Successful Treatment of Sthaphylococcus Peritonitis Using Oral Linezolid Without Catheter Removal in a Peritoneal Dialysis Patient

Detalhes bibliográficos
Autor(a) principal: Carvão,João
Data de Publicação: 2023
Outros Autores: Matias,Patrícia, Mirco,Ana, Branco,Patrícia
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692023000100028
Resumo: ABSTRACT Peritonitis is one of the main complications of peritoneal dialysis and accounts for considerable mortality and hospitalization. It is usually treated with intraperitoneal antibiotherapy, as it is the best way to achieve high concentrations at the site of infection. We report a case of an 86-year-old female patient with end-stage renal disease under continuous ambulatory peritoneal dialysis, who was admitted to our hospital with complaints of intense diffused abdominal pain. The effluent culture yielded Staphylococcus hominis only sensible to vancomycin and linezolid. She was diagnosed with peritonitis secondary to Staphylococcus hominis infection and treated with oral linezolid without cateter removal. Adequate linezolid peritoneal fluid concentration (between 3 and 20 μg/mL) was achieved and the antibiotic therapy was maintained for 21 days with clinical and analytical improvement. According to our knowledge, this was the first Staphylococcus peritonitis in a peritoneal dialysis patient, successfully treated with oral linezolid and has had linezolid levels monitored in the peritoneal dialysis effluent.
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spelling Successful Treatment of Sthaphylococcus Peritonitis Using Oral Linezolid Without Catheter Removal in a Peritoneal Dialysis PatientLinezolidPeritoneal DialysisPeritonitisRenal Insufficiency, ChronicABSTRACT Peritonitis is one of the main complications of peritoneal dialysis and accounts for considerable mortality and hospitalization. It is usually treated with intraperitoneal antibiotherapy, as it is the best way to achieve high concentrations at the site of infection. We report a case of an 86-year-old female patient with end-stage renal disease under continuous ambulatory peritoneal dialysis, who was admitted to our hospital with complaints of intense diffused abdominal pain. The effluent culture yielded Staphylococcus hominis only sensible to vancomycin and linezolid. She was diagnosed with peritonitis secondary to Staphylococcus hominis infection and treated with oral linezolid without cateter removal. Adequate linezolid peritoneal fluid concentration (between 3 and 20 μg/mL) was achieved and the antibiotic therapy was maintained for 21 days with clinical and analytical improvement. According to our knowledge, this was the first Staphylococcus peritonitis in a peritoneal dialysis patient, successfully treated with oral linezolid and has had linezolid levels monitored in the peritoneal dialysis effluent.Sociedade Portuguesa de Nefrologia2023-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692023000100028Portuguese Journal of Nephrology & Hypertension v.37 n.1 2023reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692023000100028Carvão,JoãoMatias,PatríciaMirco,AnaBranco,Patríciainfo:eu-repo/semantics/openAccess2024-02-06T17:05:16Zoai:scielo:S0872-01692023000100028Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:19:09.303948Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Successful Treatment of Sthaphylococcus Peritonitis Using Oral Linezolid Without Catheter Removal in a Peritoneal Dialysis Patient
title Successful Treatment of Sthaphylococcus Peritonitis Using Oral Linezolid Without Catheter Removal in a Peritoneal Dialysis Patient
spellingShingle Successful Treatment of Sthaphylococcus Peritonitis Using Oral Linezolid Without Catheter Removal in a Peritoneal Dialysis Patient
Carvão,João
Linezolid
Peritoneal Dialysis
Peritonitis
Renal Insufficiency, Chronic
title_short Successful Treatment of Sthaphylococcus Peritonitis Using Oral Linezolid Without Catheter Removal in a Peritoneal Dialysis Patient
title_full Successful Treatment of Sthaphylococcus Peritonitis Using Oral Linezolid Without Catheter Removal in a Peritoneal Dialysis Patient
title_fullStr Successful Treatment of Sthaphylococcus Peritonitis Using Oral Linezolid Without Catheter Removal in a Peritoneal Dialysis Patient
title_full_unstemmed Successful Treatment of Sthaphylococcus Peritonitis Using Oral Linezolid Without Catheter Removal in a Peritoneal Dialysis Patient
title_sort Successful Treatment of Sthaphylococcus Peritonitis Using Oral Linezolid Without Catheter Removal in a Peritoneal Dialysis Patient
author Carvão,João
author_facet Carvão,João
Matias,Patrícia
Mirco,Ana
Branco,Patrícia
author_role author
author2 Matias,Patrícia
Mirco,Ana
Branco,Patrícia
author2_role author
author
author
dc.contributor.author.fl_str_mv Carvão,João
Matias,Patrícia
Mirco,Ana
Branco,Patrícia
dc.subject.por.fl_str_mv Linezolid
Peritoneal Dialysis
Peritonitis
Renal Insufficiency, Chronic
topic Linezolid
Peritoneal Dialysis
Peritonitis
Renal Insufficiency, Chronic
description ABSTRACT Peritonitis is one of the main complications of peritoneal dialysis and accounts for considerable mortality and hospitalization. It is usually treated with intraperitoneal antibiotherapy, as it is the best way to achieve high concentrations at the site of infection. We report a case of an 86-year-old female patient with end-stage renal disease under continuous ambulatory peritoneal dialysis, who was admitted to our hospital with complaints of intense diffused abdominal pain. The effluent culture yielded Staphylococcus hominis only sensible to vancomycin and linezolid. She was diagnosed with peritonitis secondary to Staphylococcus hominis infection and treated with oral linezolid without cateter removal. Adequate linezolid peritoneal fluid concentration (between 3 and 20 μg/mL) was achieved and the antibiotic therapy was maintained for 21 days with clinical and analytical improvement. According to our knowledge, this was the first Staphylococcus peritonitis in a peritoneal dialysis patient, successfully treated with oral linezolid and has had linezolid levels monitored in the peritoneal dialysis effluent.
publishDate 2023
dc.date.none.fl_str_mv 2023-03-01
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dc.language.iso.fl_str_mv eng
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Nefrologia
publisher.none.fl_str_mv Sociedade Portuguesa de Nefrologia
dc.source.none.fl_str_mv Portuguese Journal of Nephrology & Hypertension v.37 n.1 2023
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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