Monkeypox: from a neglected tropical disease to a public health threat

Detalhes bibliográficos
Autor(a) principal: Antunes, Francisco
Data de Publicação: 2022
Outros Autores: Cordeiro, Rita, Virgolino, Ana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/54748
Resumo: Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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spelling Monkeypox: from a neglected tropical disease to a public health threatZoonosisMonkeypox virusEmerging infectious diseasesWest and Central Africa2022 outbreakCopyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).Since the first case of human monkeypox was diagnosed in 1970, the disease remained endemic in several countries in West and Central Africa. In 1996, there was a sudden increase in cases in the Democratic Republic of Congo (DRC), and since 2017 an ongoing outbreak in Nigeria took place, probably related to the population growth, human invasion of MPXV animal habitat reservoirs, and the waning of the cross-protection offered from smallpox immunization, later ending in 1980. Since May 2022, an unprecedented outbreak of human monkeypox has rapidly spread around the world, outside endemic regions of Africa, through new modes of transmission, showing differences in clinical features compared with previous reports. The 2022 MPXV strain belongs to the clade of West Africa but diverges from the original strain, making the virus more transmissible. The authors review the main milestones in more than 50 years of history of human monkeypox, from a rare viral zoonotic infection to a public health emergency.The writing of this manuscript received the support of Fundação para a Ciência e a Tecnologia, grant numbers UIDB/04295/2020 and UIDP/04295/2020.MDPIRepositório da Universidade de LisboaAntunes, FranciscoCordeiro, RitaVirgolino, Ana2022-10-12T14:49:55Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/54748engAntunes, F.; Cordeiro, R.; Virgolino, A. Monkeypox: From A Neglected Tropical Disease to a Public Health Threat. Infect. Dis. Rep. 2022, 14, 772-7832036-743010.3390/idr140500792036-7449info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:01:19Zoai:repositorio.ul.pt:10451/54748Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:05:30.996810Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Monkeypox: from a neglected tropical disease to a public health threat
title Monkeypox: from a neglected tropical disease to a public health threat
spellingShingle Monkeypox: from a neglected tropical disease to a public health threat
Antunes, Francisco
Zoonosis
Monkeypox virus
Emerging infectious diseases
West and Central Africa
2022 outbreak
title_short Monkeypox: from a neglected tropical disease to a public health threat
title_full Monkeypox: from a neglected tropical disease to a public health threat
title_fullStr Monkeypox: from a neglected tropical disease to a public health threat
title_full_unstemmed Monkeypox: from a neglected tropical disease to a public health threat
title_sort Monkeypox: from a neglected tropical disease to a public health threat
author Antunes, Francisco
author_facet Antunes, Francisco
Cordeiro, Rita
Virgolino, Ana
author_role author
author2 Cordeiro, Rita
Virgolino, Ana
author2_role author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Antunes, Francisco
Cordeiro, Rita
Virgolino, Ana
dc.subject.por.fl_str_mv Zoonosis
Monkeypox virus
Emerging infectious diseases
West and Central Africa
2022 outbreak
topic Zoonosis
Monkeypox virus
Emerging infectious diseases
West and Central Africa
2022 outbreak
description Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
publishDate 2022
dc.date.none.fl_str_mv 2022-10-12T14:49:55Z
2022
2022-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/54748
url http://hdl.handle.net/10451/54748
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Antunes, F.; Cordeiro, R.; Virgolino, A. Monkeypox: From A Neglected Tropical Disease to a Public Health Threat. Infect. Dis. Rep. 2022, 14, 772-783
2036-7430
10.3390/idr14050079
2036-7449
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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