Snake venom cathelicidins as natural antimicrobial peptides

Detalhes bibliográficos
Autor(a) principal: de Barros, Elizângela
Data de Publicação: 2019
Outros Autores: Gonçalves, Regina M., Cardoso, Marlon H., Santos, Nuno C., Franco, Octávio L., Cândido, Elizabete S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/52341
Resumo: Copyright © 2019 de Barros, Gonçalves, Cardoso, Santos, Franco and Cândido. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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spelling Snake venom cathelicidins as natural antimicrobial peptidesAntimicrobial peptidesCathelicidinsHost-defense peptidesNatural peptidesSnake venomCopyright © 2019 de Barros, Gonçalves, Cardoso, Santos, Franco and Cândido. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.Bioactive small molecules isolated from animals, plants, fungi and bacteria, including natural antimicrobial peptides, have shown great therapeutic potential worldwide. Among these peptides, snake venom cathelicidins are being widely exploited, because the variation in the composition of the venom reflects a range of biological activities that may be of biotechnological interest. Cathelicidins are short, cationic, and amphipathic molecules. They play an important role in host defense against microbial infections. We are currently facing a strong limitation on pharmacological interventions for infection control, which has become increasingly complex due to the lack of effective therapeutic options. In this review, we will focus on natural snake venom cathelicidins as promising candidates for the development of new antibacterial agents to fight antibiotic-resistant bacteria. We will highlight their antibacterial and antibiofilm activities, mechanism of action, and modulation of the innate immune response.This work was supported by Conselho Nacional de Pesquisa (CNPq); Coordenação de Aperfeiçoamento Pessoal de Nível Superior (CAPES); Fundação de Apoio à Pesquisa do Distrito Federal (FAPDF) and Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul (FUNDECT), Brazil.FrontiersRepositório da Universidade de Lisboade Barros, ElizângelaGonçalves, Regina M.Cardoso, Marlon H.Santos, Nuno C.Franco, Octávio L.Cândido, Elizabete S.2022-04-13T15:55:17Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/52341engFront Pharmacol. 2019 Nov 29;10:141510.3389/fphar.2019.014151663-9812info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:57:29Zoai:repositorio.ul.pt:10451/52341Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:03:27.731166Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Snake venom cathelicidins as natural antimicrobial peptides
title Snake venom cathelicidins as natural antimicrobial peptides
spellingShingle Snake venom cathelicidins as natural antimicrobial peptides
de Barros, Elizângela
Antimicrobial peptides
Cathelicidins
Host-defense peptides
Natural peptides
Snake venom
title_short Snake venom cathelicidins as natural antimicrobial peptides
title_full Snake venom cathelicidins as natural antimicrobial peptides
title_fullStr Snake venom cathelicidins as natural antimicrobial peptides
title_full_unstemmed Snake venom cathelicidins as natural antimicrobial peptides
title_sort Snake venom cathelicidins as natural antimicrobial peptides
author de Barros, Elizângela
author_facet de Barros, Elizângela
Gonçalves, Regina M.
Cardoso, Marlon H.
Santos, Nuno C.
Franco, Octávio L.
Cândido, Elizabete S.
author_role author
author2 Gonçalves, Regina M.
Cardoso, Marlon H.
Santos, Nuno C.
Franco, Octávio L.
Cândido, Elizabete S.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv de Barros, Elizângela
Gonçalves, Regina M.
Cardoso, Marlon H.
Santos, Nuno C.
Franco, Octávio L.
Cândido, Elizabete S.
dc.subject.por.fl_str_mv Antimicrobial peptides
Cathelicidins
Host-defense peptides
Natural peptides
Snake venom
topic Antimicrobial peptides
Cathelicidins
Host-defense peptides
Natural peptides
Snake venom
description Copyright © 2019 de Barros, Gonçalves, Cardoso, Santos, Franco and Cândido. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-01-01T00:00:00Z
2022-04-13T15:55:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/52341
url http://hdl.handle.net/10451/52341
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Front Pharmacol. 2019 Nov 29;10:1415
10.3389/fphar.2019.01415
1663-9812
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Frontiers
publisher.none.fl_str_mv Frontiers
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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