Fruits and vegetables intake and gastric cancer risk: A pooled analysis within the Stomach cancer Pooling Project
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://hdl.handle.net/10216/143193 |
Resumo: | A low intake of fruits and vegetables is a risk factor for gastric cancer, although there is uncertainty regarding the magnitude of the associations. In our study, the relationship between fruits and vegetables intake and gastric cancer was assessed, complementing a previous work on the association betweenconsumption of citrus fruits and gastric cancer. Data from 25 studies (8456 cases and 21 133 controls) with information on fruits and/or vegetables intake were used. A two-stage approach based on random-effects models was used to pool study-specific adjusted (sex, age and the main known risk factors for gastric cancer) odds ratios (ORs) and the corresponding 95% confidence intervals (CIs). Exposure-response relations, including linear and nonlinear associations, were modeled using one- and two-order fractional polynomials. Gastric cancer risk was lower for a higher intake of fruits (OR: 0.76, 95% CI: 0.64-0.90), noncitrus fruits (OR: 0.86, 95% CI: 0.73-1.02), vegetables (OR: 0.68, 95% CI: 0.56-0.84), and fruits and vegetables (OR: 0.61, 95% CI: 0.49-0.75); results were consistent across sociodemographic and lifestyles categories, as well as study characteristics. Exposure-response analyses showed an increasingly protective effect of portions/day of fruits (OR: 0.64, 95% CI: 0.57-0.73 for six portions), noncitrus fruits (OR: 0.71, 95% CI: 0.61-0.83 for six portions) and vegetables (OR: 0.51, 95% CI: 0.43-0.60 for 10 portions). A protective effect of all fruits, noncitrus fruits and vegetables was confirmed, supporting further dietary recommendations to decrease the burden of gastric cancer. |
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Fruits and vegetables intake and gastric cancer risk: A pooled analysis within the Stomach cancer Pooling Projectfruitsgastric cancernutritionpooled analysesvegetablesA low intake of fruits and vegetables is a risk factor for gastric cancer, although there is uncertainty regarding the magnitude of the associations. In our study, the relationship between fruits and vegetables intake and gastric cancer was assessed, complementing a previous work on the association betweenconsumption of citrus fruits and gastric cancer. Data from 25 studies (8456 cases and 21 133 controls) with information on fruits and/or vegetables intake were used. A two-stage approach based on random-effects models was used to pool study-specific adjusted (sex, age and the main known risk factors for gastric cancer) odds ratios (ORs) and the corresponding 95% confidence intervals (CIs). Exposure-response relations, including linear and nonlinear associations, were modeled using one- and two-order fractional polynomials. Gastric cancer risk was lower for a higher intake of fruits (OR: 0.76, 95% CI: 0.64-0.90), noncitrus fruits (OR: 0.86, 95% CI: 0.73-1.02), vegetables (OR: 0.68, 95% CI: 0.56-0.84), and fruits and vegetables (OR: 0.61, 95% CI: 0.49-0.75); results were consistent across sociodemographic and lifestyles categories, as well as study characteristics. Exposure-response analyses showed an increasingly protective effect of portions/day of fruits (OR: 0.64, 95% CI: 0.57-0.73 for six portions), noncitrus fruits (OR: 0.71, 95% CI: 0.61-0.83 for six portions) and vegetables (OR: 0.51, 95% CI: 0.43-0.60 for 10 portions). A protective effect of all fruits, noncitrus fruits and vegetables was confirmed, supporting further dietary recommendations to decrease the burden of gastric cancer.Wiley20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10216/143193eng0020-71361097-021410.1002/ijc.33134Ferro, ACosta, ARMorais, SBertuccio, PRota, MPelucchi, CHu, JJohnson, KCZhang, ZFPalli, DFerraroni, MYu, GPBonzi, RPeleteiro, BLópez-Carrillo, LTsugane, SHamade GSHidaka, AMalekzadeh, RZaridze, DMaximovich, DVioque, JNavarrete-Muñoz, EMAlguacil, JCastaño-Vinyals, GWolk, AHåkansson, NHernández-Ramírez, RUPakseresht, MWard, MHPourfarzi, FMu, LLópez-Cervantes, MPersiani, RKurtz, RCLagiou, ALagiou, PBoffetta, PBoccia, SNegri, ECamargo, MCCurado, MPLa, Vecchia, CLunet, Ninfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T13:49:14Zoai:repositorio-aberto.up.pt:10216/143193Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:48:31.896525Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Fruits and vegetables intake and gastric cancer risk: A pooled analysis within the Stomach cancer Pooling Project |
title |
Fruits and vegetables intake and gastric cancer risk: A pooled analysis within the Stomach cancer Pooling Project |
spellingShingle |
Fruits and vegetables intake and gastric cancer risk: A pooled analysis within the Stomach cancer Pooling Project Ferro, A fruits gastric cancer nutrition pooled analyses vegetables |
title_short |
Fruits and vegetables intake and gastric cancer risk: A pooled analysis within the Stomach cancer Pooling Project |
title_full |
Fruits and vegetables intake and gastric cancer risk: A pooled analysis within the Stomach cancer Pooling Project |
title_fullStr |
Fruits and vegetables intake and gastric cancer risk: A pooled analysis within the Stomach cancer Pooling Project |
title_full_unstemmed |
Fruits and vegetables intake and gastric cancer risk: A pooled analysis within the Stomach cancer Pooling Project |
title_sort |
Fruits and vegetables intake and gastric cancer risk: A pooled analysis within the Stomach cancer Pooling Project |
author |
Ferro, A |
author_facet |
Ferro, A Costa, AR Morais, S Bertuccio, P Rota, M Pelucchi, C Hu, J Johnson, KC Zhang, ZF Palli, D Ferraroni, M Yu, GP Bonzi, R Peleteiro, B López-Carrillo, L Tsugane, S Hamade GS Hidaka, A Malekzadeh, R Zaridze, D Maximovich, D Vioque, J Navarrete-Muñoz, EM Alguacil, J Castaño-Vinyals, G Wolk, A Håkansson, N Hernández-Ramírez, RU Pakseresht, M Ward, MH Pourfarzi, F Mu, L López-Cervantes, M Persiani, R Kurtz, RC Lagiou, A Lagiou, P Boffetta, P Boccia, S Negri, E Camargo, MC Curado, MP La, Vecchia, C Lunet, N |
author_role |
author |
author2 |
Costa, AR Morais, S Bertuccio, P Rota, M Pelucchi, C Hu, J Johnson, KC Zhang, ZF Palli, D Ferraroni, M Yu, GP Bonzi, R Peleteiro, B López-Carrillo, L Tsugane, S Hamade GS Hidaka, A Malekzadeh, R Zaridze, D Maximovich, D Vioque, J Navarrete-Muñoz, EM Alguacil, J Castaño-Vinyals, G Wolk, A Håkansson, N Hernández-Ramírez, RU Pakseresht, M Ward, MH Pourfarzi, F Mu, L López-Cervantes, M Persiani, R Kurtz, RC Lagiou, A Lagiou, P Boffetta, P Boccia, S Negri, E Camargo, MC Curado, MP La, Vecchia, C Lunet, N |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Ferro, A Costa, AR Morais, S Bertuccio, P Rota, M Pelucchi, C Hu, J Johnson, KC Zhang, ZF Palli, D Ferraroni, M Yu, GP Bonzi, R Peleteiro, B López-Carrillo, L Tsugane, S Hamade GS Hidaka, A Malekzadeh, R Zaridze, D Maximovich, D Vioque, J Navarrete-Muñoz, EM Alguacil, J Castaño-Vinyals, G Wolk, A Håkansson, N Hernández-Ramírez, RU Pakseresht, M Ward, MH Pourfarzi, F Mu, L López-Cervantes, M Persiani, R Kurtz, RC Lagiou, A Lagiou, P Boffetta, P Boccia, S Negri, E Camargo, MC Curado, MP La, Vecchia, C Lunet, N |
dc.subject.por.fl_str_mv |
fruits gastric cancer nutrition pooled analyses vegetables |
topic |
fruits gastric cancer nutrition pooled analyses vegetables |
description |
A low intake of fruits and vegetables is a risk factor for gastric cancer, although there is uncertainty regarding the magnitude of the associations. In our study, the relationship between fruits and vegetables intake and gastric cancer was assessed, complementing a previous work on the association betweenconsumption of citrus fruits and gastric cancer. Data from 25 studies (8456 cases and 21 133 controls) with information on fruits and/or vegetables intake were used. A two-stage approach based on random-effects models was used to pool study-specific adjusted (sex, age and the main known risk factors for gastric cancer) odds ratios (ORs) and the corresponding 95% confidence intervals (CIs). Exposure-response relations, including linear and nonlinear associations, were modeled using one- and two-order fractional polynomials. Gastric cancer risk was lower for a higher intake of fruits (OR: 0.76, 95% CI: 0.64-0.90), noncitrus fruits (OR: 0.86, 95% CI: 0.73-1.02), vegetables (OR: 0.68, 95% CI: 0.56-0.84), and fruits and vegetables (OR: 0.61, 95% CI: 0.49-0.75); results were consistent across sociodemographic and lifestyles categories, as well as study characteristics. Exposure-response analyses showed an increasingly protective effect of portions/day of fruits (OR: 0.64, 95% CI: 0.57-0.73 for six portions), noncitrus fruits (OR: 0.71, 95% CI: 0.61-0.83 for six portions) and vegetables (OR: 0.51, 95% CI: 0.43-0.60 for 10 portions). A protective effect of all fruits, noncitrus fruits and vegetables was confirmed, supporting further dietary recommendations to decrease the burden of gastric cancer. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020 2020-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/10216/143193 |
url |
https://hdl.handle.net/10216/143193 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0020-7136 1097-0214 10.1002/ijc.33134 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799135804082094080 |