NT-proBNP no diagnóstico de insuficiência cardíaca nos cuidados de saúde primários

Detalhes bibliográficos
Autor(a) principal: Fonseca, Cândida
Data de Publicação: 2022
Outros Autores: Bettencourt, Paulo, Brito, Dulce, Febra, Helena, Pereira, Álvaro, Genovez, Victória, Lopes, Nelson
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/135930
Resumo: Funding Information: This study was supported by Roche Diagnostics. The authors had full control of the content and made the final decision on all aspects of this article. Publisher Copyright: © 2021 Sociedade Portuguesa de Cardiologia
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spelling NT-proBNP no diagnóstico de insuficiência cardíaca nos cuidados de saúde primáriosNT-proBNP for heart failure diagnosis in Primary CareCosts or savings? A budget impact studyCustos ou ganhos? Estudo de impacto orçamentalBiomarkersChronic heart failureDiagnosisNatriuretic peptides NT-proBNPPrimary health careCardiology and Cardiovascular MedicineSDG 3 - Good Health and Well-beingFunding Information: This study was supported by Roche Diagnostics. The authors had full control of the content and made the final decision on all aspects of this article. Publisher Copyright: © 2021 Sociedade Portuguesa de CardiologiaIntroduction and objectives: Chronic heart failure (CHF) is a growing public health concern and diagnosis can be challenging, particularly in primary care. This study aims to estimate the budgetary impact of introducing N-terminal pro-B-type natriuretic peptide (NT-proBNP) for CHF diagnosis in a primary care setting from the perspective of the Portuguese health system. Methods: A budget impact analysis was conducted over one-year from the patients’ first presentation. The standard of care (SoC) was compared to NT-proBNP at the point-of-care (PoC) or laboratory (Lab). A decision tree model was used to estimate the downstream costs associated with each of the three pathways. Results: An estimated 81 012 patients were expected to present to primary care with new onset CHF symptoms. The use of NT-proBNP as a primary diagnostic tool is estimated to generate annualized savings of EUR 935 657 and EUR 2 982 443 in the Lab and PoC setting, respectively. Estimated cost savings were due to the need for fewer medical visits, hospitalizations and echocardiograms (ECHO). The Lab and PoC settings led to similar reductions in hospitalizations (14.4%) and ECHO (27%), but the reduction in medical visits was higher in the PoC setting (38% compared to 2.5%), resulting in higher savings compared to Lab. Conclusions: Using NT-proBNP for CHF diagnosis in primary care could result in considerable costs savings for the public health system in Portugal. This evidence might support health policy makers to reconsider the resource management and define a new strategy to mitigate the impact of CHF.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNFonseca, CândidaBettencourt, PauloBrito, DulceFebra, HelenaPereira, ÁlvaroGenovez, VictóriaLopes, Nelson2022-04-05T22:57:59Z2022-032022-03-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article11application/pdfhttp://hdl.handle.net/10362/135930por0870-2551PURE: 42980761https://doi.org/10.1016/j.repc.2021.03.009info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:14:14Zoai:run.unl.pt:10362/135930Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:48:33.477437Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv NT-proBNP no diagnóstico de insuficiência cardíaca nos cuidados de saúde primários
NT-proBNP for heart failure diagnosis in Primary CareCosts or savings? A budget impact study
Custos ou ganhos? Estudo de impacto orçamental
title NT-proBNP no diagnóstico de insuficiência cardíaca nos cuidados de saúde primários
spellingShingle NT-proBNP no diagnóstico de insuficiência cardíaca nos cuidados de saúde primários
Fonseca, Cândida
Biomarkers
Chronic heart failure
Diagnosis
Natriuretic peptides NT-proBNP
Primary health care
Cardiology and Cardiovascular Medicine
SDG 3 - Good Health and Well-being
title_short NT-proBNP no diagnóstico de insuficiência cardíaca nos cuidados de saúde primários
title_full NT-proBNP no diagnóstico de insuficiência cardíaca nos cuidados de saúde primários
title_fullStr NT-proBNP no diagnóstico de insuficiência cardíaca nos cuidados de saúde primários
title_full_unstemmed NT-proBNP no diagnóstico de insuficiência cardíaca nos cuidados de saúde primários
title_sort NT-proBNP no diagnóstico de insuficiência cardíaca nos cuidados de saúde primários
author Fonseca, Cândida
author_facet Fonseca, Cândida
Bettencourt, Paulo
Brito, Dulce
Febra, Helena
Pereira, Álvaro
Genovez, Victória
Lopes, Nelson
author_role author
author2 Bettencourt, Paulo
Brito, Dulce
Febra, Helena
Pereira, Álvaro
Genovez, Victória
Lopes, Nelson
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Fonseca, Cândida
Bettencourt, Paulo
Brito, Dulce
Febra, Helena
Pereira, Álvaro
Genovez, Victória
Lopes, Nelson
dc.subject.por.fl_str_mv Biomarkers
Chronic heart failure
Diagnosis
Natriuretic peptides NT-proBNP
Primary health care
Cardiology and Cardiovascular Medicine
SDG 3 - Good Health and Well-being
topic Biomarkers
Chronic heart failure
Diagnosis
Natriuretic peptides NT-proBNP
Primary health care
Cardiology and Cardiovascular Medicine
SDG 3 - Good Health and Well-being
description Funding Information: This study was supported by Roche Diagnostics. The authors had full control of the content and made the final decision on all aspects of this article. Publisher Copyright: © 2021 Sociedade Portuguesa de Cardiologia
publishDate 2022
dc.date.none.fl_str_mv 2022-04-05T22:57:59Z
2022-03
2022-03-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/135930
url http://hdl.handle.net/10362/135930
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 0870-2551
PURE: 42980761
https://doi.org/10.1016/j.repc.2021.03.009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 11
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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