The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/12455 |
Resumo: | The Euterpe oleracea Mart. (açaí) is a plant from the Amazon region, classified as "super fruit" because of its various functional properties. However, limited investigation has been performed on açaí by-products, such as seeds. Therefore, the aim of this work was to characterized the phenolic compounds of the aqueous extract of açaí seeds and further evaluate its bioactivity (antioxidant and cytotoxic activities. Only proanthocyanidins were detected, being a B-type (epi)catechin tetramer the most abundant; however, procyanidin trimmers were the most predominant form. Açaí seeds extract revealed a high antioxidant (EC50 ranging from 3.6 to 19.4 μg/mL) and cytotoxic activity, being more effective in the cervical carcinoma cell line (HeLa; GI50 = 18 μg/mL); it did not show toxicity for non-tumor cells. Açaí seeds are considered a waste and could have an added economic benefit, through the extraction of natural antioxidants, particularly proanthocyanidins, that could find applications in food and pharmaceutical industries. |
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The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compoundsEuterpe oleraceaPhenolic characterizationAntioxidant propertiesAntitumor activityThe Euterpe oleracea Mart. (açaí) is a plant from the Amazon region, classified as "super fruit" because of its various functional properties. However, limited investigation has been performed on açaí by-products, such as seeds. Therefore, the aim of this work was to characterized the phenolic compounds of the aqueous extract of açaí seeds and further evaluate its bioactivity (antioxidant and cytotoxic activities. Only proanthocyanidins were detected, being a B-type (epi)catechin tetramer the most abundant; however, procyanidin trimmers were the most predominant form. Açaí seeds extract revealed a high antioxidant (EC50 ranging from 3.6 to 19.4 μg/mL) and cytotoxic activity, being more effective in the cervical carcinoma cell line (HeLa; GI50 = 18 μg/mL); it did not show toxicity for non-tumor cells. Açaí seeds are considered a waste and could have an added economic benefit, through the extraction of natural antioxidants, particularly proanthocyanidins, that could find applications in food and pharmaceutical industries.The authors are grateful to Foundation for Science and Technology (FCT, Portugal) for financial support to the research centre CIMO (strategic project PEst-OE/AGR/UI0690/2011) and L. Barros researcher contract under “Programa Compromisso com Ciência - 2008”. The authors are also grateful to Jamil S. Oliveira by the initial discussions on the preparation of samples.Biblioteca Digital do IPBBarros, LillianCalhelha, Ricardo C.Queiroz, Maria João R.P.Santos-Buelga, CelestinoSantos, Elândia A.Regis, Wiliam C.B.Ferreira, Isabel C.F.R.2015-11-30T10:52:11Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttp://hdl.handle.net/10198/12455engBarros, Lillian; Calhelha, Ricardo C.; Queiroz, Maria João R.P.; Santos-Buelga, Celestino; Santos, Elândia A.; Regis, Wiliam C.B.; Ferreira, Isabel C.F.R. (2015). The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds. Industrial Crops and Products. ISSN 0926-6690. 76, p. 318–3220926-669010.1016/j.indcrop.2015.05.086info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-01-16T12:14:19ZPortal AgregadorONG |
dc.title.none.fl_str_mv |
The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds |
title |
The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds |
spellingShingle |
The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds Barros, Lillian Euterpe oleracea Phenolic characterization Antioxidant properties Antitumor activity |
title_short |
The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds |
title_full |
The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds |
title_fullStr |
The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds |
title_full_unstemmed |
The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds |
title_sort |
The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds |
author |
Barros, Lillian |
author_facet |
Barros, Lillian Calhelha, Ricardo C. Queiroz, Maria João R.P. Santos-Buelga, Celestino Santos, Elândia A. Regis, Wiliam C.B. Ferreira, Isabel C.F.R. |
author_role |
author |
author2 |
Calhelha, Ricardo C. Queiroz, Maria João R.P. Santos-Buelga, Celestino Santos, Elândia A. Regis, Wiliam C.B. Ferreira, Isabel C.F.R. |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Barros, Lillian Calhelha, Ricardo C. Queiroz, Maria João R.P. Santos-Buelga, Celestino Santos, Elândia A. Regis, Wiliam C.B. Ferreira, Isabel C.F.R. |
dc.subject.por.fl_str_mv |
Euterpe oleracea Phenolic characterization Antioxidant properties Antitumor activity |
topic |
Euterpe oleracea Phenolic characterization Antioxidant properties Antitumor activity |
description |
The Euterpe oleracea Mart. (açaí) is a plant from the Amazon region, classified as "super fruit" because of its various functional properties. However, limited investigation has been performed on açaí by-products, such as seeds. Therefore, the aim of this work was to characterized the phenolic compounds of the aqueous extract of açaí seeds and further evaluate its bioactivity (antioxidant and cytotoxic activities. Only proanthocyanidins were detected, being a B-type (epi)catechin tetramer the most abundant; however, procyanidin trimmers were the most predominant form. Açaí seeds extract revealed a high antioxidant (EC50 ranging from 3.6 to 19.4 μg/mL) and cytotoxic activity, being more effective in the cervical carcinoma cell line (HeLa; GI50 = 18 μg/mL); it did not show toxicity for non-tumor cells. Açaí seeds are considered a waste and could have an added economic benefit, through the extraction of natural antioxidants, particularly proanthocyanidins, that could find applications in food and pharmaceutical industries. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-11-30T10:52:11Z 2015 2015-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/12455 |
url |
http://hdl.handle.net/10198/12455 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Barros, Lillian; Calhelha, Ricardo C.; Queiroz, Maria João R.P.; Santos-Buelga, Celestino; Santos, Elândia A.; Regis, Wiliam C.B.; Ferreira, Isabel C.F.R. (2015). The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds. Industrial Crops and Products. ISSN 0926-6690. 76, p. 318–322 0926-6690 10.1016/j.indcrop.2015.05.086 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.source.none.fl_str_mv |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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