Task force for a rapid response to an outbreak of severe acute hepatitis of unknown aetiology in children in Portugal in 2022

Detalhes bibliográficos
Autor(a) principal: Grau-Pujol, Berta
Data de Publicação: 2023
Outros Autores: Vieira Martins, Joao, Goncalves, Isabel, Rodrigues, Fernanda, de Sousa, Rita, Oliveira, Dina, Bettencourt, Joana, Mendes, Diana, de Cunha, Ines Mateus, Pocinho, Sara, Firme, Ana, Dos Santos, Benvinda Estela, Santos, Andre Peralta, Albuquerque, Maria Joao, Pinto-Leite, Pedro, Marinho, Rui Tato, Vasconcelos, Paula
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/159680
Resumo: Funding Information: BGP is a fellow of the ECDC Fellowship Programme, supported financially by the ECDC. The views and opinions expressed herein do not state or reflect those of the ECDC. The ECDC is not responsible for the data and information collation and analysis and cannot be held liable for conclusions or opinions drawn. All the other authors have no competing interests. Publisher Copyright: © 2023 European Centre for Disease Prevention and Control (ECDC). All rights reserved.
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spelling Task force for a rapid response to an outbreak of severe acute hepatitis of unknown aetiology in children in Portugal in 2022EpidemiologyPublic Health, Environmental and Occupational HealthVirologySDG 3 - Good Health and Well-beingFunding Information: BGP is a fellow of the ECDC Fellowship Programme, supported financially by the ECDC. The views and opinions expressed herein do not state or reflect those of the ECDC. The ECDC is not responsible for the data and information collation and analysis and cannot be held liable for conclusions or opinions drawn. All the other authors have no competing interests. Publisher Copyright: © 2023 European Centre for Disease Prevention and Control (ECDC). All rights reserved.On 5 April 2022, the United Kingdom reported an increase of cases of severe acute hepatitis of unknown aetiology in children, several needing hospitalisation and some required liver transplant or died. Thereafter, 35 countries reported probable cases, almost half of them in Europe. Facing the alert, on 28 April, Portugal created a multidisciplinary Task Force (TF) for rapid detection of probable cases and response. The experts of the TF came from various disciplines: clinicians, laboratory experts, epidemiologists, public health experts and national and international communication. Moreover, Portugal adopted the European Centre for Disease Prevention and Control (ECDC) and the World Health Organization (WHO) case definition and recommendations. By 31 December 2022, 28 probable cases of severe acute hepatitis of unknown aetiology were reported: 16 male and 17 aged under 2 years. Of these cases, 23 were hospitalised but none required liver transplant or died. Adenovirus was detected from nine of 26 tested cases. No association was observed between adenovirus infection and hospital admission after adjusting for age, sex and region in a binomial regression model. The TF in Portugal may have contributed to increase awareness among clinicians, enabling early detection and prompt management of the outbreak.Escola Nacional de Saúde Pública (ENSP)Comprehensive Health Research Centre (CHRC) - Pólo ENSPCentro de Investigação em Saúde Pública (CISP/PHRC)RUNGrau-Pujol, BertaVieira Martins, JoaoGoncalves, IsabelRodrigues, Fernandade Sousa, RitaOliveira, DinaBettencourt, JoanaMendes, Dianade Cunha, Ines MateusPocinho, SaraFirme, AnaDos Santos, Benvinda EstelaSantos, Andre PeraltaAlbuquerque, Maria JoaoPinto-Leite, PedroMarinho, Rui TatoVasconcelos, Paula2023-11-07T22:09:25Z2023-09-212023-09-21T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/159680eng1025-496XPURE: 75592118https://doi.org/10.2807/1560-7917.ES.2023.28.38.2300171info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:42:07Zoai:run.unl.pt:10362/159680Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:57:39.220587Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Task force for a rapid response to an outbreak of severe acute hepatitis of unknown aetiology in children in Portugal in 2022
title Task force for a rapid response to an outbreak of severe acute hepatitis of unknown aetiology in children in Portugal in 2022
spellingShingle Task force for a rapid response to an outbreak of severe acute hepatitis of unknown aetiology in children in Portugal in 2022
Grau-Pujol, Berta
Epidemiology
Public Health, Environmental and Occupational Health
Virology
SDG 3 - Good Health and Well-being
title_short Task force for a rapid response to an outbreak of severe acute hepatitis of unknown aetiology in children in Portugal in 2022
title_full Task force for a rapid response to an outbreak of severe acute hepatitis of unknown aetiology in children in Portugal in 2022
title_fullStr Task force for a rapid response to an outbreak of severe acute hepatitis of unknown aetiology in children in Portugal in 2022
title_full_unstemmed Task force for a rapid response to an outbreak of severe acute hepatitis of unknown aetiology in children in Portugal in 2022
title_sort Task force for a rapid response to an outbreak of severe acute hepatitis of unknown aetiology in children in Portugal in 2022
author Grau-Pujol, Berta
author_facet Grau-Pujol, Berta
Vieira Martins, Joao
Goncalves, Isabel
Rodrigues, Fernanda
de Sousa, Rita
Oliveira, Dina
Bettencourt, Joana
Mendes, Diana
de Cunha, Ines Mateus
Pocinho, Sara
Firme, Ana
Dos Santos, Benvinda Estela
Santos, Andre Peralta
Albuquerque, Maria Joao
Pinto-Leite, Pedro
Marinho, Rui Tato
Vasconcelos, Paula
author_role author
author2 Vieira Martins, Joao
Goncalves, Isabel
Rodrigues, Fernanda
de Sousa, Rita
Oliveira, Dina
Bettencourt, Joana
Mendes, Diana
de Cunha, Ines Mateus
Pocinho, Sara
Firme, Ana
Dos Santos, Benvinda Estela
Santos, Andre Peralta
Albuquerque, Maria Joao
Pinto-Leite, Pedro
Marinho, Rui Tato
Vasconcelos, Paula
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Escola Nacional de Saúde Pública (ENSP)
Comprehensive Health Research Centre (CHRC) - Pólo ENSP
Centro de Investigação em Saúde Pública (CISP/PHRC)
RUN
dc.contributor.author.fl_str_mv Grau-Pujol, Berta
Vieira Martins, Joao
Goncalves, Isabel
Rodrigues, Fernanda
de Sousa, Rita
Oliveira, Dina
Bettencourt, Joana
Mendes, Diana
de Cunha, Ines Mateus
Pocinho, Sara
Firme, Ana
Dos Santos, Benvinda Estela
Santos, Andre Peralta
Albuquerque, Maria Joao
Pinto-Leite, Pedro
Marinho, Rui Tato
Vasconcelos, Paula
dc.subject.por.fl_str_mv Epidemiology
Public Health, Environmental and Occupational Health
Virology
SDG 3 - Good Health and Well-being
topic Epidemiology
Public Health, Environmental and Occupational Health
Virology
SDG 3 - Good Health and Well-being
description Funding Information: BGP is a fellow of the ECDC Fellowship Programme, supported financially by the ECDC. The views and opinions expressed herein do not state or reflect those of the ECDC. The ECDC is not responsible for the data and information collation and analysis and cannot be held liable for conclusions or opinions drawn. All the other authors have no competing interests. Publisher Copyright: © 2023 European Centre for Disease Prevention and Control (ECDC). All rights reserved.
publishDate 2023
dc.date.none.fl_str_mv 2023-11-07T22:09:25Z
2023-09-21
2023-09-21T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/159680
url http://hdl.handle.net/10362/159680
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1025-496X
PURE: 75592118
https://doi.org/10.2807/1560-7917.ES.2023.28.38.2300171
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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