Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®)

Detalhes bibliográficos
Autor(a) principal: Costa, Suzete
Data de Publicação: 2023
Outros Autores: Biscaia, José Luís, Horta, Maria Rute, Romano, Sónia, Guerreiro, José, Heudtlass, Peter, Cary, Maria, Romão, Mariana, Teixeira Rodrigues, António, Miranda, Ana, Martins, Ana Paula, Bento, Ana Sofia, Pereira, João, Mateus, Céu, Helling, Dennis K.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/59371
Resumo: Copyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
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spelling Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®)CollaborativeCommunity pharmacyEffectivenessHyperlipidemiaHypertensionPharmacy servicesPrimary carePublic health interventionsReal-worldTrialCopyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).There is evidence of the efficacy of collaborative health interventions with pharmacies and primary care providers but little of its real-world effectiveness. We aimed to assess the effectiveness and discuss the design and challenges of hypertension and hyperlipidemia management between pharmacies and primary care providers using real-world data exchange between providers and experimental bundled payment. This was a pragmatic, quasi-experimental controlled trial. We collected patient-level data from primary care prescription claims and Electronic Medical Record databases, a pharmacy claims database, and patient telephone surveys at several time points. The primary outcomes were changes in blood pressure and total cholesterol. We used matched controls with difference-in-differences estimators in a Generalized Linear Model (GLM) and controlled interrupted time series (CITS). We collected additional data for economic and qualitative studies. A total of 6 Primary Care Units, 20 pharmacies, and 203 patients entered the study. We were not able to observe significant differences in the effect of intervention vs. control. We experienced challenges that required creative strategies. This real-world trial was not able to show effectiveness, likely due to limitations in the primary care technology which affected the sample size. It offers, however, valuable lessons on methods, strategies, and data sources, paving the way for more real-world effectiveness trials to advance value-based healthcare.This trial was promoted by the Agrupamento dos Centros de Saúde (ACeS) (NHS Group of Primary Care Units) of the Baixo Mondego Region and the Associação Nacional das Farmácias (ANF) (Portuguese National Association of Pharmacies) and was funded by the ANF. Hartmann supplied blood pressure monitors to intervention pharmacies. Trial Registration Number: ISRCTN13410498. S.C. paid for the open-access publication fee for this manuscript.MDPIRepositório da Universidade de LisboaCosta, SuzeteBiscaia, José LuísHorta, Maria RuteRomano, SóniaGuerreiro, JoséHeudtlass, PeterCary, MariaRomão, MarianaTeixeira Rodrigues, AntónioMiranda, AnaMartins, Ana PaulaBento, Ana SofiaPereira, JoãoMateus, CéuHelling, Dennis K.2023-09-19T13:27:16Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/59371engInt J Environ Res Public Health. 2023 Aug 1;20(15):64961661-782710.3390/ijerph201564961660-4601info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:08:27Zoai:repositorio.ul.pt:10451/59371Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:09:18.276247Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®)
title Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®)
spellingShingle Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®)
Costa, Suzete
Collaborative
Community pharmacy
Effectiveness
Hyperlipidemia
Hypertension
Pharmacy services
Primary care
Public health interventions
Real-world
Trial
title_short Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®)
title_full Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®)
title_fullStr Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®)
title_full_unstemmed Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®)
title_sort Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®)
author Costa, Suzete
author_facet Costa, Suzete
Biscaia, José Luís
Horta, Maria Rute
Romano, Sónia
Guerreiro, José
Heudtlass, Peter
Cary, Maria
Romão, Mariana
Teixeira Rodrigues, António
Miranda, Ana
Martins, Ana Paula
Bento, Ana Sofia
Pereira, João
Mateus, Céu
Helling, Dennis K.
author_role author
author2 Biscaia, José Luís
Horta, Maria Rute
Romano, Sónia
Guerreiro, José
Heudtlass, Peter
Cary, Maria
Romão, Mariana
Teixeira Rodrigues, António
Miranda, Ana
Martins, Ana Paula
Bento, Ana Sofia
Pereira, João
Mateus, Céu
Helling, Dennis K.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Costa, Suzete
Biscaia, José Luís
Horta, Maria Rute
Romano, Sónia
Guerreiro, José
Heudtlass, Peter
Cary, Maria
Romão, Mariana
Teixeira Rodrigues, António
Miranda, Ana
Martins, Ana Paula
Bento, Ana Sofia
Pereira, João
Mateus, Céu
Helling, Dennis K.
dc.subject.por.fl_str_mv Collaborative
Community pharmacy
Effectiveness
Hyperlipidemia
Hypertension
Pharmacy services
Primary care
Public health interventions
Real-world
Trial
topic Collaborative
Community pharmacy
Effectiveness
Hyperlipidemia
Hypertension
Pharmacy services
Primary care
Public health interventions
Real-world
Trial
description Copyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
publishDate 2023
dc.date.none.fl_str_mv 2023-09-19T13:27:16Z
2023
2023-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/59371
url http://hdl.handle.net/10451/59371
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Int J Environ Res Public Health. 2023 Aug 1;20(15):6496
1661-7827
10.3390/ijerph20156496
1660-4601
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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