Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/50827 |
Resumo: | In this work, the authors propose a new quick sol–gel procedure for bioglass nanoparticles production containing 10% mol of silver (AgBGs). These new AgBGs are characterized by Zeta potential analysis, scanning electron microscopy with X-ray microanalysis (SEM/EDS), X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and microbiological tests to confirm their bioactive and antibacterial properties. SEM shows that the average particle size is less than 200 nm and EDS confirms the successful incorporation of Ag2O in the bioglass matrix. XRD confirms the amorphous nature of the AgBGs and, after SBF immersion, reveals their bioactive behavior with the presence of crystalline phase of calcium silicate and phosphorus oxide, which are also detected by FTIR analysis. FTIR also confirms the formation of typical siloxane bonds resulting from the condensation of silicate glass. Lastly, it is found that the developed AgBGs has an antibacterial effect against two different types of bacteria, thus demonstrating their ability to reduce the bacterial infection within 16 h. |
id |
RCAP_1f6da62c0a3263a6dc92593ac2989211 |
---|---|
oai_identifier_str |
oai:repositorium.sdum.uminho.pt:1822/50827 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
|
spelling |
Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applicationsAntibacterial propertiesBiomineralizationSilicate glassSilver doped nanoparticlesScience & TechnologyIn this work, the authors propose a new quick sol–gel procedure for bioglass nanoparticles production containing 10% mol of silver (AgBGs). These new AgBGs are characterized by Zeta potential analysis, scanning electron microscopy with X-ray microanalysis (SEM/EDS), X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and microbiological tests to confirm their bioactive and antibacterial properties. SEM shows that the average particle size is less than 200 nm and EDS confirms the successful incorporation of Ag2O in the bioglass matrix. XRD confirms the amorphous nature of the AgBGs and, after SBF immersion, reveals their bioactive behavior with the presence of crystalline phase of calcium silicate and phosphorus oxide, which are also detected by FTIR analysis. FTIR also confirms the formation of typical siloxane bonds resulting from the condensation of silicate glass. Lastly, it is found that the developed AgBGs has an antibacterial effect against two different types of bacteria, thus demonstrating their ability to reduce the bacterial infection within 16 h.The authors want to acknowledge the financial support from the Portuguese Foundation for Science and Technology through the project BioSeaGlue with the reference EXPL/CTM-BIO/0646/2013, and also the European program FEDER/COMPETE for the financial support through project LA ICVS/3Bs-2014-2015.info:eu-repo/semantics/publishedVersionWileyUniversidade do MinhoVale, Ana CatarinaCarvalho, Ana LuísaBarbosa, Ana Margarida MartinsTorrado, EgídioMano, J. F.Alves, N. M.20182018-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/50827eng1438-16561527-264810.1002/adem.201700855http://onlinelibrary.wiley.com/doi/10.1002/adem.201700855/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:46:38ZPortal AgregadorONG |
dc.title.none.fl_str_mv |
Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
title |
Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
spellingShingle |
Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications Vale, Ana Catarina Antibacterial properties Biomineralization Silicate glass Silver doped nanoparticles Science & Technology |
title_short |
Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
title_full |
Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
title_fullStr |
Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
title_full_unstemmed |
Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
title_sort |
Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
author |
Vale, Ana Catarina |
author_facet |
Vale, Ana Catarina Carvalho, Ana Luísa Barbosa, Ana Margarida Martins Torrado, Egídio Mano, J. F. Alves, N. M. |
author_role |
author |
author2 |
Carvalho, Ana Luísa Barbosa, Ana Margarida Martins Torrado, Egídio Mano, J. F. Alves, N. M. |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Vale, Ana Catarina Carvalho, Ana Luísa Barbosa, Ana Margarida Martins Torrado, Egídio Mano, J. F. Alves, N. M. |
dc.subject.por.fl_str_mv |
Antibacterial properties Biomineralization Silicate glass Silver doped nanoparticles Science & Technology |
topic |
Antibacterial properties Biomineralization Silicate glass Silver doped nanoparticles Science & Technology |
description |
In this work, the authors propose a new quick sol–gel procedure for bioglass nanoparticles production containing 10% mol of silver (AgBGs). These new AgBGs are characterized by Zeta potential analysis, scanning electron microscopy with X-ray microanalysis (SEM/EDS), X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and microbiological tests to confirm their bioactive and antibacterial properties. SEM shows that the average particle size is less than 200 nm and EDS confirms the successful incorporation of Ag2O in the bioglass matrix. XRD confirms the amorphous nature of the AgBGs and, after SBF immersion, reveals their bioactive behavior with the presence of crystalline phase of calcium silicate and phosphorus oxide, which are also detected by FTIR analysis. FTIR also confirms the formation of typical siloxane bonds resulting from the condensation of silicate glass. Lastly, it is found that the developed AgBGs has an antibacterial effect against two different types of bacteria, thus demonstrating their ability to reduce the bacterial infection within 16 h. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018 2018-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/50827 |
url |
http://hdl.handle.net/1822/50827 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1438-1656 1527-2648 10.1002/adem.201700855 http://onlinelibrary.wiley.com/doi/10.1002/adem.201700855/pdf |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
|
repository.mail.fl_str_mv |
|
_version_ |
1777303840611106816 |