Decreases in molecularity promote conversion when reactions are catalyzed by enzymes immobilized in slab-shaped beads

Detalhes bibliográficos
Autor(a) principal: Barros, R.M.
Data de Publicação: 1999
Outros Autores: Malcata, F. Xavier
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.14/6477
Resumo: Application of Fick's first law to substrate undergoing chemical reaction catalyzed by an enzyme immobilized in a porous slab-shaped bead leads to substrate concentration profiles that are flatter when the ratio of stoichiometric coefficients of product to reactant (x) is lower. Since the actual effectiveness factor decreases when x increases (at approximately the same rate irrespective of the value taken by the Michaelis-Menten parameter), then considerable overprediction of the conversion levels obtained within a given reaction timeframe will occur if the simplistic (and more easily modelled) situation of equimolar counterdiffusion is taken for modelling purposes when x>1.
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spelling Decreases in molecularity promote conversion when reactions are catalyzed by enzymes immobilized in slab-shaped beadsApplication of Fick's first law to substrate undergoing chemical reaction catalyzed by an enzyme immobilized in a porous slab-shaped bead leads to substrate concentration profiles that are flatter when the ratio of stoichiometric coefficients of product to reactant (x) is lower. Since the actual effectiveness factor decreases when x increases (at approximately the same rate irrespective of the value taken by the Michaelis-Menten parameter), then considerable overprediction of the conversion levels obtained within a given reaction timeframe will occur if the simplistic (and more easily modelled) situation of equimolar counterdiffusion is taken for modelling purposes when x>1.Springer VerlagVeritati - Repositório Institucional da Universidade Católica PortuguesaBarros, R.M.Malcata, F. Xavier2011-10-19T14:19:19Z19991999-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.14/6477engBARRIOS, R.M. ; MALCATA, F.X. - Decreases in molecularity promote conversion when reactions are catalyzed by enzymes immobilized in slab-shaped beads. Bioprocess and Biosystems Engineering. ISSN 1615-7605. Vol. 20, n.º 2 (1999), p. 101-10410.1007/s004490050566info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-12T17:10:45Zoai:repositorio.ucp.pt:10400.14/6477Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:05:57.230674Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Decreases in molecularity promote conversion when reactions are catalyzed by enzymes immobilized in slab-shaped beads
title Decreases in molecularity promote conversion when reactions are catalyzed by enzymes immobilized in slab-shaped beads
spellingShingle Decreases in molecularity promote conversion when reactions are catalyzed by enzymes immobilized in slab-shaped beads
Barros, R.M.
title_short Decreases in molecularity promote conversion when reactions are catalyzed by enzymes immobilized in slab-shaped beads
title_full Decreases in molecularity promote conversion when reactions are catalyzed by enzymes immobilized in slab-shaped beads
title_fullStr Decreases in molecularity promote conversion when reactions are catalyzed by enzymes immobilized in slab-shaped beads
title_full_unstemmed Decreases in molecularity promote conversion when reactions are catalyzed by enzymes immobilized in slab-shaped beads
title_sort Decreases in molecularity promote conversion when reactions are catalyzed by enzymes immobilized in slab-shaped beads
author Barros, R.M.
author_facet Barros, R.M.
Malcata, F. Xavier
author_role author
author2 Malcata, F. Xavier
author2_role author
dc.contributor.none.fl_str_mv Veritati - Repositório Institucional da Universidade Católica Portuguesa
dc.contributor.author.fl_str_mv Barros, R.M.
Malcata, F. Xavier
description Application of Fick's first law to substrate undergoing chemical reaction catalyzed by an enzyme immobilized in a porous slab-shaped bead leads to substrate concentration profiles that are flatter when the ratio of stoichiometric coefficients of product to reactant (x) is lower. Since the actual effectiveness factor decreases when x increases (at approximately the same rate irrespective of the value taken by the Michaelis-Menten parameter), then considerable overprediction of the conversion levels obtained within a given reaction timeframe will occur if the simplistic (and more easily modelled) situation of equimolar counterdiffusion is taken for modelling purposes when x>1.
publishDate 1999
dc.date.none.fl_str_mv 1999
1999-01-01T00:00:00Z
2011-10-19T14:19:19Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.14/6477
url http://hdl.handle.net/10400.14/6477
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv BARRIOS, R.M. ; MALCATA, F.X. - Decreases in molecularity promote conversion when reactions are catalyzed by enzymes immobilized in slab-shaped beads. Bioprocess and Biosystems Engineering. ISSN 1615-7605. Vol. 20, n.º 2 (1999), p. 101-104
10.1007/s004490050566
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer Verlag
publisher.none.fl_str_mv Springer Verlag
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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