Mol, Hans, Barouki, Robert, Audouze, Karine, Duca, Radu-Corneliu, Fantke, Peter, Scheepers, Paul, Ghosh, Manosij, Van Nieuwenhuyse, An, Lobo Vicente, Joana, Trier, Xenia, Rambaud, Loïc, Fillol, Clémence, Denys, Sebastien, Conrad, André, Kolossa-Gehring, Marike, Paini, Alicia, Arnot, Jon, Schulze, Florian, Jones, Kate, Sepai, Ovnair, Ali, Imran, Brennan, Lorraine, Benfenati, Emilio, Cubadda, Francesco, Mantovani, Alberto, Bartonova, Alena, Connolly, Alison, Slobodnik, Jaroslav, Bruinen de Bruin, Yuri, van Klaveren, Jacob, Palmen, Nicole, Dirven, Hubert, Husøy, Trine, Thomsen, Cathrine, Virgolino, Ana, Röösli, Martin, Gant, Tim, von Goetz, Natalie, Bessems, Jos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/8297
Resumo: Human biomonitoring (HBM) is a crucial approach for exposure assessment, as emphasised in the European Commission’s Chemicals Strategy for Sustainability (CSS). HBM can help to improve chemical policies in five major key areas: (1) assessing internal and aggregate exposure in different target populations; 2) assessing exposure to chemicals across life stages; (3) assessing combined exposure to multiple chemicals (mixtures); (4) bridging regulatory silos on aggregate exposure; and (5) enhancing the effectiveness of risk management measures. In this strategy paper we propose a vision and a strategy for the use of HBM in chemical regulations and public health policy in Europe and beyond. We outline six strategic objectives and a roadmap to further strengthen HBM approaches and increase their implementation in the regulatory risk assessment of chemicals to enhance our understanding of exposure and health impacts, enabling timely and targeted policy interventions and risk management. These strategic objectives are: 1) further development of sampling strategies and sample preparation; 2) further development of chemical-analytical HBM methods; 3) improving harmonisation throughout the HBM research life cycle; 4) further development of quality control / quality assurance throughout the HBM research life cycle; 5) obtain sustained funding and reinforcement by legislation; and 6) extend target-specific communication with scientists, policymakers, citizens and other stakeholders. HBM approaches are essential in risk assessment to address scientific, regulatory and societal challenges. HBM requires full and strong support from the scientific and regulatory domain to reach its full potential in public and occupational health assessment and in regulatory decision-making.
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spelling Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030Human BiomonitoringEnvironmental GenotoxicityChemicals MixturesData GovernanceZero Pollution AmbitionOne Substance-one AssessmentCircular EconomyEuropean Exposure Science StrategyEuropeGenotoxicidade AmbientalHuman biomonitoring (HBM) is a crucial approach for exposure assessment, as emphasised in the European Commission’s Chemicals Strategy for Sustainability (CSS). HBM can help to improve chemical policies in five major key areas: (1) assessing internal and aggregate exposure in different target populations; 2) assessing exposure to chemicals across life stages; (3) assessing combined exposure to multiple chemicals (mixtures); (4) bridging regulatory silos on aggregate exposure; and (5) enhancing the effectiveness of risk management measures. In this strategy paper we propose a vision and a strategy for the use of HBM in chemical regulations and public health policy in Europe and beyond. We outline six strategic objectives and a roadmap to further strengthen HBM approaches and increase their implementation in the regulatory risk assessment of chemicals to enhance our understanding of exposure and health impacts, enabling timely and targeted policy interventions and risk management. These strategic objectives are: 1) further development of sampling strategies and sample preparation; 2) further development of chemical-analytical HBM methods; 3) improving harmonisation throughout the HBM research life cycle; 4) further development of quality control / quality assurance throughout the HBM research life cycle; 5) obtain sustained funding and reinforcement by legislation; and 6) extend target-specific communication with scientists, policymakers, citizens and other stakeholders. HBM approaches are essential in risk assessment to address scientific, regulatory and societal challenges. HBM requires full and strong support from the scientific and regulatory domain to reach its full potential in public and occupational health assessment and in regulatory decision-making.ElsevierRepositório Científico do Instituto Nacional de SaúdeZare Jeddi, MaryamHopf, Nancy B.Louro, HenriquetaViegas, SusanaGalea, Karen S.Pasanen-Kase, RobertSantonen, TiinaMustieles, VicenteFernandez, Mariana F.Verhagen, HansBopp, Stephanie K.Antignac, Jean PhilippeDavid, ArthurMol, HansBarouki, RobertAudouze, KarineDuca, Radu-CorneliuFantke, PeterScheepers, PaulGhosh, ManosijVan Nieuwenhuyse, AnLobo Vicente, JoanaTrier, XeniaRambaud, LoïcFillol, ClémenceDenys, SebastienConrad, AndréKolossa-Gehring, MarikePaini, AliciaArnot, JonSchulze, FlorianJones, KateSepai, OvnairAli, ImranBrennan, LorraineBenfenati, EmilioCubadda, FrancescoMantovani, AlbertoBartonova, AlenaConnolly, AlisonSlobodnik, JaroslavBruinen de Bruin, Yurivan Klaveren, JacobPalmen, NicoleDirven, HubertHusøy, TrineThomsen, CathrineVirgolino, AnaRöösli, MartinGant, Timvon Goetz, NatalieBessems, Jos2022-11-02T14:40:03Z2022-08-282022-08-28T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/8297engEnviron Int. 2022 Aug 28;168:107476. doi: 10.1016/j.envint.2022.107476. Online ahead of print.0160-412010.1016/j.envint.2022.107476info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:42:30Zoai:repositorio.insa.pt:10400.18/8297Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:42:58.961812Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030
title Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030
spellingShingle Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030
Zare Jeddi, Maryam
Human Biomonitoring
Environmental Genotoxicity
Chemicals Mixtures
Data Governance
Zero Pollution Ambition
One Substance-one Assessment
Circular Economy
European Exposure Science Strategy
Europe
Genotoxicidade Ambiental
title_short Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030
title_full Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030
title_fullStr Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030
title_full_unstemmed Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030
title_sort Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030
author Zare Jeddi, Maryam
author_facet Zare Jeddi, Maryam
Hopf, Nancy B.
Louro, Henriqueta
Viegas, Susana
Galea, Karen S.
Pasanen-Kase, Robert
Santonen, Tiina
Mustieles, Vicente
Fernandez, Mariana F.
Verhagen, Hans
Bopp, Stephanie K.
Antignac, Jean Philippe
David, Arthur
Mol, Hans
Barouki, Robert
Audouze, Karine
Duca, Radu-Corneliu
Fantke, Peter
Scheepers, Paul
Ghosh, Manosij
Van Nieuwenhuyse, An
Lobo Vicente, Joana
Trier, Xenia
Rambaud, Loïc
Fillol, Clémence
Denys, Sebastien
Conrad, André
Kolossa-Gehring, Marike
Paini, Alicia
Arnot, Jon
Schulze, Florian
Jones, Kate
Sepai, Ovnair
Ali, Imran
Brennan, Lorraine
Benfenati, Emilio
Cubadda, Francesco
Mantovani, Alberto
Bartonova, Alena
Connolly, Alison
Slobodnik, Jaroslav
Bruinen de Bruin, Yuri
van Klaveren, Jacob
Palmen, Nicole
Dirven, Hubert
Husøy, Trine
Thomsen, Cathrine
Virgolino, Ana
Röösli, Martin
Gant, Tim
von Goetz, Natalie
Bessems, Jos
author_role author
author2 Hopf, Nancy B.
Louro, Henriqueta
Viegas, Susana
Galea, Karen S.
Pasanen-Kase, Robert
Santonen, Tiina
Mustieles, Vicente
Fernandez, Mariana F.
Verhagen, Hans
Bopp, Stephanie K.
Antignac, Jean Philippe
David, Arthur
Mol, Hans
Barouki, Robert
Audouze, Karine
Duca, Radu-Corneliu
Fantke, Peter
Scheepers, Paul
Ghosh, Manosij
Van Nieuwenhuyse, An
Lobo Vicente, Joana
Trier, Xenia
Rambaud, Loïc
Fillol, Clémence
Denys, Sebastien
Conrad, André
Kolossa-Gehring, Marike
Paini, Alicia
Arnot, Jon
Schulze, Florian
Jones, Kate
Sepai, Ovnair
Ali, Imran
Brennan, Lorraine
Benfenati, Emilio
Cubadda, Francesco
Mantovani, Alberto
Bartonova, Alena
Connolly, Alison
Slobodnik, Jaroslav
Bruinen de Bruin, Yuri
van Klaveren, Jacob
Palmen, Nicole
Dirven, Hubert
Husøy, Trine
Thomsen, Cathrine
Virgolino, Ana
Röösli, Martin
Gant, Tim
von Goetz, Natalie
Bessems, Jos
author2_role author
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author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
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author
author
author
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author
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dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Zare Jeddi, Maryam
Hopf, Nancy B.
Louro, Henriqueta
Viegas, Susana
Galea, Karen S.
Pasanen-Kase, Robert
Santonen, Tiina
Mustieles, Vicente
Fernandez, Mariana F.
Verhagen, Hans
Bopp, Stephanie K.
Antignac, Jean Philippe
David, Arthur
Mol, Hans
Barouki, Robert
Audouze, Karine
Duca, Radu-Corneliu
Fantke, Peter
Scheepers, Paul
Ghosh, Manosij
Van Nieuwenhuyse, An
Lobo Vicente, Joana
Trier, Xenia
Rambaud, Loïc
Fillol, Clémence
Denys, Sebastien
Conrad, André
Kolossa-Gehring, Marike
Paini, Alicia
Arnot, Jon
Schulze, Florian
Jones, Kate
Sepai, Ovnair
Ali, Imran
Brennan, Lorraine
Benfenati, Emilio
Cubadda, Francesco
Mantovani, Alberto
Bartonova, Alena
Connolly, Alison
Slobodnik, Jaroslav
Bruinen de Bruin, Yuri
van Klaveren, Jacob
Palmen, Nicole
Dirven, Hubert
Husøy, Trine
Thomsen, Cathrine
Virgolino, Ana
Röösli, Martin
Gant, Tim
von Goetz, Natalie
Bessems, Jos
dc.subject.por.fl_str_mv Human Biomonitoring
Environmental Genotoxicity
Chemicals Mixtures
Data Governance
Zero Pollution Ambition
One Substance-one Assessment
Circular Economy
European Exposure Science Strategy
Europe
Genotoxicidade Ambiental
topic Human Biomonitoring
Environmental Genotoxicity
Chemicals Mixtures
Data Governance
Zero Pollution Ambition
One Substance-one Assessment
Circular Economy
European Exposure Science Strategy
Europe
Genotoxicidade Ambiental
description Human biomonitoring (HBM) is a crucial approach for exposure assessment, as emphasised in the European Commission’s Chemicals Strategy for Sustainability (CSS). HBM can help to improve chemical policies in five major key areas: (1) assessing internal and aggregate exposure in different target populations; 2) assessing exposure to chemicals across life stages; (3) assessing combined exposure to multiple chemicals (mixtures); (4) bridging regulatory silos on aggregate exposure; and (5) enhancing the effectiveness of risk management measures. In this strategy paper we propose a vision and a strategy for the use of HBM in chemical regulations and public health policy in Europe and beyond. We outline six strategic objectives and a roadmap to further strengthen HBM approaches and increase their implementation in the regulatory risk assessment of chemicals to enhance our understanding of exposure and health impacts, enabling timely and targeted policy interventions and risk management. These strategic objectives are: 1) further development of sampling strategies and sample preparation; 2) further development of chemical-analytical HBM methods; 3) improving harmonisation throughout the HBM research life cycle; 4) further development of quality control / quality assurance throughout the HBM research life cycle; 5) obtain sustained funding and reinforcement by legislation; and 6) extend target-specific communication with scientists, policymakers, citizens and other stakeholders. HBM approaches are essential in risk assessment to address scientific, regulatory and societal challenges. HBM requires full and strong support from the scientific and regulatory domain to reach its full potential in public and occupational health assessment and in regulatory decision-making.
publishDate 2022
dc.date.none.fl_str_mv 2022-11-02T14:40:03Z
2022-08-28
2022-08-28T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/8297
url http://hdl.handle.net/10400.18/8297
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Environ Int. 2022 Aug 28;168:107476. doi: 10.1016/j.envint.2022.107476. Online ahead of print.
0160-4120
10.1016/j.envint.2022.107476
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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