Nephrolithiasis is associated with an increased prevalence of cardiovascular disease

Detalhes bibliográficos
Autor(a) principal: Domingos, F
Data de Publicação: 2011
Outros Autores: Serra, MA
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.10/454
Resumo: Background: Nephrolithiasis has been associated with hypertension, obesity and diabetes Mellitus. The prevalence of adverse cardiovascular outcomes among kidney stone formers (KSF) is unknown. Methods: We examined the IV Portuguese National Health Survey for documenting possible associations between nephrolithiasis, cardiovascular diseases, diabetes and obesity in the Portuguese adult population. Results: We obtained 23,349 questionnaires from individuals with ≥ 15 year-old. The prevalence of kidney stone disease was 7.3%. The prevalence of hypertension was higher among KSF when compared with the general population (50.4% vs. 30.2%; p < 0,001). Age and obesity significantly increase the risk for nephrolithiasis. After adjusting for age and body mass index, KSF have higher prevalence of hypertension (odds-ratio: 1.841; 95% CI: 1.651 – 2.053), diabetes Mellitus (odds-ratio: 1.475; 95% CI: 1.283 – 1.696; p < 0.001), myocardial infarction (odds-ratio: 1.338; 95% CI: 1.003 – 1.786; p < 0.05), and stroke (odds-ratio: 1.330; 95% CI: 1.015 – 1.743; p < 0.05) as compared with non-stone formers. Conclusions: Kidney stone disease is associated with a higher prevalence of chronic diseases and adverse cardiovascular outcomes when compared with the general population.
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spelling Nephrolithiasis is associated with an increased prevalence of cardiovascular diseaseNefrolitíaseDoenças cardiovascularesObesidadeHipertensãoDiabetes mellitusNephrolithiasisCardiovascular diseasesHypertensionObesityBackground: Nephrolithiasis has been associated with hypertension, obesity and diabetes Mellitus. The prevalence of adverse cardiovascular outcomes among kidney stone formers (KSF) is unknown. Methods: We examined the IV Portuguese National Health Survey for documenting possible associations between nephrolithiasis, cardiovascular diseases, diabetes and obesity in the Portuguese adult population. Results: We obtained 23,349 questionnaires from individuals with ≥ 15 year-old. The prevalence of kidney stone disease was 7.3%. The prevalence of hypertension was higher among KSF when compared with the general population (50.4% vs. 30.2%; p < 0,001). Age and obesity significantly increase the risk for nephrolithiasis. After adjusting for age and body mass index, KSF have higher prevalence of hypertension (odds-ratio: 1.841; 95% CI: 1.651 – 2.053), diabetes Mellitus (odds-ratio: 1.475; 95% CI: 1.283 – 1.696; p < 0.001), myocardial infarction (odds-ratio: 1.338; 95% CI: 1.003 – 1.786; p < 0.05), and stroke (odds-ratio: 1.330; 95% CI: 1.015 – 1.743; p < 0.05) as compared with non-stone formers. Conclusions: Kidney stone disease is associated with a higher prevalence of chronic diseases and adverse cardiovascular outcomes when compared with the general population.Oxford University PressRepositório do Hospital Prof. Doutor Fernando FonsecaDomingos, FSerra, MA2011-10-11T14:27:12Z2011-01-01T00:00:00Z2011-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.10/454engNephrol Dial Transplant. 2011 Mar;26(3):864-81460-2385info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-20T15:51:22Zoai:repositorio.hff.min-saude.pt:10400.10/454Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:51:44.798204Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Nephrolithiasis is associated with an increased prevalence of cardiovascular disease
title Nephrolithiasis is associated with an increased prevalence of cardiovascular disease
spellingShingle Nephrolithiasis is associated with an increased prevalence of cardiovascular disease
Domingos, F
Nefrolitíase
Doenças cardiovasculares
Obesidade
Hipertensão
Diabetes mellitus
Nephrolithiasis
Cardiovascular diseases
Hypertension
Obesity
title_short Nephrolithiasis is associated with an increased prevalence of cardiovascular disease
title_full Nephrolithiasis is associated with an increased prevalence of cardiovascular disease
title_fullStr Nephrolithiasis is associated with an increased prevalence of cardiovascular disease
title_full_unstemmed Nephrolithiasis is associated with an increased prevalence of cardiovascular disease
title_sort Nephrolithiasis is associated with an increased prevalence of cardiovascular disease
author Domingos, F
author_facet Domingos, F
Serra, MA
author_role author
author2 Serra, MA
author2_role author
dc.contributor.none.fl_str_mv Repositório do Hospital Prof. Doutor Fernando Fonseca
dc.contributor.author.fl_str_mv Domingos, F
Serra, MA
dc.subject.por.fl_str_mv Nefrolitíase
Doenças cardiovasculares
Obesidade
Hipertensão
Diabetes mellitus
Nephrolithiasis
Cardiovascular diseases
Hypertension
Obesity
topic Nefrolitíase
Doenças cardiovasculares
Obesidade
Hipertensão
Diabetes mellitus
Nephrolithiasis
Cardiovascular diseases
Hypertension
Obesity
description Background: Nephrolithiasis has been associated with hypertension, obesity and diabetes Mellitus. The prevalence of adverse cardiovascular outcomes among kidney stone formers (KSF) is unknown. Methods: We examined the IV Portuguese National Health Survey for documenting possible associations between nephrolithiasis, cardiovascular diseases, diabetes and obesity in the Portuguese adult population. Results: We obtained 23,349 questionnaires from individuals with ≥ 15 year-old. The prevalence of kidney stone disease was 7.3%. The prevalence of hypertension was higher among KSF when compared with the general population (50.4% vs. 30.2%; p < 0,001). Age and obesity significantly increase the risk for nephrolithiasis. After adjusting for age and body mass index, KSF have higher prevalence of hypertension (odds-ratio: 1.841; 95% CI: 1.651 – 2.053), diabetes Mellitus (odds-ratio: 1.475; 95% CI: 1.283 – 1.696; p < 0.001), myocardial infarction (odds-ratio: 1.338; 95% CI: 1.003 – 1.786; p < 0.05), and stroke (odds-ratio: 1.330; 95% CI: 1.015 – 1.743; p < 0.05) as compared with non-stone formers. Conclusions: Kidney stone disease is associated with a higher prevalence of chronic diseases and adverse cardiovascular outcomes when compared with the general population.
publishDate 2011
dc.date.none.fl_str_mv 2011-10-11T14:27:12Z
2011-01-01T00:00:00Z
2011-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.10/454
url http://hdl.handle.net/10400.10/454
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Nephrol Dial Transplant. 2011 Mar;26(3):864-8
1460-2385
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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