Comparative context analysis of codon pairs on an ORFeome scale

Detalhes bibliográficos
Autor(a) principal: Moura, Gabriela
Data de Publicação: 2005
Outros Autores: Pinheiro, Miguel, Silva, Raquel, Miranda, Isabel, Afreixo, Vera, Dias, Gaspar, Freitas, Adelaide, Oliveira, José L., Santos, Manuel A. S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10773/27689
Resumo: Codon context is an important feature of gene primary structure that modulates mRNA decoding accuracy. We have developed an analytical software package and a graphical interface for comparative codon context analysis of all the open reading frames in a genome (the ORFeome). Using the complete ORFeome sequences of Saccharomyces cerevisiae, Schizosaccharomyces pombe, Candida albicans and Escherichia coli, we show that this methodology permits large-scale codon context comparisons and provides new insight on the rules that govern the evolution of codon-pair context.
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spelling Comparative context analysis of codon pairs on an ORFeome scaleCodon context is an important feature of gene primary structure that modulates mRNA decoding accuracy. We have developed an analytical software package and a graphical interface for comparative codon context analysis of all the open reading frames in a genome (the ORFeome). Using the complete ORFeome sequences of Saccharomyces cerevisiae, Schizosaccharomyces pombe, Candida albicans and Escherichia coli, we show that this methodology permits large-scale codon context comparisons and provides new insight on the rules that govern the evolution of codon-pair context.BMC2020-02-27T11:15:48Z2005-01-01T00:00:00Z2005info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10773/27689eng1474-760X10.1186/gb-2005-6-3-r28Moura, GabrielaPinheiro, MiguelSilva, RaquelMiranda, IsabelAfreixo, VeraDias, GasparFreitas, AdelaideOliveira, José L.Santos, Manuel A. S.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-22T11:53:36Zoai:ria.ua.pt:10773/27689Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:00:23.432160Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Comparative context analysis of codon pairs on an ORFeome scale
title Comparative context analysis of codon pairs on an ORFeome scale
spellingShingle Comparative context analysis of codon pairs on an ORFeome scale
Moura, Gabriela
title_short Comparative context analysis of codon pairs on an ORFeome scale
title_full Comparative context analysis of codon pairs on an ORFeome scale
title_fullStr Comparative context analysis of codon pairs on an ORFeome scale
title_full_unstemmed Comparative context analysis of codon pairs on an ORFeome scale
title_sort Comparative context analysis of codon pairs on an ORFeome scale
author Moura, Gabriela
author_facet Moura, Gabriela
Pinheiro, Miguel
Silva, Raquel
Miranda, Isabel
Afreixo, Vera
Dias, Gaspar
Freitas, Adelaide
Oliveira, José L.
Santos, Manuel A. S.
author_role author
author2 Pinheiro, Miguel
Silva, Raquel
Miranda, Isabel
Afreixo, Vera
Dias, Gaspar
Freitas, Adelaide
Oliveira, José L.
Santos, Manuel A. S.
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Moura, Gabriela
Pinheiro, Miguel
Silva, Raquel
Miranda, Isabel
Afreixo, Vera
Dias, Gaspar
Freitas, Adelaide
Oliveira, José L.
Santos, Manuel A. S.
description Codon context is an important feature of gene primary structure that modulates mRNA decoding accuracy. We have developed an analytical software package and a graphical interface for comparative codon context analysis of all the open reading frames in a genome (the ORFeome). Using the complete ORFeome sequences of Saccharomyces cerevisiae, Schizosaccharomyces pombe, Candida albicans and Escherichia coli, we show that this methodology permits large-scale codon context comparisons and provides new insight on the rules that govern the evolution of codon-pair context.
publishDate 2005
dc.date.none.fl_str_mv 2005-01-01T00:00:00Z
2005
2020-02-27T11:15:48Z
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10773/27689
url http://hdl.handle.net/10773/27689
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1474-760X
10.1186/gb-2005-6-3-r28
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dc.publisher.none.fl_str_mv BMC
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