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spelling Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromiumHexavalent chromiumBiomonitoringOccupational exposureExhaled breath condensateWeldingElectroplatingEffect markersMulticenter studyHorizon 2020 - Grant agreement no. 733032The EU human biomonitoring initiative, HBM4EU, aims to coordinate and advance human biomonitoring (HBM) across Europe. Within its remit, the project is gathering new, policy-relevant, EU-wide data on occupational exposure to relevant priority chemicals and developing new approaches for occupational biomonitoring. In this manuscript, the hexavalent chromium (Cr(VI)) study design is presented as the first example of this HBM4EU approach. This study involves eight European countries and plans to recruit 400 workers performing Cr(VI) surface treatment e.g. electroplating or stainless steel welding activities. The aim is to collect new data on current occupational exposure to Cr(VI) in Europe and to test new methods for Cr biomonitoring, specifically the analysis of Cr(VI) in exhaled breath condensate (EBC) and Cr in red blood cells (RBC) in addition to traditional urinary total Cr analyses. Furthermore, exposure data will be complemented with early biological effects data, including genetic and epigenetic effects. Personal air samples and wipe samples are collected in parallel to help to inform the biomonitoring results. We present standard operational procedures (SOPs) to support the harmonized methodologies for the collection of occupational hygiene and HBM samples in different countries.ElsevierRCIPLSantonen, TiinaAlimonti, AlessandroBocca, BeatriceDuca, Radu CorneliuGalea, Karen S.Godderis, LodeGöen, ThomasGomes, BrunoHanser, OgierIavicoli, IvoJanasik, BeataJones, KateKiilunen, MirjaKoch, Holger M.Leese, ElizabethLeso, VerusckaLouro, HenriquetaNdaw, SophiePorras, Simo P.Robert, AlainRuggieri, FlaviaScheepers, Paul T. J.Silva, Maria J.Viegas, SusanaWasowicz, WojciechCastano, ArgeliaSepai, Ovnair2019-07-17T11:51:17Z2019-102019-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/10306engSantonen T, Alimonti A, Bocca B, Duca RC, Galea KS, Viegas S, et al. Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium. Environ Res. 2019;177:108583.10.1016/j.envres.2019.108583info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T10:00:05Zoai:repositorio.ipl.pt:10400.21/10306Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:18:45.451127Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium
title Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium
spellingShingle Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium
Santonen, Tiina
Hexavalent chromium
Biomonitoring
Occupational exposure
Exhaled breath condensate
Welding
Electroplating
Effect markers
Multicenter study
title_short Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium
title_full Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium
title_fullStr Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium
title_full_unstemmed Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium
title_sort Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium
author Santonen, Tiina
author_facet Santonen, Tiina
Alimonti, Alessandro
Bocca, Beatrice
Duca, Radu Corneliu
Galea, Karen S.
Godderis, Lode
Göen, Thomas
Gomes, Bruno
Hanser, Ogier
Iavicoli, Ivo
Janasik, Beata
Jones, Kate
Kiilunen, Mirja
Koch, Holger M.
Leese, Elizabeth
Leso, Veruscka
Louro, Henriqueta
Ndaw, Sophie
Porras, Simo P.
Robert, Alain
Ruggieri, Flavia
Scheepers, Paul T. J.
Silva, Maria J.
Viegas, Susana
Wasowicz, Wojciech
Castano, Argelia
Sepai, Ovnair
author_role author
author2 Alimonti, Alessandro
Bocca, Beatrice
Duca, Radu Corneliu
Galea, Karen S.
Godderis, Lode
Göen, Thomas
Gomes, Bruno
Hanser, Ogier
Iavicoli, Ivo
Janasik, Beata
Jones, Kate
Kiilunen, Mirja
Koch, Holger M.
Leese, Elizabeth
Leso, Veruscka
Louro, Henriqueta
Ndaw, Sophie
Porras, Simo P.
Robert, Alain
Ruggieri, Flavia
Scheepers, Paul T. J.
Silva, Maria J.
Viegas, Susana
Wasowicz, Wojciech
Castano, Argelia
Sepai, Ovnair
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv RCIPL
dc.contributor.author.fl_str_mv Santonen, Tiina
Alimonti, Alessandro
Bocca, Beatrice
Duca, Radu Corneliu
Galea, Karen S.
Godderis, Lode
Göen, Thomas
Gomes, Bruno
Hanser, Ogier
Iavicoli, Ivo
Janasik, Beata
Jones, Kate
Kiilunen, Mirja
Koch, Holger M.
Leese, Elizabeth
Leso, Veruscka
Louro, Henriqueta
Ndaw, Sophie
Porras, Simo P.
Robert, Alain
Ruggieri, Flavia
Scheepers, Paul T. J.
Silva, Maria J.
Viegas, Susana
Wasowicz, Wojciech
Castano, Argelia
Sepai, Ovnair
dc.subject.por.fl_str_mv Hexavalent chromium
Biomonitoring
Occupational exposure
Exhaled breath condensate
Welding
Electroplating
Effect markers
Multicenter study
topic Hexavalent chromium
Biomonitoring
Occupational exposure
Exhaled breath condensate
Welding
Electroplating
Effect markers
Multicenter study
description Horizon 2020 - Grant agreement no. 733032
publishDate 2019
dc.date.none.fl_str_mv 2019-07-17T11:51:17Z
2019-10
2019-10-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.21/10306
url http://hdl.handle.net/10400.21/10306
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Santonen T, Alimonti A, Bocca B, Duca RC, Galea KS, Viegas S, et al. Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium. Environ Res. 2019;177:108583.
10.1016/j.envres.2019.108583
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
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instacron_str RCAAP
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