HBM4EU chromates study
| Autor(a) principal: | |
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| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10362/125826 |
Resumo: | Crown Copyright © 2021. Published by Elsevier Inc. All rights reserved. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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HBM4EU chromates studyoverall results and recommendations for the biomonitoring of occupational exposure to hexavalent chromiumBiomonitoringElectroplatingHexavalent chromiumOccupational exposureWeldingEnvironmental Science(all)BiochemistryCrown Copyright © 2021. Published by Elsevier Inc. All rights reserved.Exposure to hexavalent chromium [Cr(VI)] may occur in several occupational activities, e.g., welding, Cr(VI) electroplating and other surface treatment processes. The aim of this study was to provide EU relevant data on occupational Cr(VI) exposure to support the regulatory risk assessment and decision-making. In addition, the capability and validity of different biomarkers for the assessment of Cr(VI) exposure were evaluated. The study involved nine European countries and involved 399 workers in different industry sectors with exposures to Cr(VI) such as welding, bath plating, applying or removing paint and other tasks. We also studied 203 controls to establish a background in workers with no direct exposure to Cr(VI). We applied a cross-sectional study design and used chromium in urine as the primary biomonitoring method for Cr(VI) exposure. Additionally, we studied the use of red blood cells (RBC) and exhaled breath condensate (EBC) for biomonitoring of exposure to Cr(VI). Personal measurements were used to study exposure to inhalable and respirable Cr(VI) by personal air sampling. Dermal exposure was studied by taking hand wipe samples. The highest internal exposures were observed in the use of Cr(VI) in electrolytic bath plating. In stainless steel welding the internal Cr exposure was clearly lower when compared to plating activities. We observed a high correlation between chromium urinary levels and air Cr(VI) or dermal total Cr exposure. Urinary chromium showed its value as a first approach for the assessment of total, internal exposure. Correlations between urinary chromium and Cr(VI) in EBC and Cr in RBC were low, probably due to differences in kinetics and indicating that these biomonitoring approaches may not be interchangeable but rather complementary. This study showed that occupational biomonitoring studies can be conducted successfully by multi-national collaboration and provide relevant information to support policy actions aiming to reduce occupational exposure to chemicals.Centre for Toxicogenomics and Human Health (ToxOmics)NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Comprehensive Health Research Centre (CHRC) - Pólo ENSPEscola Nacional de Saúde Pública (ENSP)Centro de Investigação em Saúde Pública (CISP/PHRC)RUNHBM4EU chromates study teamSantonen, TiinaPorras, Simo PBocca, BeatriceBousoumah, RadiaDuca, Radu CorneliuGalea, Karen SGodderis, LodeGöen, ThomasHardy, EmilieIavicoli, IvoJanasik, BeataJones, KateLeese, ElizabethLeso, VerusckaLouro, HenriquetaMajery, NicoleNdaw, SophiePinhal, HermíniaRuggieri, FlaviaSilva, Maria Jvan Nieuwenhuyse, AnVerdonck, JelleViegas, SusanaWasowicz, WojciechSepai, OvnairScheepers, Paul T JCosta Gomes, Bruno2021-10-09T04:58:39Z2022-032022-03-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/125826eng0013-9351PURE: 34159881https://doi.org/10.1016/j.envres.2021.111984info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-10-21T01:36:12Zoai:run.unl.pt:10362/125826Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-10-21T01:36:12Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
HBM4EU chromates study overall results and recommendations for the biomonitoring of occupational exposure to hexavalent chromium |
| title |
HBM4EU chromates study |
| spellingShingle |
HBM4EU chromates study HBM4EU chromates study team Biomonitoring Electroplating Hexavalent chromium Occupational exposure Welding Environmental Science(all) Biochemistry |
| title_short |
HBM4EU chromates study |
| title_full |
HBM4EU chromates study |
| title_fullStr |
HBM4EU chromates study |
| title_full_unstemmed |
HBM4EU chromates study |
| title_sort |
HBM4EU chromates study |
| author |
HBM4EU chromates study team |
| author_facet |
HBM4EU chromates study team Santonen, Tiina Porras, Simo P Bocca, Beatrice Bousoumah, Radia Duca, Radu Corneliu Galea, Karen S Godderis, Lode Göen, Thomas Hardy, Emilie Iavicoli, Ivo Janasik, Beata Jones, Kate Leese, Elizabeth Leso, Veruscka Louro, Henriqueta Majery, Nicole Ndaw, Sophie Pinhal, Hermínia Ruggieri, Flavia Silva, Maria J van Nieuwenhuyse, An Verdonck, Jelle Viegas, Susana Wasowicz, Wojciech Sepai, Ovnair Scheepers, Paul T J Costa Gomes, Bruno |
| author_role |
author |
| author2 |
Santonen, Tiina Porras, Simo P Bocca, Beatrice Bousoumah, Radia Duca, Radu Corneliu Galea, Karen S Godderis, Lode Göen, Thomas Hardy, Emilie Iavicoli, Ivo Janasik, Beata Jones, Kate Leese, Elizabeth Leso, Veruscka Louro, Henriqueta Majery, Nicole Ndaw, Sophie Pinhal, Hermínia Ruggieri, Flavia Silva, Maria J van Nieuwenhuyse, An Verdonck, Jelle Viegas, Susana Wasowicz, Wojciech Sepai, Ovnair Scheepers, Paul T J Costa Gomes, Bruno |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Centre for Toxicogenomics and Human Health (ToxOmics) NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) Comprehensive Health Research Centre (CHRC) - Pólo ENSP Escola Nacional de Saúde Pública (ENSP) Centro de Investigação em Saúde Pública (CISP/PHRC) RUN |
| dc.contributor.author.fl_str_mv |
HBM4EU chromates study team Santonen, Tiina Porras, Simo P Bocca, Beatrice Bousoumah, Radia Duca, Radu Corneliu Galea, Karen S Godderis, Lode Göen, Thomas Hardy, Emilie Iavicoli, Ivo Janasik, Beata Jones, Kate Leese, Elizabeth Leso, Veruscka Louro, Henriqueta Majery, Nicole Ndaw, Sophie Pinhal, Hermínia Ruggieri, Flavia Silva, Maria J van Nieuwenhuyse, An Verdonck, Jelle Viegas, Susana Wasowicz, Wojciech Sepai, Ovnair Scheepers, Paul T J Costa Gomes, Bruno |
| dc.subject.por.fl_str_mv |
Biomonitoring Electroplating Hexavalent chromium Occupational exposure Welding Environmental Science(all) Biochemistry |
| topic |
Biomonitoring Electroplating Hexavalent chromium Occupational exposure Welding Environmental Science(all) Biochemistry |
| description |
Crown Copyright © 2021. Published by Elsevier Inc. All rights reserved. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021-10-09T04:58:39Z 2022-03 2022-03-01T00:00:00Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/125826 |
| url |
http://hdl.handle.net/10362/125826 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
0013-9351 PURE: 34159881 https://doi.org/10.1016/j.envres.2021.111984 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
| instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
| instacron_str |
RCAAP |
| institution |
RCAAP |
| reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
| repository.mail.fl_str_mv |
mluisa.alvim@gmail.com |
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1817545824694960128 |