Metal-catalyzed asymmetric aldol reactions

Detalhes bibliográficos
Autor(a) principal: Dias,Luiz C.
Data de Publicação: 2012
Outros Autores: Lucca Jr.,Emílio C. de, Ferreira,Marco A. B., Polo,Ellen C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532012001200003
Resumo: The aldol reaction is one of the most powerful and versatile methods for the construction of C-C bonds. Traditionally, this reaction was developed in a stoichiometric version; however, great efforts in the development of chiral catalysts for aldol reactions were performed in recent years. Thus, in this review article, the development of metal-mediated chiral catalysts in Mukaiyama-type aldol reaction, reductive aldol reaction and direct aldol reaction are discussed. Moreover, the application of these catalysts in the total synthesis of complex molecules is discussed.
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spelling Metal-catalyzed asymmetric aldol reactionsaldol reactionsasymmetric inductionchiral ligandstotal synthesisThe aldol reaction is one of the most powerful and versatile methods for the construction of C-C bonds. Traditionally, this reaction was developed in a stoichiometric version; however, great efforts in the development of chiral catalysts for aldol reactions were performed in recent years. Thus, in this review article, the development of metal-mediated chiral catalysts in Mukaiyama-type aldol reaction, reductive aldol reaction and direct aldol reaction are discussed. Moreover, the application of these catalysts in the total synthesis of complex molecules is discussed.Sociedade Brasileira de Química2012-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532012001200003Journal of the Brazilian Chemical Society v.23 n.12 2012reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532012001200003info:eu-repo/semantics/openAccessDias,Luiz C.Lucca Jr.,Emílio C. deFerreira,Marco A. B.Polo,Ellen C.eng2013-02-08T00:00:00Zoai:scielo:S0103-50532012001200003Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2013-02-08T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Metal-catalyzed asymmetric aldol reactions
title Metal-catalyzed asymmetric aldol reactions
spellingShingle Metal-catalyzed asymmetric aldol reactions
Dias,Luiz C.
aldol reactions
asymmetric induction
chiral ligands
total synthesis
title_short Metal-catalyzed asymmetric aldol reactions
title_full Metal-catalyzed asymmetric aldol reactions
title_fullStr Metal-catalyzed asymmetric aldol reactions
title_full_unstemmed Metal-catalyzed asymmetric aldol reactions
title_sort Metal-catalyzed asymmetric aldol reactions
author Dias,Luiz C.
author_facet Dias,Luiz C.
Lucca Jr.,Emílio C. de
Ferreira,Marco A. B.
Polo,Ellen C.
author_role author
author2 Lucca Jr.,Emílio C. de
Ferreira,Marco A. B.
Polo,Ellen C.
author2_role author
author
author
dc.contributor.author.fl_str_mv Dias,Luiz C.
Lucca Jr.,Emílio C. de
Ferreira,Marco A. B.
Polo,Ellen C.
dc.subject.por.fl_str_mv aldol reactions
asymmetric induction
chiral ligands
total synthesis
topic aldol reactions
asymmetric induction
chiral ligands
total synthesis
description The aldol reaction is one of the most powerful and versatile methods for the construction of C-C bonds. Traditionally, this reaction was developed in a stoichiometric version; however, great efforts in the development of chiral catalysts for aldol reactions were performed in recent years. Thus, in this review article, the development of metal-mediated chiral catalysts in Mukaiyama-type aldol reaction, reductive aldol reaction and direct aldol reaction are discussed. Moreover, the application of these catalysts in the total synthesis of complex molecules is discussed.
publishDate 2012
dc.date.none.fl_str_mv 2012-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532012001200003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532012001200003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532012001200003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.23 n.12 2012
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
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instname_str Sociedade Brasileira de Química (SBQ)
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institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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