Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.18/8297 |
Resumo: | Human biomonitoring (HBM) is a crucial approach for exposure assessment, as emphasised in the European Commission’s Chemicals Strategy for Sustainability (CSS). HBM can help to improve chemical policies in five major key areas: (1) assessing internal and aggregate exposure in different target populations; 2) assessing exposure to chemicals across life stages; (3) assessing combined exposure to multiple chemicals (mixtures); (4) bridging regulatory silos on aggregate exposure; and (5) enhancing the effectiveness of risk management measures. In this strategy paper we propose a vision and a strategy for the use of HBM in chemical regulations and public health policy in Europe and beyond. We outline six strategic objectives and a roadmap to further strengthen HBM approaches and increase their implementation in the regulatory risk assessment of chemicals to enhance our understanding of exposure and health impacts, enabling timely and targeted policy interventions and risk management. These strategic objectives are: 1) further development of sampling strategies and sample preparation; 2) further development of chemical-analytical HBM methods; 3) improving harmonisation throughout the HBM research life cycle; 4) further development of quality control / quality assurance throughout the HBM research life cycle; 5) obtain sustained funding and reinforcement by legislation; and 6) extend target-specific communication with scientists, policymakers, citizens and other stakeholders. HBM approaches are essential in risk assessment to address scientific, regulatory and societal challenges. HBM requires full and strong support from the scientific and regulatory domain to reach its full potential in public and occupational health assessment and in regulatory decision-making. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030Human BiomonitoringEnvironmental GenotoxicityChemicals MixturesData GovernanceZero Pollution AmbitionOne Substance-one AssessmentCircular EconomyEuropean Exposure Science StrategyEuropeGenotoxicidade AmbientalHuman biomonitoring (HBM) is a crucial approach for exposure assessment, as emphasised in the European Commission’s Chemicals Strategy for Sustainability (CSS). HBM can help to improve chemical policies in five major key areas: (1) assessing internal and aggregate exposure in different target populations; 2) assessing exposure to chemicals across life stages; (3) assessing combined exposure to multiple chemicals (mixtures); (4) bridging regulatory silos on aggregate exposure; and (5) enhancing the effectiveness of risk management measures. In this strategy paper we propose a vision and a strategy for the use of HBM in chemical regulations and public health policy in Europe and beyond. We outline six strategic objectives and a roadmap to further strengthen HBM approaches and increase their implementation in the regulatory risk assessment of chemicals to enhance our understanding of exposure and health impacts, enabling timely and targeted policy interventions and risk management. These strategic objectives are: 1) further development of sampling strategies and sample preparation; 2) further development of chemical-analytical HBM methods; 3) improving harmonisation throughout the HBM research life cycle; 4) further development of quality control / quality assurance throughout the HBM research life cycle; 5) obtain sustained funding and reinforcement by legislation; and 6) extend target-specific communication with scientists, policymakers, citizens and other stakeholders. HBM approaches are essential in risk assessment to address scientific, regulatory and societal challenges. HBM requires full and strong support from the scientific and regulatory domain to reach its full potential in public and occupational health assessment and in regulatory decision-making.ElsevierRepositório Científico do Instituto Nacional de SaúdeZare Jeddi, MaryamHopf, Nancy B.Louro, HenriquetaViegas, SusanaGalea, Karen S.Pasanen-Kase, RobertSantonen, TiinaMustieles, VicenteFernandez, Mariana F.Verhagen, HansBopp, Stephanie K.Antignac, Jean PhilippeDavid, ArthurMol, HansBarouki, RobertAudouze, KarineDuca, Radu-CorneliuFantke, PeterScheepers, PaulGhosh, ManosijVan Nieuwenhuyse, AnLobo Vicente, JoanaTrier, XeniaRambaud, LoïcFillol, ClémenceDenys, SebastienConrad, AndréKolossa-Gehring, MarikePaini, AliciaArnot, JonSchulze, FlorianJones, KateSepai, OvnairAli, ImranBrennan, LorraineBenfenati, EmilioCubadda, FrancescoMantovani, AlbertoBartonova, AlenaConnolly, AlisonSlobodnik, JaroslavBruinen de Bruin, Yurivan Klaveren, JacobPalmen, NicoleDirven, HubertHusøy, TrineThomsen, CathrineVirgolino, AnaRöösli, MartinGant, Timvon Goetz, NatalieBessems, Jos2022-11-02T14:40:03Z2022-08-282022-08-28T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/8297engEnviron Int. 2022 Aug 28;168:107476. doi: 10.1016/j.envint.2022.107476. Online ahead of print.0160-412010.1016/j.envint.2022.107476info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:42:30Zoai:repositorio.insa.pt:10400.18/8297Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:42:58.961812Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030 |
title |
Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030 |
spellingShingle |
Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030 Zare Jeddi, Maryam Human Biomonitoring Environmental Genotoxicity Chemicals Mixtures Data Governance Zero Pollution Ambition One Substance-one Assessment Circular Economy European Exposure Science Strategy Europe Genotoxicidade Ambiental |
title_short |
Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030 |
title_full |
Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030 |
title_fullStr |
Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030 |
title_full_unstemmed |
Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030 |
title_sort |
Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030 |
author |
Zare Jeddi, Maryam |
author_facet |
Zare Jeddi, Maryam Hopf, Nancy B. Louro, Henriqueta Viegas, Susana Galea, Karen S. Pasanen-Kase, Robert Santonen, Tiina Mustieles, Vicente Fernandez, Mariana F. Verhagen, Hans Bopp, Stephanie K. Antignac, Jean Philippe David, Arthur Mol, Hans Barouki, Robert Audouze, Karine Duca, Radu-Corneliu Fantke, Peter Scheepers, Paul Ghosh, Manosij Van Nieuwenhuyse, An Lobo Vicente, Joana Trier, Xenia Rambaud, Loïc Fillol, Clémence Denys, Sebastien Conrad, André Kolossa-Gehring, Marike Paini, Alicia Arnot, Jon Schulze, Florian Jones, Kate Sepai, Ovnair Ali, Imran Brennan, Lorraine Benfenati, Emilio Cubadda, Francesco Mantovani, Alberto Bartonova, Alena Connolly, Alison Slobodnik, Jaroslav Bruinen de Bruin, Yuri van Klaveren, Jacob Palmen, Nicole Dirven, Hubert Husøy, Trine Thomsen, Cathrine Virgolino, Ana Röösli, Martin Gant, Tim von Goetz, Natalie Bessems, Jos |
author_role |
author |
author2 |
Hopf, Nancy B. Louro, Henriqueta Viegas, Susana Galea, Karen S. Pasanen-Kase, Robert Santonen, Tiina Mustieles, Vicente Fernandez, Mariana F. Verhagen, Hans Bopp, Stephanie K. Antignac, Jean Philippe David, Arthur Mol, Hans Barouki, Robert Audouze, Karine Duca, Radu-Corneliu Fantke, Peter Scheepers, Paul Ghosh, Manosij Van Nieuwenhuyse, An Lobo Vicente, Joana Trier, Xenia Rambaud, Loïc Fillol, Clémence Denys, Sebastien Conrad, André Kolossa-Gehring, Marike Paini, Alicia Arnot, Jon Schulze, Florian Jones, Kate Sepai, Ovnair Ali, Imran Brennan, Lorraine Benfenati, Emilio Cubadda, Francesco Mantovani, Alberto Bartonova, Alena Connolly, Alison Slobodnik, Jaroslav Bruinen de Bruin, Yuri van Klaveren, Jacob Palmen, Nicole Dirven, Hubert Husøy, Trine Thomsen, Cathrine Virgolino, Ana Röösli, Martin Gant, Tim von Goetz, Natalie Bessems, Jos |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Nacional de Saúde |
dc.contributor.author.fl_str_mv |
Zare Jeddi, Maryam Hopf, Nancy B. Louro, Henriqueta Viegas, Susana Galea, Karen S. Pasanen-Kase, Robert Santonen, Tiina Mustieles, Vicente Fernandez, Mariana F. Verhagen, Hans Bopp, Stephanie K. Antignac, Jean Philippe David, Arthur Mol, Hans Barouki, Robert Audouze, Karine Duca, Radu-Corneliu Fantke, Peter Scheepers, Paul Ghosh, Manosij Van Nieuwenhuyse, An Lobo Vicente, Joana Trier, Xenia Rambaud, Loïc Fillol, Clémence Denys, Sebastien Conrad, André Kolossa-Gehring, Marike Paini, Alicia Arnot, Jon Schulze, Florian Jones, Kate Sepai, Ovnair Ali, Imran Brennan, Lorraine Benfenati, Emilio Cubadda, Francesco Mantovani, Alberto Bartonova, Alena Connolly, Alison Slobodnik, Jaroslav Bruinen de Bruin, Yuri van Klaveren, Jacob Palmen, Nicole Dirven, Hubert Husøy, Trine Thomsen, Cathrine Virgolino, Ana Röösli, Martin Gant, Tim von Goetz, Natalie Bessems, Jos |
dc.subject.por.fl_str_mv |
Human Biomonitoring Environmental Genotoxicity Chemicals Mixtures Data Governance Zero Pollution Ambition One Substance-one Assessment Circular Economy European Exposure Science Strategy Europe Genotoxicidade Ambiental |
topic |
Human Biomonitoring Environmental Genotoxicity Chemicals Mixtures Data Governance Zero Pollution Ambition One Substance-one Assessment Circular Economy European Exposure Science Strategy Europe Genotoxicidade Ambiental |
description |
Human biomonitoring (HBM) is a crucial approach for exposure assessment, as emphasised in the European Commission’s Chemicals Strategy for Sustainability (CSS). HBM can help to improve chemical policies in five major key areas: (1) assessing internal and aggregate exposure in different target populations; 2) assessing exposure to chemicals across life stages; (3) assessing combined exposure to multiple chemicals (mixtures); (4) bridging regulatory silos on aggregate exposure; and (5) enhancing the effectiveness of risk management measures. In this strategy paper we propose a vision and a strategy for the use of HBM in chemical regulations and public health policy in Europe and beyond. We outline six strategic objectives and a roadmap to further strengthen HBM approaches and increase their implementation in the regulatory risk assessment of chemicals to enhance our understanding of exposure and health impacts, enabling timely and targeted policy interventions and risk management. These strategic objectives are: 1) further development of sampling strategies and sample preparation; 2) further development of chemical-analytical HBM methods; 3) improving harmonisation throughout the HBM research life cycle; 4) further development of quality control / quality assurance throughout the HBM research life cycle; 5) obtain sustained funding and reinforcement by legislation; and 6) extend target-specific communication with scientists, policymakers, citizens and other stakeholders. HBM approaches are essential in risk assessment to address scientific, regulatory and societal challenges. HBM requires full and strong support from the scientific and regulatory domain to reach its full potential in public and occupational health assessment and in regulatory decision-making. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-11-02T14:40:03Z 2022-08-28 2022-08-28T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.18/8297 |
url |
http://hdl.handle.net/10400.18/8297 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Environ Int. 2022 Aug 28;168:107476. doi: 10.1016/j.envint.2022.107476. Online ahead of print. 0160-4120 10.1016/j.envint.2022.107476 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799132175843459072 |