Meat intake and risk of gastric cancer in the Stomach cancer Pooling (StoP) project
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://hdl.handle.net/10216/143194 |
Resumo: | The consumption of processed meat has been associated with noncardia gastric cancer, but evidence regarding a possible role of red meat is more limited. Our study aims to quantify the association between meat consumption, namely white, red and processed meat, and the risk of gastric cancer, through individual participant data meta-analysis of studies participating in the “Stomach cancer Pooling (StoP) Project”. Data from 22 studies, including 11,443 cases and 28,029 controls, were used. Study-specific odds ratios (ORs) were pooled through a two-stage approach based on random-effects models. An exposure-response relationship was modeled, using one and two-order fractional polynomials, to evaluate the possible nonlinear association between meat intake and gastric cancer. An increased risk of gastric cancer was observed for the consumption of all types of meat (highest vs. lowest tertile), which was statistically significant for red (OR: 1.24; 95% CI: 1.00–1.53), processed (OR: 1.23; 95% CI: 1.06–1.43) and total meat (OR: 1.30; 95% CI: 1.09–1.55). Exposure-response analyses showed an increasing risk of gastric cancer with increasing consumption of both processed and red meat, with the highest OR being observed for an intake of 150 g/day of red meat (OR: 1.85; 95% CI: 1.56–2.20). This work provides robust evidence on the relation between the consumption of different types of meat and gastric cancer. Adherence to dietary recommendations to reduce meat consumption may contribute to a reduction in the burden of gastric cancer. |
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Meat intake and risk of gastric cancer in the Stomach cancer Pooling (StoP) projectdietmeatnutritionpooled analysisstomach neoplasmsThe consumption of processed meat has been associated with noncardia gastric cancer, but evidence regarding a possible role of red meat is more limited. Our study aims to quantify the association between meat consumption, namely white, red and processed meat, and the risk of gastric cancer, through individual participant data meta-analysis of studies participating in the “Stomach cancer Pooling (StoP) Project”. Data from 22 studies, including 11,443 cases and 28,029 controls, were used. Study-specific odds ratios (ORs) were pooled through a two-stage approach based on random-effects models. An exposure-response relationship was modeled, using one and two-order fractional polynomials, to evaluate the possible nonlinear association between meat intake and gastric cancer. An increased risk of gastric cancer was observed for the consumption of all types of meat (highest vs. lowest tertile), which was statistically significant for red (OR: 1.24; 95% CI: 1.00–1.53), processed (OR: 1.23; 95% CI: 1.06–1.43) and total meat (OR: 1.30; 95% CI: 1.09–1.55). Exposure-response analyses showed an increasing risk of gastric cancer with increasing consumption of both processed and red meat, with the highest OR being observed for an intake of 150 g/day of red meat (OR: 1.85; 95% CI: 1.56–2.20). This work provides robust evidence on the relation between the consumption of different types of meat and gastric cancer. Adherence to dietary recommendations to reduce meat consumption may contribute to a reduction in the burden of gastric cancer.Wiley20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10216/143194eng0020-71361097-021510.1002/ijc.32707Ferro, ARosato, VRota, MCosta, ARMorais, SPelucchi, CJohnson, KCHu, JPalli, DFerraroni, MZhang, ZFBonzi, RYu, GPPeleteiro, BLópez-Carrillo, LTsugane, SHamade GSHidaka, AZaridze, DMaximovitch, DVioque, JNavarrete-Munoz, EMAragonés, NMartín, VHernández-Ramírez, RUBertuccio, PWard, MHMalekzadeh, RPourfarzi, FMu, LLópez-Cervantes, MPersiani, RKurtz, RCLagiou, ALagiou, PBoffetta, PBoccia, SNegri, ECamargo, MCCurado MPLa Vecchia, CLunet, Ninfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T15:20:50Zoai:repositorio-aberto.up.pt:10216/143194Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:21:17.799572Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Meat intake and risk of gastric cancer in the Stomach cancer Pooling (StoP) project |
title |
Meat intake and risk of gastric cancer in the Stomach cancer Pooling (StoP) project |
spellingShingle |
Meat intake and risk of gastric cancer in the Stomach cancer Pooling (StoP) project Ferro, A diet meat nutrition pooled analysis stomach neoplasms |
title_short |
Meat intake and risk of gastric cancer in the Stomach cancer Pooling (StoP) project |
title_full |
Meat intake and risk of gastric cancer in the Stomach cancer Pooling (StoP) project |
title_fullStr |
Meat intake and risk of gastric cancer in the Stomach cancer Pooling (StoP) project |
title_full_unstemmed |
Meat intake and risk of gastric cancer in the Stomach cancer Pooling (StoP) project |
title_sort |
Meat intake and risk of gastric cancer in the Stomach cancer Pooling (StoP) project |
author |
Ferro, A |
author_facet |
Ferro, A Rosato, V Rota, M Costa, AR Morais, S Pelucchi, C Johnson, KC Hu, J Palli, D Ferraroni, M Zhang, ZF Bonzi, R Yu, GP Peleteiro, B López-Carrillo, L Tsugane, S Hamade GS Hidaka, A Zaridze, D Maximovitch, D Vioque, J Navarrete-Munoz, EM Aragonés, N Martín, V Hernández-Ramírez, RU Bertuccio, P Ward, MH Malekzadeh, R Pourfarzi, F Mu, L López-Cervantes, M Persiani, R Kurtz, RC Lagiou, A Lagiou, P Boffetta, P Boccia, S Negri, E Camargo, MC Curado MP La Vecchia, C Lunet, N |
author_role |
author |
author2 |
Rosato, V Rota, M Costa, AR Morais, S Pelucchi, C Johnson, KC Hu, J Palli, D Ferraroni, M Zhang, ZF Bonzi, R Yu, GP Peleteiro, B López-Carrillo, L Tsugane, S Hamade GS Hidaka, A Zaridze, D Maximovitch, D Vioque, J Navarrete-Munoz, EM Aragonés, N Martín, V Hernández-Ramírez, RU Bertuccio, P Ward, MH Malekzadeh, R Pourfarzi, F Mu, L López-Cervantes, M Persiani, R Kurtz, RC Lagiou, A Lagiou, P Boffetta, P Boccia, S Negri, E Camargo, MC Curado MP La Vecchia, C Lunet, N |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Ferro, A Rosato, V Rota, M Costa, AR Morais, S Pelucchi, C Johnson, KC Hu, J Palli, D Ferraroni, M Zhang, ZF Bonzi, R Yu, GP Peleteiro, B López-Carrillo, L Tsugane, S Hamade GS Hidaka, A Zaridze, D Maximovitch, D Vioque, J Navarrete-Munoz, EM Aragonés, N Martín, V Hernández-Ramírez, RU Bertuccio, P Ward, MH Malekzadeh, R Pourfarzi, F Mu, L López-Cervantes, M Persiani, R Kurtz, RC Lagiou, A Lagiou, P Boffetta, P Boccia, S Negri, E Camargo, MC Curado MP La Vecchia, C Lunet, N |
dc.subject.por.fl_str_mv |
diet meat nutrition pooled analysis stomach neoplasms |
topic |
diet meat nutrition pooled analysis stomach neoplasms |
description |
The consumption of processed meat has been associated with noncardia gastric cancer, but evidence regarding a possible role of red meat is more limited. Our study aims to quantify the association between meat consumption, namely white, red and processed meat, and the risk of gastric cancer, through individual participant data meta-analysis of studies participating in the “Stomach cancer Pooling (StoP) Project”. Data from 22 studies, including 11,443 cases and 28,029 controls, were used. Study-specific odds ratios (ORs) were pooled through a two-stage approach based on random-effects models. An exposure-response relationship was modeled, using one and two-order fractional polynomials, to evaluate the possible nonlinear association between meat intake and gastric cancer. An increased risk of gastric cancer was observed for the consumption of all types of meat (highest vs. lowest tertile), which was statistically significant for red (OR: 1.24; 95% CI: 1.00–1.53), processed (OR: 1.23; 95% CI: 1.06–1.43) and total meat (OR: 1.30; 95% CI: 1.09–1.55). Exposure-response analyses showed an increasing risk of gastric cancer with increasing consumption of both processed and red meat, with the highest OR being observed for an intake of 150 g/day of red meat (OR: 1.85; 95% CI: 1.56–2.20). This work provides robust evidence on the relation between the consumption of different types of meat and gastric cancer. Adherence to dietary recommendations to reduce meat consumption may contribute to a reduction in the burden of gastric cancer. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020 2020-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/10216/143194 |
url |
https://hdl.handle.net/10216/143194 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0020-7136 1097-0215 10.1002/ijc.32707 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799136129117585408 |