Hepatitis C Virus Core Antigen Test: an HCV RNA screening alternative in end-stage renal disease and hemodialysis?

Detalhes bibliográficos
Autor(a) principal: Alves,Rita V
Data de Publicação: 2019
Outros Autores: Gonçalves,Hernâni, Gonçalves,Maria L, Lopes,Karina, Sofia,Flora, Lobos,Ana V
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692019000200003
Resumo: Introduction and Aim:Hepatitis C virus screening using anti-HCV antibody is recommended for end-stage renal disease and chronic hemodialysis patients. Since the anti-HCV antibody test is not able to differentiate a concurrent infection from a resolved past one, a more reliable and cost-effective screening test is needed. Materials and Methods: Prospective study of end-stage renal disease and chronic hemodialysis patients from a hospital unit who were screened by anti-HCV antibody and total ARCHITECT® HCV antigen assay. Results: Cohen's κ test was run to determine if there was agreement between HCV Ribonucleic Acid and HCV core antigen assays on 7 individuals with positive anti-HCV antibody. The two tests had a perfect measurement agreement. Conclusions: HCV core antigen testing could be used as a sensitive method for HCV infection screening in this group of patients based on its accuracy, simplicity and low expense
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spelling Hepatitis C Virus Core Antigen Test: an HCV RNA screening alternative in end-stage renal disease and hemodialysis?Anti-HCV antibodyDiagnosisHCV RNAInfectionIntroduction and Aim:Hepatitis C virus screening using anti-HCV antibody is recommended for end-stage renal disease and chronic hemodialysis patients. Since the anti-HCV antibody test is not able to differentiate a concurrent infection from a resolved past one, a more reliable and cost-effective screening test is needed. Materials and Methods: Prospective study of end-stage renal disease and chronic hemodialysis patients from a hospital unit who were screened by anti-HCV antibody and total ARCHITECT® HCV antigen assay. Results: Cohen's κ test was run to determine if there was agreement between HCV Ribonucleic Acid and HCV core antigen assays on 7 individuals with positive anti-HCV antibody. The two tests had a perfect measurement agreement. Conclusions: HCV core antigen testing could be used as a sensitive method for HCV infection screening in this group of patients based on its accuracy, simplicity and low expenseSociedade Portuguesa de Nefrologia2019-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692019000200003Portuguese Journal of Nephrology & Hypertension v.33 n.2 2019reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692019000200003Alves,Rita VGonçalves,HernâniGonçalves,Maria LLopes,KarinaSofia,FloraLobos,Ana Vinfo:eu-repo/semantics/openAccess2024-02-06T17:05:02Zoai:scielo:S0872-01692019000200003Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:19:02.162572Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Hepatitis C Virus Core Antigen Test: an HCV RNA screening alternative in end-stage renal disease and hemodialysis?
title Hepatitis C Virus Core Antigen Test: an HCV RNA screening alternative in end-stage renal disease and hemodialysis?
spellingShingle Hepatitis C Virus Core Antigen Test: an HCV RNA screening alternative in end-stage renal disease and hemodialysis?
Alves,Rita V
Anti-HCV antibody
Diagnosis
HCV RNA
Infection
title_short Hepatitis C Virus Core Antigen Test: an HCV RNA screening alternative in end-stage renal disease and hemodialysis?
title_full Hepatitis C Virus Core Antigen Test: an HCV RNA screening alternative in end-stage renal disease and hemodialysis?
title_fullStr Hepatitis C Virus Core Antigen Test: an HCV RNA screening alternative in end-stage renal disease and hemodialysis?
title_full_unstemmed Hepatitis C Virus Core Antigen Test: an HCV RNA screening alternative in end-stage renal disease and hemodialysis?
title_sort Hepatitis C Virus Core Antigen Test: an HCV RNA screening alternative in end-stage renal disease and hemodialysis?
author Alves,Rita V
author_facet Alves,Rita V
Gonçalves,Hernâni
Gonçalves,Maria L
Lopes,Karina
Sofia,Flora
Lobos,Ana V
author_role author
author2 Gonçalves,Hernâni
Gonçalves,Maria L
Lopes,Karina
Sofia,Flora
Lobos,Ana V
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Alves,Rita V
Gonçalves,Hernâni
Gonçalves,Maria L
Lopes,Karina
Sofia,Flora
Lobos,Ana V
dc.subject.por.fl_str_mv Anti-HCV antibody
Diagnosis
HCV RNA
Infection
topic Anti-HCV antibody
Diagnosis
HCV RNA
Infection
description Introduction and Aim:Hepatitis C virus screening using anti-HCV antibody is recommended for end-stage renal disease and chronic hemodialysis patients. Since the anti-HCV antibody test is not able to differentiate a concurrent infection from a resolved past one, a more reliable and cost-effective screening test is needed. Materials and Methods: Prospective study of end-stage renal disease and chronic hemodialysis patients from a hospital unit who were screened by anti-HCV antibody and total ARCHITECT® HCV antigen assay. Results: Cohen's κ test was run to determine if there was agreement between HCV Ribonucleic Acid and HCV core antigen assays on 7 individuals with positive anti-HCV antibody. The two tests had a perfect measurement agreement. Conclusions: HCV core antigen testing could be used as a sensitive method for HCV infection screening in this group of patients based on its accuracy, simplicity and low expense
publishDate 2019
dc.date.none.fl_str_mv 2019-06-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692019000200003
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692019000200003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692019000200003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Nefrologia
publisher.none.fl_str_mv Sociedade Portuguesa de Nefrologia
dc.source.none.fl_str_mv Portuguese Journal of Nephrology & Hypertension v.33 n.2 2019
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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