Measles, Mumps, and Rubella vaccination in children with egg allergy
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.25753/BirthGrowthMJ.v31.i1.23897 |
Resumo: | Introduction: Egg allergy is one of the most common food allergies in childhood. Administration of the measles, mumps, and rubella (MMR) vaccine is recommended in pediatric age. Despite the presence of traces of egg protein in its composition, the literature recommends MMR vaccine administration regardless of the patient’s past egg allergy history, identifying cases in which the administration should occur in hospital setting. Purpose: To characterize the pediatric population referred to the Allergy and Clinical Immunology Department of Centro Hospitalar Universitário do Porto for MMR vaccine administration and investigate vaccination safety in children with egg allergy or sensitization. Methods: This was a retrospective observational study of clinical records of children with confirmed or suspected egg allergy referred to the Allergy and Clinical Immunology Department for administration of the MMR vaccine between January 1, 2013 and December 31, 2019. Results: Among 60 children studied, 90% presented symptoms upon egg intake, with cutaneous reactions being the most prevalent (67%) and four reported cases of anaphylaxis. Allergy to cow’s milk protein (55%), followed by allergy to other foods (45%) were the most frequent personal histories of allergic diseases. Asthma was identified in 10% of patients and was controlled in all cases. Among children referred for vaccination booster dose, one had had a reaction to the previous MMR vaccine dose. Three children developed late local skin reactions, and one had a late systemic reaction after vaccination. All children had negative oral food challenge. Conclusion: MMR vaccine administration is safe and recommended in pediatric age, regardless of egg allergy history. However, immunization should be performed in hospital setting in children with a history of anaphylaxis due to egg allergy, previous anaphylactic reaction to MMR vaccine or one of its constituents, uncontrolled asthma with documented egg allergy, and uncontrolled asthma with allergy to a previous MMR vaccine dose. |
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Measles, Mumps, and Rubella vaccination in children with egg allergyVacinação Anti-Sarampo, Parotidite e Rubéola na criança com alergia ao ovoOriginal ArticlesIntroduction: Egg allergy is one of the most common food allergies in childhood. Administration of the measles, mumps, and rubella (MMR) vaccine is recommended in pediatric age. Despite the presence of traces of egg protein in its composition, the literature recommends MMR vaccine administration regardless of the patient’s past egg allergy history, identifying cases in which the administration should occur in hospital setting. Purpose: To characterize the pediatric population referred to the Allergy and Clinical Immunology Department of Centro Hospitalar Universitário do Porto for MMR vaccine administration and investigate vaccination safety in children with egg allergy or sensitization. Methods: This was a retrospective observational study of clinical records of children with confirmed or suspected egg allergy referred to the Allergy and Clinical Immunology Department for administration of the MMR vaccine between January 1, 2013 and December 31, 2019. Results: Among 60 children studied, 90% presented symptoms upon egg intake, with cutaneous reactions being the most prevalent (67%) and four reported cases of anaphylaxis. Allergy to cow’s milk protein (55%), followed by allergy to other foods (45%) were the most frequent personal histories of allergic diseases. Asthma was identified in 10% of patients and was controlled in all cases. Among children referred for vaccination booster dose, one had had a reaction to the previous MMR vaccine dose. Three children developed late local skin reactions, and one had a late systemic reaction after vaccination. All children had negative oral food challenge. Conclusion: MMR vaccine administration is safe and recommended in pediatric age, regardless of egg allergy history. However, immunization should be performed in hospital setting in children with a history of anaphylaxis due to egg allergy, previous anaphylactic reaction to MMR vaccine or one of its constituents, uncontrolled asthma with documented egg allergy, and uncontrolled asthma with allergy to a previous MMR vaccine dose.Introdução: A alergia ao ovo representa uma das alergias alimentares mais frequentes na infância. A administração da vacina anti-sarampo, parotidite e rubéola (VASPR) é recomendada em idade pediátrica. Apesar da presença de vestígios de ovalbumina na composição da vacina, a literatura recomenda a sua administração independentemente da história de alergia, advertindo para os casos em que a mesma deve ocorrer em ambiente hospitalar. Objetivo: Caracterizar a população pediátrica referenciada para a consulta de Imunoalergologia do Centro Hospitalar Universitário do Porto para administração da VASPR, bem como a segurança da mesma em crianças com alergia ou sensibilização ao ovo. Métodos: Estudo observacional retrospetivo dos processos clínicos de crianças referenciadas para a consulta de Imunoalergologia para administração da VASPR com alergia suspeita ou confirmado a ovo entre 1 de janeiro de 2013 e 31 de dezembro de 2019. Resultados: Das 60 crianças estudadas, 90% apresentaram sintomas mediante ingestão de ovo, predominantemente cutâneos (67%) mas também anafilaxia em quatro casos. Alergia à proteína do leite de vaca (55%), seguida da alergia a outros alimentos (45%) foram os antecedentes pessoais de doença alérgica mais frequentes. Foi identificada asma em 10% dos casos, encontrando-se controlada em todos. Das crianças referenciadas para administração de reforço vacinal, uma tinha apresentado reação à dose prévia da VASPR. Três crianças desenvolveram reação cutânea local tardia e uma desenvolveu reação sistémica tardia após administração da VASPR. Todas tiveram prova de provocação oral negativa. Conclusão: A administração da VASPR é segura e a sua recomendação mantém-se mesmo em crianças com alergia ao ovo. Contudo, a inoculação deve ser realizada em ambiente hospitalar em crianças com reação anafilática ao ovo, reação anafilática a uma dose prévia da vacina ou seus componentes, asma não controlada e alergia ao ovo, ou asma não controlada e alergia a uma dose prévia da vacina.Centro Hospitalar Universitário do Porto2022-04-04T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25753/BirthGrowthMJ.v31.i1.23897eng2183-9417Cunha, LeonorAlmeida, DianaRodrigues dos Santos, FilipaFalcão, Helenainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-21T14:55:43Zoai:ojs.revistas.rcaap.pt:article/23897Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:56:33.356123Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Measles, Mumps, and Rubella vaccination in children with egg allergy Vacinação Anti-Sarampo, Parotidite e Rubéola na criança com alergia ao ovo |
title |
Measles, Mumps, and Rubella vaccination in children with egg allergy |
spellingShingle |
Measles, Mumps, and Rubella vaccination in children with egg allergy Cunha, Leonor Original Articles |
title_short |
Measles, Mumps, and Rubella vaccination in children with egg allergy |
title_full |
Measles, Mumps, and Rubella vaccination in children with egg allergy |
title_fullStr |
Measles, Mumps, and Rubella vaccination in children with egg allergy |
title_full_unstemmed |
Measles, Mumps, and Rubella vaccination in children with egg allergy |
title_sort |
Measles, Mumps, and Rubella vaccination in children with egg allergy |
author |
Cunha, Leonor |
author_facet |
Cunha, Leonor Almeida, Diana Rodrigues dos Santos, Filipa Falcão, Helena |
author_role |
author |
author2 |
Almeida, Diana Rodrigues dos Santos, Filipa Falcão, Helena |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Cunha, Leonor Almeida, Diana Rodrigues dos Santos, Filipa Falcão, Helena |
dc.subject.por.fl_str_mv |
Original Articles |
topic |
Original Articles |
description |
Introduction: Egg allergy is one of the most common food allergies in childhood. Administration of the measles, mumps, and rubella (MMR) vaccine is recommended in pediatric age. Despite the presence of traces of egg protein in its composition, the literature recommends MMR vaccine administration regardless of the patient’s past egg allergy history, identifying cases in which the administration should occur in hospital setting. Purpose: To characterize the pediatric population referred to the Allergy and Clinical Immunology Department of Centro Hospitalar Universitário do Porto for MMR vaccine administration and investigate vaccination safety in children with egg allergy or sensitization. Methods: This was a retrospective observational study of clinical records of children with confirmed or suspected egg allergy referred to the Allergy and Clinical Immunology Department for administration of the MMR vaccine between January 1, 2013 and December 31, 2019. Results: Among 60 children studied, 90% presented symptoms upon egg intake, with cutaneous reactions being the most prevalent (67%) and four reported cases of anaphylaxis. Allergy to cow’s milk protein (55%), followed by allergy to other foods (45%) were the most frequent personal histories of allergic diseases. Asthma was identified in 10% of patients and was controlled in all cases. Among children referred for vaccination booster dose, one had had a reaction to the previous MMR vaccine dose. Three children developed late local skin reactions, and one had a late systemic reaction after vaccination. All children had negative oral food challenge. Conclusion: MMR vaccine administration is safe and recommended in pediatric age, regardless of egg allergy history. However, immunization should be performed in hospital setting in children with a history of anaphylaxis due to egg allergy, previous anaphylactic reaction to MMR vaccine or one of its constituents, uncontrolled asthma with documented egg allergy, and uncontrolled asthma with allergy to a previous MMR vaccine dose. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-04-04T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.25753/BirthGrowthMJ.v31.i1.23897 |
url |
https://doi.org/10.25753/BirthGrowthMJ.v31.i1.23897 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2183-9417 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Centro Hospitalar Universitário do Porto |
publisher.none.fl_str_mv |
Centro Hospitalar Universitário do Porto |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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