Towards a Greener Approach for Biomass Valorization
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2023 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10362/158339 |
Resumo: | Funding Information: This project has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No 101003396. The biological activity has been supported by research ID: 3105-12-21. Publisher Copyright: © 2023 by the authors. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Towards a Greener Approach for Biomass ValorizationIntegration of Supercritical Fluid and Deep Eutectic Solventsantibacterial activityantioxidant activitydeep eutectic solventLavandula stoechassupercritical COMicrobiologyBiochemistryPharmacology, Toxicology and Pharmaceutics(all)Microbiology (medical)Infectious DiseasesPharmacology (medical)SDG 3 - Good Health and Well-beingSDG 8 - Decent Work and Economic GrowthSDG 12 - Responsible Consumption and ProductionFunding Information: This project has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No 101003396. The biological activity has been supported by research ID: 3105-12-21. Publisher Copyright: © 2023 by the authors.A green and sustainable procedure for obtaining Lavandula stoechas extracts with antioxidant and antimicrobial properties was investigated. Green solvents, supercritical CO2, and natural deep eutectic solvents (NADES) together with ultrasound-assisted extraction were used for the sequential extraction of terpene and polyphenols fractions. After the CO2 extraction of the terpene fraction, the residue material was used in an extraction with different NADES (betaine-ethylene glycol (Bet:EG), betaine-glycerol (Bet:Gly), and glycerol-glucose (Gly:Glu)), intensified with an ultrasound-assisted method (at 30 and 60 °C). In the CO2 extract, the major group of components belonged to oxygenated monoterpenes, while the highest polyphenol content with the dominant rutin (438.93 ± 4.60 µg/mL) was determined in Bet:EG extracts (60 °C). Bet:EG extracts also exhibited the most potent antioxidant activity according to DPPH, ABTS, and FRAP assays. Moreover, Bet:EG extracts showed significant inhibitory activity against Gram-positive and Gram-negative bacteria, with minimum inhibitory activity of 0.781–3.125 and 1.563–6.250 mg·mL−1, respectively. By comparing the polyphenolic content and antioxidant and antimicrobial activities of Bet:EG extracts with extracts obtained with conventional solvents (water and ethanol), the superiority of NADES was determined. The established environmentally friendly procedure unifies the requirements of green and sustainable development and modern pharmacognosy because it combines the use of safe alternative solvents, the absence of solvent waste generation, more rational use of resources, and the attainment of safe and quality extracts.LAQV@REQUIMTERUNVladić, JelenaJakovljević Kovač, MartinaPavić, ValentinaJokić, StelaSimić, SinišaPaiva, AlexandreJerković, IgorDuarte, Ana Rita2023-09-26T22:22:16Z2023-062023-06-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article17application/pdfhttp://hdl.handle.net/10362/158339eng2079-6382PURE: 72485433https://doi.org/10.3390/antibiotics12061031info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-22T18:14:41Zoai:run.unl.pt:10362/158339Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-22T18:14:41Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Towards a Greener Approach for Biomass Valorization Integration of Supercritical Fluid and Deep Eutectic Solvents |
| title |
Towards a Greener Approach for Biomass Valorization |
| spellingShingle |
Towards a Greener Approach for Biomass Valorization Vladić, Jelena antibacterial activity antioxidant activity deep eutectic solvent Lavandula stoechas supercritical CO Microbiology Biochemistry Pharmacology, Toxicology and Pharmaceutics(all) Microbiology (medical) Infectious Diseases Pharmacology (medical) SDG 3 - Good Health and Well-being SDG 8 - Decent Work and Economic Growth SDG 12 - Responsible Consumption and Production |
| title_short |
Towards a Greener Approach for Biomass Valorization |
| title_full |
Towards a Greener Approach for Biomass Valorization |
| title_fullStr |
Towards a Greener Approach for Biomass Valorization |
| title_full_unstemmed |
Towards a Greener Approach for Biomass Valorization |
| title_sort |
Towards a Greener Approach for Biomass Valorization |
| author |
Vladić, Jelena |
| author_facet |
Vladić, Jelena Jakovljević Kovač, Martina Pavić, Valentina Jokić, Stela Simić, Siniša Paiva, Alexandre Jerković, Igor Duarte, Ana Rita |
| author_role |
author |
| author2 |
Jakovljević Kovač, Martina Pavić, Valentina Jokić, Stela Simić, Siniša Paiva, Alexandre Jerković, Igor Duarte, Ana Rita |
| author2_role |
author author author author author author author |
| dc.contributor.none.fl_str_mv |
LAQV@REQUIMTE RUN |
| dc.contributor.author.fl_str_mv |
Vladić, Jelena Jakovljević Kovač, Martina Pavić, Valentina Jokić, Stela Simić, Siniša Paiva, Alexandre Jerković, Igor Duarte, Ana Rita |
| dc.subject.por.fl_str_mv |
antibacterial activity antioxidant activity deep eutectic solvent Lavandula stoechas supercritical CO Microbiology Biochemistry Pharmacology, Toxicology and Pharmaceutics(all) Microbiology (medical) Infectious Diseases Pharmacology (medical) SDG 3 - Good Health and Well-being SDG 8 - Decent Work and Economic Growth SDG 12 - Responsible Consumption and Production |
| topic |
antibacterial activity antioxidant activity deep eutectic solvent Lavandula stoechas supercritical CO Microbiology Biochemistry Pharmacology, Toxicology and Pharmaceutics(all) Microbiology (medical) Infectious Diseases Pharmacology (medical) SDG 3 - Good Health and Well-being SDG 8 - Decent Work and Economic Growth SDG 12 - Responsible Consumption and Production |
| description |
Funding Information: This project has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No 101003396. The biological activity has been supported by research ID: 3105-12-21. Publisher Copyright: © 2023 by the authors. |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2023-09-26T22:22:16Z 2023-06 2023-06-01T00:00:00Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/158339 |
| url |
http://hdl.handle.net/10362/158339 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
2079-6382 PURE: 72485433 https://doi.org/10.3390/antibiotics12061031 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
17 application/pdf |
| dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
| instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
| instacron_str |
RCAAP |
| institution |
RCAAP |
| reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
| repository.mail.fl_str_mv |
mluisa.alvim@gmail.com |
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1817545958056001536 |