Epidural Analgesia in the Surgical Correction of Pediatric Scoliosis

Detalhes bibliográficos
Autor(a) principal: Nóbrega, Sónia Dória
Data de Publicação: 2020
Outros Autores: Ferreira, Ana, Ramos, Sara
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25751/rspa.19016
Resumo: Introduction: Pediatric scoliosis surgery aims at stopping the progression of the disease and improving quality of life, however it is associated with a severely painful postoperative period. In 2016, we implemented a clinical protocol with postoperative continuous epidural analgesia, by one or two epidural catheters placed by the surgeon at the end of surgery. The aim of our study was to evaluate the analgesic effectiveness of the epidural protocol up to 72 hours after surgery, the incidence of adverse events and the length of Intensive Care Unit (ICU) stay. Methods: A retrospective analysis was performed by consulting the patients’ clinical files, comparing two groups: Alfentanil group (AG)- 25 patients with systemic opioid analgesia through an alfentanil intravenous infusion - and Epidural group (EG) - 21 patients with epidural ropivacaine and morphine infusion. Data were analyzed using SPSS® , using Nonparametric Mann-Whitney test, Fisher’s exact test and Spearman’s correlation coefficient. A level of significance α=0.05 was considered. Results: The mean pain scores (0-10 numeric rating scale) of the EG were statistically lower at immediate postoperative (-3), 24 hours (-5) and 48 hours (- 4) after surgery (p<0.001), as were the needs for rescue analgesia (p<0.001). There were fewer adverse events in the EG, not reaching statistical significance. ICU length of stay was statistically shorter with epidural analgesia (p<0.001). Conclusion: Epidural analgesia is an effective alternative to systemic opioid analgesia for pediatric scoliosis surgery. Prospective randomized studies are needed to confirm these results.
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spelling Epidural Analgesia in the Surgical Correction of Pediatric ScoliosisAnalgesia Epidural em Cirurgia de Escoliose em Idade PediátricaArtigo OriginalIntroduction: Pediatric scoliosis surgery aims at stopping the progression of the disease and improving quality of life, however it is associated with a severely painful postoperative period. In 2016, we implemented a clinical protocol with postoperative continuous epidural analgesia, by one or two epidural catheters placed by the surgeon at the end of surgery. The aim of our study was to evaluate the analgesic effectiveness of the epidural protocol up to 72 hours after surgery, the incidence of adverse events and the length of Intensive Care Unit (ICU) stay. Methods: A retrospective analysis was performed by consulting the patients’ clinical files, comparing two groups: Alfentanil group (AG)- 25 patients with systemic opioid analgesia through an alfentanil intravenous infusion - and Epidural group (EG) - 21 patients with epidural ropivacaine and morphine infusion. Data were analyzed using SPSS® , using Nonparametric Mann-Whitney test, Fisher’s exact test and Spearman’s correlation coefficient. A level of significance α=0.05 was considered. Results: The mean pain scores (0-10 numeric rating scale) of the EG were statistically lower at immediate postoperative (-3), 24 hours (-5) and 48 hours (- 4) after surgery (p<0.001), as were the needs for rescue analgesia (p<0.001). There were fewer adverse events in the EG, not reaching statistical significance. ICU length of stay was statistically shorter with epidural analgesia (p<0.001). Conclusion: Epidural analgesia is an effective alternative to systemic opioid analgesia for pediatric scoliosis surgery. Prospective randomized studies are needed to confirm these results.Introdução: A cirurgia de escoliose pediátrica, que visa interromper a progressão da doença e melhorar a qualidade de vida, está associada a dor pós-operatória intensa. Em 2016, implementámos a analgesia epidural no período pós-operatório, através de um ou dois cateteres epidurais, colocados pelo cirurgião no final da cirurgia. Os objetivos deste estudo foram avaliar a eficácia analgésica até 72 horas após a cirurgia, a incidência de eventos adversos e o tempo de permanência na Unidade de Cuidados Intensivos (UCI). Material e Métodos: Foi realizada uma análise retrospectiva comparando dois grupos: Grupo Alfentanil (AG) - 25 doentes com analgesia sistémica por perfusão endovenosa de alfentanil - e Grupo Epidural (EG) - 21 doentes com perfusão de ropivacaína e morfina via epidural. Os dados foram analisados através do SPSS®, utilizando o teste não paramétrico de Mann-Whitney, o teste exato de Fisher e o coeficiente de correlação de Spearman (nível de significância considerado α = 0,05). Resultados: Os scores de dor (escala numérica 0-10) foram inferiores no EG, no pós-operatório imediato (-3), 24 horas (-5) e 48 horas (-4) após a cirurgia (p<0,001). As necessidades de analgesia de resgate foram inferiores no EG (p<0,001). Houve menor incidência de eventos adversos no EG, não atingindo significância estatística. O tempo de internamento na UCI foi inferior no EG (p<0,001). Conclusão: A analgesia epidural é uma alternativa eficaz na cirurgia de escoliose pediátrica. São necessários estudos prospectivos randomizados para confirmar estes resultados.Sociedade Portuguesa de Anestesiologia2020-04-02T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25751/rspa.19016eng0871-6099Nóbrega, Sónia DóriaFerreira, AnaRamos, Sarainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-23T15:34:49Zoai:ojs.revistas.rcaap.pt:article/19016Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:04:16.944996Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Epidural Analgesia in the Surgical Correction of Pediatric Scoliosis
Analgesia Epidural em Cirurgia de Escoliose em Idade Pediátrica
title Epidural Analgesia in the Surgical Correction of Pediatric Scoliosis
spellingShingle Epidural Analgesia in the Surgical Correction of Pediatric Scoliosis
Nóbrega, Sónia Dória
Artigo Original
title_short Epidural Analgesia in the Surgical Correction of Pediatric Scoliosis
title_full Epidural Analgesia in the Surgical Correction of Pediatric Scoliosis
title_fullStr Epidural Analgesia in the Surgical Correction of Pediatric Scoliosis
title_full_unstemmed Epidural Analgesia in the Surgical Correction of Pediatric Scoliosis
title_sort Epidural Analgesia in the Surgical Correction of Pediatric Scoliosis
author Nóbrega, Sónia Dória
author_facet Nóbrega, Sónia Dória
Ferreira, Ana
Ramos, Sara
author_role author
author2 Ferreira, Ana
Ramos, Sara
author2_role author
author
dc.contributor.author.fl_str_mv Nóbrega, Sónia Dória
Ferreira, Ana
Ramos, Sara
dc.subject.por.fl_str_mv Artigo Original
topic Artigo Original
description Introduction: Pediatric scoliosis surgery aims at stopping the progression of the disease and improving quality of life, however it is associated with a severely painful postoperative period. In 2016, we implemented a clinical protocol with postoperative continuous epidural analgesia, by one or two epidural catheters placed by the surgeon at the end of surgery. The aim of our study was to evaluate the analgesic effectiveness of the epidural protocol up to 72 hours after surgery, the incidence of adverse events and the length of Intensive Care Unit (ICU) stay. Methods: A retrospective analysis was performed by consulting the patients’ clinical files, comparing two groups: Alfentanil group (AG)- 25 patients with systemic opioid analgesia through an alfentanil intravenous infusion - and Epidural group (EG) - 21 patients with epidural ropivacaine and morphine infusion. Data were analyzed using SPSS® , using Nonparametric Mann-Whitney test, Fisher’s exact test and Spearman’s correlation coefficient. A level of significance α=0.05 was considered. Results: The mean pain scores (0-10 numeric rating scale) of the EG were statistically lower at immediate postoperative (-3), 24 hours (-5) and 48 hours (- 4) after surgery (p<0.001), as were the needs for rescue analgesia (p<0.001). There were fewer adverse events in the EG, not reaching statistical significance. ICU length of stay was statistically shorter with epidural analgesia (p<0.001). Conclusion: Epidural analgesia is an effective alternative to systemic opioid analgesia for pediatric scoliosis surgery. Prospective randomized studies are needed to confirm these results.
publishDate 2020
dc.date.none.fl_str_mv 2020-04-02T00:00:00Z
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