Determinants of fatal outcome in patients admitted to intensive care units with influenza, European Union 2009–2017
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2019 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10400.18/6612 |
Resumo: | Free PMC article: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/32258201/ |
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Determinants of fatal outcome in patients admitted to intensive care units with influenza, European Union 2009–2017Influenza VirusIntensive Care UnitsUnderlying Medical ConditionsAgeEUInfecções RespiratóriasFree PMC article: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/32258201/Background: Morbidity, severity, and mortality associated with annual influenza epidemics are of public health concern. We analyzed surveillance data on hospitalized laboratory-confirmed influenza cases admitted to intensive care units to identify common determinants for fatal outcome and inform and target public health prevention strategies, including risk communication. Methods: We performed a descriptive analysis and used Poisson regression models with robust variance to estimate the association of age, sex, virus (sub)type, and underlying medical condition with fatal outcome using European Union data from 2009 to 2017. Results: Of 13 368 cases included in the basic dataset, 2806 (21%) were fatal. Age ≥40 years and infection with influenza A virus were associated with fatal outcome. Of 5886 cases with known underlying medical conditions and virus A subtype included in a more detailed analysis, 1349 (23%) were fatal. Influenza virus A(H1N1)pdm09 or A(H3N2) infection, age ≥60 years, cancer, human immunodeficiency virus infection and/or other immune deficiency, and heart, kidney, and liver disease were associated with fatal outcome; the risk of death was lower for patients with chronic lung disease and for pregnant women. Conclusions: This study re-emphasises the importance of preventing influenza in the elderly and tailoring strategies to risk groups with underlying medical conditions.Oxford University Press/ on behalf of Infectious Diseases Society of AmericaRepositório Científico do Instituto Nacional de SaúdePenttinen, PasiSnacken, RenéLyytikäinen, OutiIkonen, NiinaMelillo, TanyaMelillo, Jackie M.Staroňová, EditaMikas, JánPopow-Kraupp, TheresiaOrta Gomes, Carlos M.Guiomar, RaquelSlezák, PavelKynčl, JanMeijer, AdamVan Gageldonk-Lafeber, Arianne B.Domegan, LisaO’Donnell, JoanLupulescu, EmiliaPopovici, OdetteCarnahan, AnnasaraBrytting, MiaDelgado-Sanz, ConcepciónOliva Domínguez, Jesús A.Larrauri, AmparoHubert, BrunoBonmarin, IsabelleGomes Dias, JoanaAdlhoch, Cornelia2020-05-08T09:58:52Z2019-10-292019-10-29T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/6612engOpen Forum Infect Dis. 2019 Oct 29;6(11):ofz462. doi: 10.1093/ofid/ofz462. eCollection 2019 Nov.2328-895710.1093/ofid/ofz462info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:41:45Zoai:repositorio.insa.pt:10400.18/6612Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:41:41.851108Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Determinants of fatal outcome in patients admitted to intensive care units with influenza, European Union 2009–2017 |
| title |
Determinants of fatal outcome in patients admitted to intensive care units with influenza, European Union 2009–2017 |
| spellingShingle |
Determinants of fatal outcome in patients admitted to intensive care units with influenza, European Union 2009–2017 Penttinen, Pasi Influenza Virus Intensive Care Units Underlying Medical Conditions Age EU Infecções Respiratórias |
| title_short |
Determinants of fatal outcome in patients admitted to intensive care units with influenza, European Union 2009–2017 |
| title_full |
Determinants of fatal outcome in patients admitted to intensive care units with influenza, European Union 2009–2017 |
| title_fullStr |
Determinants of fatal outcome in patients admitted to intensive care units with influenza, European Union 2009–2017 |
| title_full_unstemmed |
Determinants of fatal outcome in patients admitted to intensive care units with influenza, European Union 2009–2017 |
| title_sort |
Determinants of fatal outcome in patients admitted to intensive care units with influenza, European Union 2009–2017 |
| author |
Penttinen, Pasi |
| author_facet |
Penttinen, Pasi Snacken, René Lyytikäinen, Outi Ikonen, Niina Melillo, Tanya Melillo, Jackie M. Staroňová, Edita Mikas, Ján Popow-Kraupp, Theresia Orta Gomes, Carlos M. Guiomar, Raquel Slezák, Pavel Kynčl, Jan Meijer, Adam Van Gageldonk-Lafeber, Arianne B. Domegan, Lisa O’Donnell, Joan Lupulescu, Emilia Popovici, Odette Carnahan, Annasara Brytting, Mia Delgado-Sanz, Concepción Oliva Domínguez, Jesús A. Larrauri, Amparo Hubert, Bruno Bonmarin, Isabelle Gomes Dias, Joana Adlhoch, Cornelia |
| author_role |
author |
| author2 |
Snacken, René Lyytikäinen, Outi Ikonen, Niina Melillo, Tanya Melillo, Jackie M. Staroňová, Edita Mikas, Ján Popow-Kraupp, Theresia Orta Gomes, Carlos M. Guiomar, Raquel Slezák, Pavel Kynčl, Jan Meijer, Adam Van Gageldonk-Lafeber, Arianne B. Domegan, Lisa O’Donnell, Joan Lupulescu, Emilia Popovici, Odette Carnahan, Annasara Brytting, Mia Delgado-Sanz, Concepción Oliva Domínguez, Jesús A. Larrauri, Amparo Hubert, Bruno Bonmarin, Isabelle Gomes Dias, Joana Adlhoch, Cornelia |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Nacional de Saúde |
| dc.contributor.author.fl_str_mv |
Penttinen, Pasi Snacken, René Lyytikäinen, Outi Ikonen, Niina Melillo, Tanya Melillo, Jackie M. Staroňová, Edita Mikas, Ján Popow-Kraupp, Theresia Orta Gomes, Carlos M. Guiomar, Raquel Slezák, Pavel Kynčl, Jan Meijer, Adam Van Gageldonk-Lafeber, Arianne B. Domegan, Lisa O’Donnell, Joan Lupulescu, Emilia Popovici, Odette Carnahan, Annasara Brytting, Mia Delgado-Sanz, Concepción Oliva Domínguez, Jesús A. Larrauri, Amparo Hubert, Bruno Bonmarin, Isabelle Gomes Dias, Joana Adlhoch, Cornelia |
| dc.subject.por.fl_str_mv |
Influenza Virus Intensive Care Units Underlying Medical Conditions Age EU Infecções Respiratórias |
| topic |
Influenza Virus Intensive Care Units Underlying Medical Conditions Age EU Infecções Respiratórias |
| description |
Free PMC article: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/32258201/ |
| publishDate |
2019 |
| dc.date.none.fl_str_mv |
2019-10-29 2019-10-29T00:00:00Z 2020-05-08T09:58:52Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.18/6612 |
| url |
http://hdl.handle.net/10400.18/6612 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Open Forum Infect Dis. 2019 Oct 29;6(11):ofz462. doi: 10.1093/ofid/ofz462. eCollection 2019 Nov. 2328-8957 10.1093/ofid/ofz462 |
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info:eu-repo/semantics/openAccess |
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openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Oxford University Press/ on behalf of Infectious Diseases Society of America |
| publisher.none.fl_str_mv |
Oxford University Press/ on behalf of Infectious Diseases Society of America |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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