Assessment of the BD MGIT TBc identification test for the detection of mycobacterium tuberculosis complex in a network of mycobacteriology laboratories

Detalhes bibliográficos
Autor(a) principal: Machado, Diana
Data de Publicação: 2014
Outros Autores: Ramos, Jorge, Couto, Isabel, Cadir, Nureisha, Narciso, Inácio, Coelho, Elizabeth, Viegas, Sofia, Viveiros, Miguel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/116796
Resumo: WOS:000330695600001
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spelling Assessment of the BD MGIT TBc identification test for the detection of mycobacterium tuberculosis complex in a network of mycobacteriology laboratoriesBiochemistry, Genetics and Molecular Biology(all)Immunology and Microbiology(all)Infectious DiseasesSDG 3 - Good Health and Well-beingWOS:000330695600001We evaluate the performance of the TBcID assay in a panel of 100 acid-fast bacilli cultures. Sixty-four isolates were TBcID positive for Mycobacterium tuberculosis complex (MTBC), whereas 36 gave negative results. These included 28 nontuberculous mycobacteria, one nonmycobacterial isolate, one M. tuberculosis, and six M. bovis BCG strains. This corresponds to a sensitivity of 90.14%, specificity of 100%, and positive and negative predictive values of 100% and 80.55%, respectively. The test is rapid, easy to perform and interpret, and does not require sample preparation or instrumentation. However, a negative result does not exclude the presence of a strain belonging to MTBC, especially when mutations in mpb64 gene are present or some M. bovis BCG strains are isolated. The TBcID showed potential to assist in the identification of MTBC when the implementation and usage of molecular methods are often not possible, principally in resource-limited countries.Instituto de Higiene e Medicina Tropical (IHMT)Centro de Malária e outras Doenças Tropicais (CMDT)RUNMachado, DianaRamos, JorgeCouto, IsabelCadir, NureishaNarciso, InácioCoelho, ElizabethViegas, SofiaViveiros, Miguel2021-05-03T22:29:03Z20142014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article7application/pdfhttp://hdl.handle.net/10362/116796eng2314-6133PURE: 1235067https://doi.org/10.1155/2014/398108info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:59:34Zoai:run.unl.pt:10362/116796Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:43:17.236613Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Assessment of the BD MGIT TBc identification test for the detection of mycobacterium tuberculosis complex in a network of mycobacteriology laboratories
title Assessment of the BD MGIT TBc identification test for the detection of mycobacterium tuberculosis complex in a network of mycobacteriology laboratories
spellingShingle Assessment of the BD MGIT TBc identification test for the detection of mycobacterium tuberculosis complex in a network of mycobacteriology laboratories
Machado, Diana
Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)
Infectious Diseases
SDG 3 - Good Health and Well-being
title_short Assessment of the BD MGIT TBc identification test for the detection of mycobacterium tuberculosis complex in a network of mycobacteriology laboratories
title_full Assessment of the BD MGIT TBc identification test for the detection of mycobacterium tuberculosis complex in a network of mycobacteriology laboratories
title_fullStr Assessment of the BD MGIT TBc identification test for the detection of mycobacterium tuberculosis complex in a network of mycobacteriology laboratories
title_full_unstemmed Assessment of the BD MGIT TBc identification test for the detection of mycobacterium tuberculosis complex in a network of mycobacteriology laboratories
title_sort Assessment of the BD MGIT TBc identification test for the detection of mycobacterium tuberculosis complex in a network of mycobacteriology laboratories
author Machado, Diana
author_facet Machado, Diana
Ramos, Jorge
Couto, Isabel
Cadir, Nureisha
Narciso, Inácio
Coelho, Elizabeth
Viegas, Sofia
Viveiros, Miguel
author_role author
author2 Ramos, Jorge
Couto, Isabel
Cadir, Nureisha
Narciso, Inácio
Coelho, Elizabeth
Viegas, Sofia
Viveiros, Miguel
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Instituto de Higiene e Medicina Tropical (IHMT)
Centro de Malária e outras Doenças Tropicais (CMDT)
RUN
dc.contributor.author.fl_str_mv Machado, Diana
Ramos, Jorge
Couto, Isabel
Cadir, Nureisha
Narciso, Inácio
Coelho, Elizabeth
Viegas, Sofia
Viveiros, Miguel
dc.subject.por.fl_str_mv Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)
Infectious Diseases
SDG 3 - Good Health and Well-being
topic Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)
Infectious Diseases
SDG 3 - Good Health and Well-being
description WOS:000330695600001
publishDate 2014
dc.date.none.fl_str_mv 2014
2014-01-01T00:00:00Z
2021-05-03T22:29:03Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/116796
url http://hdl.handle.net/10362/116796
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2314-6133
PURE: 1235067
https://doi.org/10.1155/2014/398108
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 7
application/pdf
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instacron:RCAAP
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