White matter lesions by magnetic resonance: an assessment between DWI and T2 FLAIR techniques
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.25758/set.594 |
Resumo: | Objectives – To determine the sensitivity and specificity of diffusion-weighted (DWI) and Fluid-Attenuated Inversion Recovery (T2 FLAIR) in the evaluation of white matter lesions and to verify what is his extended complement in order to create a set of best practices in the MRI routine of the brain. Methodology – Was carried out a quantitative study with retrospective analysis. From the database, were selected 30 patients, 20 with and 10 without the disease. We obtained a sample of 60 images, including 30-weighted images of T2 FLAIR and 30 of DWI. Using the program Viewdex®, the set of images was observed by three observers. The images were assessed according to seven criteria: visibility, detection, consistency, location, size, margins of the lesion, and diagnostic capability. We used the calculation of sensitivity and specificity by ROC curves, as well as statistical analysis, namely, T-test, Kappa index, and Pearson’s correlation coefficient between the variables under study. Results – The sensitivity and specificity obtained for the weighted T2 FLAIR were higher (0,915 and 0,038 respectively) than the weighting DWI (0.08 and 0.100 respectively). There were no significant population variances. We obtained a high linear correlation between variables with an r value located between 0.8 and 0.99. There was considerable variability among observers. Conclusions – Although the values of sensitivity and specificity for DWI have been lower than expected, we suggest that this sequence should be included in the routine protocol of the brain to help the differential diagnosis with other pathologies. |
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White matter lesions by magnetic resonance: an assessment between DWI and T2 FLAIR techniquesLesões da substância branca por ressonância magnética: uma avaliação entre as ponderações DWI e T2 FLAIRDWIT2 FLAIRRessonância magnéticaLesões da substância brancaDiffusionT2 FLAIRMRIWhite matter diseaseObjectives – To determine the sensitivity and specificity of diffusion-weighted (DWI) and Fluid-Attenuated Inversion Recovery (T2 FLAIR) in the evaluation of white matter lesions and to verify what is his extended complement in order to create a set of best practices in the MRI routine of the brain. Methodology – Was carried out a quantitative study with retrospective analysis. From the database, were selected 30 patients, 20 with and 10 without the disease. We obtained a sample of 60 images, including 30-weighted images of T2 FLAIR and 30 of DWI. Using the program Viewdex®, the set of images was observed by three observers. The images were assessed according to seven criteria: visibility, detection, consistency, location, size, margins of the lesion, and diagnostic capability. We used the calculation of sensitivity and specificity by ROC curves, as well as statistical analysis, namely, T-test, Kappa index, and Pearson’s correlation coefficient between the variables under study. Results – The sensitivity and specificity obtained for the weighted T2 FLAIR were higher (0,915 and 0,038 respectively) than the weighting DWI (0.08 and 0.100 respectively). There were no significant population variances. We obtained a high linear correlation between variables with an r value located between 0.8 and 0.99. There was considerable variability among observers. Conclusions – Although the values of sensitivity and specificity for DWI have been lower than expected, we suggest that this sequence should be included in the routine protocol of the brain to help the differential diagnosis with other pathologies.Objetivos – Determinar a sensibilidade e especificidade das ponderações Difusão (DWI) e T2 Fluid-Attenuated Inversion Recovery (FLAIR) na avaliação de lesões da substância branca (SB) e verificar em que medida se complementam, por forma a criar um conjunto de boas práticas na RM cranioencefálica de rotina. Metodologia – Recorrendo-se a uma metodologia quantitativa, efetuou-se uma análise retrospetiva da qual foram selecionados 30 pacientes, 10 sem patologia e 20 com patologia (2 com EM, 7 com Leucoencefalopatia, 6 com doença microangiopática e 5 com patologia da substância branca indefinida). Obteve-se uma amostra de 60 imagens, nomeadamente: 30 imagens ponderadas em DWI e 30 em T2 FLAIR. Recorrendo ao programa Viewdex®, três observadores avaliaram um conjunto de imagens segundo sete critérios: visibilidade, deteção, homogeneidade, localização, margens e dimensões da lesão e capacidade de diagnóstico. Com os resultados obtidos recorreu-se ao cálculo de sensibilidade e especificidade pelas Curvas ROC, bem como à análise estatística, nomeadamente, Teste-T, Índice de Concordância Kappa e coeficiente de correlação de Pearson entre as variáveis em estudo. Resultados – Os resultados de sensibilidade e de especificidade obtidos para a ponderação T2 FLAIR foram superiores (0,915 e 0,038, respetivamente) aos da ponderação DWI (0,08 e 0,100, respetivamente). Não se verificaram variâncias populacionais significativas. Obteve-se uma elevada correlação linear entre as variáveis com um valor r situado entre 0,8 e 0,99. Verificou-se também uma variabilidade considerável entre os observadores. Conclusões – Dados os baixos valores de sensibilidade e especificidade obtidos para a DWI, sugere-se que esta deva ser incluída no protocolo de rotina de crânio como auxiliar no diagnóstico diferencial com outras patologias.Escola Superior de Tecnologia da Saúde de Lisboa (Instituto Politécnico de Lisboa)2013-05-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.25758/set.594oai:journals.ipl.pt:article/666Saúde e Tecnologia; No. 09 (2013): Maio 2013; 16-23Saúde & Tecnologia; N.º 09 (2013): Maio 2013; 16-231646-9704reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://journals.ipl.pt/stecnologia/article/view/666https://doi.org/10.25758/set.594https://journals.ipl.pt/stecnologia/article/view/666/559Direitos de Autor (c) 2022 Saúde & Tecnologiainfo:eu-repo/semantics/openAccessCampos, CarlaSilva, RaquelRibeiro, Maria MargaridaLança, lu2022-12-20T10:59:14Zoai:journals.ipl.pt:article/666Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:21:28.439142Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
White matter lesions by magnetic resonance: an assessment between DWI and T2 FLAIR techniques Lesões da substância branca por ressonância magnética: uma avaliação entre as ponderações DWI e T2 FLAIR |
title |
White matter lesions by magnetic resonance: an assessment between DWI and T2 FLAIR techniques |
spellingShingle |
White matter lesions by magnetic resonance: an assessment between DWI and T2 FLAIR techniques Campos, Carla DWI T2 FLAIR Ressonância magnética Lesões da substância branca Diffusion T2 FLAIR MRI White matter disease |
title_short |
White matter lesions by magnetic resonance: an assessment between DWI and T2 FLAIR techniques |
title_full |
White matter lesions by magnetic resonance: an assessment between DWI and T2 FLAIR techniques |
title_fullStr |
White matter lesions by magnetic resonance: an assessment between DWI and T2 FLAIR techniques |
title_full_unstemmed |
White matter lesions by magnetic resonance: an assessment between DWI and T2 FLAIR techniques |
title_sort |
White matter lesions by magnetic resonance: an assessment between DWI and T2 FLAIR techniques |
author |
Campos, Carla |
author_facet |
Campos, Carla Silva, Raquel Ribeiro, Maria Margarida Lança, lu |
author_role |
author |
author2 |
Silva, Raquel Ribeiro, Maria Margarida Lança, lu |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Campos, Carla Silva, Raquel Ribeiro, Maria Margarida Lança, lu |
dc.subject.por.fl_str_mv |
DWI T2 FLAIR Ressonância magnética Lesões da substância branca Diffusion T2 FLAIR MRI White matter disease |
topic |
DWI T2 FLAIR Ressonância magnética Lesões da substância branca Diffusion T2 FLAIR MRI White matter disease |
description |
Objectives – To determine the sensitivity and specificity of diffusion-weighted (DWI) and Fluid-Attenuated Inversion Recovery (T2 FLAIR) in the evaluation of white matter lesions and to verify what is his extended complement in order to create a set of best practices in the MRI routine of the brain. Methodology – Was carried out a quantitative study with retrospective analysis. From the database, were selected 30 patients, 20 with and 10 without the disease. We obtained a sample of 60 images, including 30-weighted images of T2 FLAIR and 30 of DWI. Using the program Viewdex®, the set of images was observed by three observers. The images were assessed according to seven criteria: visibility, detection, consistency, location, size, margins of the lesion, and diagnostic capability. We used the calculation of sensitivity and specificity by ROC curves, as well as statistical analysis, namely, T-test, Kappa index, and Pearson’s correlation coefficient between the variables under study. Results – The sensitivity and specificity obtained for the weighted T2 FLAIR were higher (0,915 and 0,038 respectively) than the weighting DWI (0.08 and 0.100 respectively). There were no significant population variances. We obtained a high linear correlation between variables with an r value located between 0.8 and 0.99. There was considerable variability among observers. Conclusions – Although the values of sensitivity and specificity for DWI have been lower than expected, we suggest that this sequence should be included in the routine protocol of the brain to help the differential diagnosis with other pathologies. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-05-15 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.25758/set.594 oai:journals.ipl.pt:article/666 |
url |
https://doi.org/10.25758/set.594 |
identifier_str_mv |
oai:journals.ipl.pt:article/666 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://journals.ipl.pt/stecnologia/article/view/666 https://doi.org/10.25758/set.594 https://journals.ipl.pt/stecnologia/article/view/666/559 |
dc.rights.driver.fl_str_mv |
Direitos de Autor (c) 2022 Saúde & Tecnologia info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Direitos de Autor (c) 2022 Saúde & Tecnologia |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Escola Superior de Tecnologia da Saúde de Lisboa (Instituto Politécnico de Lisboa) |
publisher.none.fl_str_mv |
Escola Superior de Tecnologia da Saúde de Lisboa (Instituto Politécnico de Lisboa) |
dc.source.none.fl_str_mv |
Saúde e Tecnologia; No. 09 (2013): Maio 2013; 16-23 Saúde & Tecnologia; N.º 09 (2013): Maio 2013; 16-23 1646-9704 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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