Comparative context analysis of codon pairs on an ORFeome scale
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10773/27689 |
Resumo: | Codon context is an important feature of gene primary structure that modulates mRNA decoding accuracy. We have developed an analytical software package and a graphical interface for comparative codon context analysis of all the open reading frames in a genome (the ORFeome). Using the complete ORFeome sequences of Saccharomyces cerevisiae, Schizosaccharomyces pombe, Candida albicans and Escherichia coli, we show that this methodology permits large-scale codon context comparisons and provides new insight on the rules that govern the evolution of codon-pair context. |
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Comparative context analysis of codon pairs on an ORFeome scaleCodon context is an important feature of gene primary structure that modulates mRNA decoding accuracy. We have developed an analytical software package and a graphical interface for comparative codon context analysis of all the open reading frames in a genome (the ORFeome). Using the complete ORFeome sequences of Saccharomyces cerevisiae, Schizosaccharomyces pombe, Candida albicans and Escherichia coli, we show that this methodology permits large-scale codon context comparisons and provides new insight on the rules that govern the evolution of codon-pair context.BMC2020-02-27T11:15:48Z2005-01-01T00:00:00Z2005info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10773/27689eng1474-760X10.1186/gb-2005-6-3-r28Moura, GabrielaPinheiro, MiguelSilva, RaquelMiranda, IsabelAfreixo, VeraDias, GasparFreitas, AdelaideOliveira, José L.Santos, Manuel A. S.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-22T11:53:36Zoai:ria.ua.pt:10773/27689Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:00:23.432160Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Comparative context analysis of codon pairs on an ORFeome scale |
title |
Comparative context analysis of codon pairs on an ORFeome scale |
spellingShingle |
Comparative context analysis of codon pairs on an ORFeome scale Moura, Gabriela |
title_short |
Comparative context analysis of codon pairs on an ORFeome scale |
title_full |
Comparative context analysis of codon pairs on an ORFeome scale |
title_fullStr |
Comparative context analysis of codon pairs on an ORFeome scale |
title_full_unstemmed |
Comparative context analysis of codon pairs on an ORFeome scale |
title_sort |
Comparative context analysis of codon pairs on an ORFeome scale |
author |
Moura, Gabriela |
author_facet |
Moura, Gabriela Pinheiro, Miguel Silva, Raquel Miranda, Isabel Afreixo, Vera Dias, Gaspar Freitas, Adelaide Oliveira, José L. Santos, Manuel A. S. |
author_role |
author |
author2 |
Pinheiro, Miguel Silva, Raquel Miranda, Isabel Afreixo, Vera Dias, Gaspar Freitas, Adelaide Oliveira, José L. Santos, Manuel A. S. |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Moura, Gabriela Pinheiro, Miguel Silva, Raquel Miranda, Isabel Afreixo, Vera Dias, Gaspar Freitas, Adelaide Oliveira, José L. Santos, Manuel A. S. |
description |
Codon context is an important feature of gene primary structure that modulates mRNA decoding accuracy. We have developed an analytical software package and a graphical interface for comparative codon context analysis of all the open reading frames in a genome (the ORFeome). Using the complete ORFeome sequences of Saccharomyces cerevisiae, Schizosaccharomyces pombe, Candida albicans and Escherichia coli, we show that this methodology permits large-scale codon context comparisons and provides new insight on the rules that govern the evolution of codon-pair context. |
publishDate |
2005 |
dc.date.none.fl_str_mv |
2005-01-01T00:00:00Z 2005 2020-02-27T11:15:48Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10773/27689 |
url |
http://hdl.handle.net/10773/27689 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1474-760X 10.1186/gb-2005-6-3-r28 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
BMC |
publisher.none.fl_str_mv |
BMC |
dc.source.none.fl_str_mv |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799137659480702976 |