Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®)
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10451/59371 |
Resumo: | Copyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®)CollaborativeCommunity pharmacyEffectivenessHyperlipidemiaHypertensionPharmacy servicesPrimary carePublic health interventionsReal-worldTrialCopyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).There is evidence of the efficacy of collaborative health interventions with pharmacies and primary care providers but little of its real-world effectiveness. We aimed to assess the effectiveness and discuss the design and challenges of hypertension and hyperlipidemia management between pharmacies and primary care providers using real-world data exchange between providers and experimental bundled payment. This was a pragmatic, quasi-experimental controlled trial. We collected patient-level data from primary care prescription claims and Electronic Medical Record databases, a pharmacy claims database, and patient telephone surveys at several time points. The primary outcomes were changes in blood pressure and total cholesterol. We used matched controls with difference-in-differences estimators in a Generalized Linear Model (GLM) and controlled interrupted time series (CITS). We collected additional data for economic and qualitative studies. A total of 6 Primary Care Units, 20 pharmacies, and 203 patients entered the study. We were not able to observe significant differences in the effect of intervention vs. control. We experienced challenges that required creative strategies. This real-world trial was not able to show effectiveness, likely due to limitations in the primary care technology which affected the sample size. It offers, however, valuable lessons on methods, strategies, and data sources, paving the way for more real-world effectiveness trials to advance value-based healthcare.This trial was promoted by the Agrupamento dos Centros de Saúde (ACeS) (NHS Group of Primary Care Units) of the Baixo Mondego Region and the Associação Nacional das Farmácias (ANF) (Portuguese National Association of Pharmacies) and was funded by the ANF. Hartmann supplied blood pressure monitors to intervention pharmacies. Trial Registration Number: ISRCTN13410498. S.C. paid for the open-access publication fee for this manuscript.MDPIRepositório da Universidade de LisboaCosta, SuzeteBiscaia, José LuísHorta, Maria RuteRomano, SóniaGuerreiro, JoséHeudtlass, PeterCary, MariaRomão, MarianaTeixeira Rodrigues, AntónioMiranda, AnaMartins, Ana PaulaBento, Ana SofiaPereira, JoãoMateus, CéuHelling, Dennis K.2023-09-19T13:27:16Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/59371engInt J Environ Res Public Health. 2023 Aug 1;20(15):64961661-782710.3390/ijerph201564961660-4601info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:08:27Zoai:repositorio.ul.pt:10451/59371Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:09:18.276247Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®) |
title |
Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®) |
spellingShingle |
Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®) Costa, Suzete Collaborative Community pharmacy Effectiveness Hyperlipidemia Hypertension Pharmacy services Primary care Public health interventions Real-world Trial |
title_short |
Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®) |
title_full |
Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®) |
title_fullStr |
Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®) |
title_full_unstemmed |
Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®) |
title_sort |
Real-world effectiveness in hypertension and hyperlipidemia collaborative management between pharmacies and primary care in Portugal: a multicenter pragmatic controlled trial (USFarmácia®) |
author |
Costa, Suzete |
author_facet |
Costa, Suzete Biscaia, José Luís Horta, Maria Rute Romano, Sónia Guerreiro, José Heudtlass, Peter Cary, Maria Romão, Mariana Teixeira Rodrigues, António Miranda, Ana Martins, Ana Paula Bento, Ana Sofia Pereira, João Mateus, Céu Helling, Dennis K. |
author_role |
author |
author2 |
Biscaia, José Luís Horta, Maria Rute Romano, Sónia Guerreiro, José Heudtlass, Peter Cary, Maria Romão, Mariana Teixeira Rodrigues, António Miranda, Ana Martins, Ana Paula Bento, Ana Sofia Pereira, João Mateus, Céu Helling, Dennis K. |
author2_role |
author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
dc.contributor.author.fl_str_mv |
Costa, Suzete Biscaia, José Luís Horta, Maria Rute Romano, Sónia Guerreiro, José Heudtlass, Peter Cary, Maria Romão, Mariana Teixeira Rodrigues, António Miranda, Ana Martins, Ana Paula Bento, Ana Sofia Pereira, João Mateus, Céu Helling, Dennis K. |
dc.subject.por.fl_str_mv |
Collaborative Community pharmacy Effectiveness Hyperlipidemia Hypertension Pharmacy services Primary care Public health interventions Real-world Trial |
topic |
Collaborative Community pharmacy Effectiveness Hyperlipidemia Hypertension Pharmacy services Primary care Public health interventions Real-world Trial |
description |
Copyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-09-19T13:27:16Z 2023 2023-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10451/59371 |
url |
http://hdl.handle.net/10451/59371 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Int J Environ Res Public Health. 2023 Aug 1;20(15):6496 1661-7827 10.3390/ijerph20156496 1660-4601 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799134648791465984 |