Lung cancer
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/104616 |
Resumo: | BACKGROUND/AIM: This study characterized lung cancer (LC) in Portugal, to capture sex differences, regional variation, and spatial distribution. PATIENTS AND METHODS: Variables: age, sex, vital status, region of residence, degree of urbanization, histologic types and stage at diagnosis. Spatial analyses conducted to identify high (HIC) and low incidence (LIC) clusters. RESULTS: In total, 11,642 cases were diagnosed (76.6% male, 23.4% female), with a similar mean age at diagnosis. There were 23,6% locally advanced and 58.4% metastatic disease cases, with 13.4% alive five years after diagnosis. Non-small-cell LC accounted for 77.3% of which 40.8% was adenocarcinoma and 22.7% was squamous cell carcinoma. Standardized incident rate (IR) was 37.5/105, 65.2/105 in males, and 15.7/105 in females, with four HIC (urban) clusters and four LIC (non-urban). CONCLUSION: This study highlighted the sex differences in incidence, mortality, histology, and geographic distribution of LC in Portugal. Considering the advanced stages and the poor overall survival, understanding sex and geographic differences is important for public health interventions. |
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Lung cancera nationwide study to characterize sex differences, incidence, and spatial patterns in PortugalincidenceLung cancerPortugalsex differencesspatial cluster analysisBiochemistry, Genetics and Molecular Biology(all)PharmacologySDG 3 - Good Health and Well-beingSDG 11 - Sustainable Cities and CommunitiesBACKGROUND/AIM: This study characterized lung cancer (LC) in Portugal, to capture sex differences, regional variation, and spatial distribution. PATIENTS AND METHODS: Variables: age, sex, vital status, region of residence, degree of urbanization, histologic types and stage at diagnosis. Spatial analyses conducted to identify high (HIC) and low incidence (LIC) clusters. RESULTS: In total, 11,642 cases were diagnosed (76.6% male, 23.4% female), with a similar mean age at diagnosis. There were 23,6% locally advanced and 58.4% metastatic disease cases, with 13.4% alive five years after diagnosis. Non-small-cell LC accounted for 77.3% of which 40.8% was adenocarcinoma and 22.7% was squamous cell carcinoma. Standardized incident rate (IR) was 37.5/105, 65.2/105 in males, and 15.7/105 in females, with four HIC (urban) clusters and four LIC (non-urban). CONCLUSION: This study highlighted the sex differences in incidence, mortality, histology, and geographic distribution of LC in Portugal. Considering the advanced stages and the poor overall survival, understanding sex and geographic differences is important for public health interventions.Escola Nacional de Saúde Pública (ENSP)Centro de Investigação em Saúde Pública (CISP/PHRC)RUNGuerreiro, TeresaAntunes, LuisBastos, JoanaMayer, AlexandraForjaz, GoncaloAraujo, AntÓnioNunes, Carla2020-09-23T22:19:41Z2020-09-012020-09-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article9application/pdfhttp://hdl.handle.net/10362/104616eng1791-7549PURE: 19960238https://doi.org/10.21873/invivo.12092info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:50:08Zoai:run.unl.pt:10362/104616Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:40:17.498509Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Lung cancer a nationwide study to characterize sex differences, incidence, and spatial patterns in Portugal |
title |
Lung cancer |
spellingShingle |
Lung cancer Guerreiro, Teresa incidence Lung cancer Portugal sex differences spatial cluster analysis Biochemistry, Genetics and Molecular Biology(all) Pharmacology SDG 3 - Good Health and Well-being SDG 11 - Sustainable Cities and Communities |
title_short |
Lung cancer |
title_full |
Lung cancer |
title_fullStr |
Lung cancer |
title_full_unstemmed |
Lung cancer |
title_sort |
Lung cancer |
author |
Guerreiro, Teresa |
author_facet |
Guerreiro, Teresa Antunes, Luis Bastos, Joana Mayer, Alexandra Forjaz, Goncalo Araujo, AntÓnio Nunes, Carla |
author_role |
author |
author2 |
Antunes, Luis Bastos, Joana Mayer, Alexandra Forjaz, Goncalo Araujo, AntÓnio Nunes, Carla |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Escola Nacional de Saúde Pública (ENSP) Centro de Investigação em Saúde Pública (CISP/PHRC) RUN |
dc.contributor.author.fl_str_mv |
Guerreiro, Teresa Antunes, Luis Bastos, Joana Mayer, Alexandra Forjaz, Goncalo Araujo, AntÓnio Nunes, Carla |
dc.subject.por.fl_str_mv |
incidence Lung cancer Portugal sex differences spatial cluster analysis Biochemistry, Genetics and Molecular Biology(all) Pharmacology SDG 3 - Good Health and Well-being SDG 11 - Sustainable Cities and Communities |
topic |
incidence Lung cancer Portugal sex differences spatial cluster analysis Biochemistry, Genetics and Molecular Biology(all) Pharmacology SDG 3 - Good Health and Well-being SDG 11 - Sustainable Cities and Communities |
description |
BACKGROUND/AIM: This study characterized lung cancer (LC) in Portugal, to capture sex differences, regional variation, and spatial distribution. PATIENTS AND METHODS: Variables: age, sex, vital status, region of residence, degree of urbanization, histologic types and stage at diagnosis. Spatial analyses conducted to identify high (HIC) and low incidence (LIC) clusters. RESULTS: In total, 11,642 cases were diagnosed (76.6% male, 23.4% female), with a similar mean age at diagnosis. There were 23,6% locally advanced and 58.4% metastatic disease cases, with 13.4% alive five years after diagnosis. Non-small-cell LC accounted for 77.3% of which 40.8% was adenocarcinoma and 22.7% was squamous cell carcinoma. Standardized incident rate (IR) was 37.5/105, 65.2/105 in males, and 15.7/105 in females, with four HIC (urban) clusters and four LIC (non-urban). CONCLUSION: This study highlighted the sex differences in incidence, mortality, histology, and geographic distribution of LC in Portugal. Considering the advanced stages and the poor overall survival, understanding sex and geographic differences is important for public health interventions. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-09-23T22:19:41Z 2020-09-01 2020-09-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/104616 |
url |
http://hdl.handle.net/10362/104616 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1791-7549 PURE: 19960238 https://doi.org/10.21873/invivo.12092 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
9 application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799138018602254336 |