Treatment of Hepatitis C Virus Infection in Kidney Transplant Recipients: Case Report

Detalhes bibliográficos
Autor(a) principal: Caeiro, F
Data de Publicação: 2011
Outros Autores: Baptista, V, Rodrigues, N, Carvalho, D, Aires, I, Remédio, F, Nolasco, F
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.17/614
Resumo: Chronic hepatitis C virus (HCV) infection exists in a large proportion of patients undergoing renal transplantation. Nowadays it is not considered to be an absolute contraindication to transplantation; however, it is associated with an increased risk for the patient and accounts for a shorter half-life of the renal allograft. We present three transplant recipients who displayed serious hepatic dysfunction after renal transplantation due to an HCV infection. In two of these cases, the liver biopsies established the diagnosis of FCH. In the third case, the liver biopsy was compatible with the early stages of FCH. All patients were started on peg-interferon alfa 2-b and ribavirin with subsequent normalization of hepatic function and early complete viral responses.
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spelling Treatment of Hepatitis C Virus Infection in Kidney Transplant Recipients: Case ReportAntiviraisHepatite CBiópsiaInterferão AlfaTransplantação de RimFígadoProteínas RecombinantesHCC NEFChronic hepatitis C virus (HCV) infection exists in a large proportion of patients undergoing renal transplantation. Nowadays it is not considered to be an absolute contraindication to transplantation; however, it is associated with an increased risk for the patient and accounts for a shorter half-life of the renal allograft. We present three transplant recipients who displayed serious hepatic dysfunction after renal transplantation due to an HCV infection. In two of these cases, the liver biopsies established the diagnosis of FCH. In the third case, the liver biopsy was compatible with the early stages of FCH. All patients were started on peg-interferon alfa 2-b and ribavirin with subsequent normalization of hepatic function and early complete viral responses.ElsevierRepositório do Centro Hospitalar Universitário de Lisboa Central, EPECaeiro, FBaptista, VRodrigues, NCarvalho, DAires, IRemédio, FNolasco, F2012-08-07T15:16:19Z20112011-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/614engTransplant Proc. 2011 Jan-Feb;43(1):259-62.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:27:23Zoai:repositorio.chlc.min-saude.pt:10400.17/614Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:18:21.685110Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Treatment of Hepatitis C Virus Infection in Kidney Transplant Recipients: Case Report
title Treatment of Hepatitis C Virus Infection in Kidney Transplant Recipients: Case Report
spellingShingle Treatment of Hepatitis C Virus Infection in Kidney Transplant Recipients: Case Report
Caeiro, F
Antivirais
Hepatite C
Biópsia
Interferão Alfa
Transplantação de Rim
Fígado
Proteínas Recombinantes
HCC NEF
title_short Treatment of Hepatitis C Virus Infection in Kidney Transplant Recipients: Case Report
title_full Treatment of Hepatitis C Virus Infection in Kidney Transplant Recipients: Case Report
title_fullStr Treatment of Hepatitis C Virus Infection in Kidney Transplant Recipients: Case Report
title_full_unstemmed Treatment of Hepatitis C Virus Infection in Kidney Transplant Recipients: Case Report
title_sort Treatment of Hepatitis C Virus Infection in Kidney Transplant Recipients: Case Report
author Caeiro, F
author_facet Caeiro, F
Baptista, V
Rodrigues, N
Carvalho, D
Aires, I
Remédio, F
Nolasco, F
author_role author
author2 Baptista, V
Rodrigues, N
Carvalho, D
Aires, I
Remédio, F
Nolasco, F
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE
dc.contributor.author.fl_str_mv Caeiro, F
Baptista, V
Rodrigues, N
Carvalho, D
Aires, I
Remédio, F
Nolasco, F
dc.subject.por.fl_str_mv Antivirais
Hepatite C
Biópsia
Interferão Alfa
Transplantação de Rim
Fígado
Proteínas Recombinantes
HCC NEF
topic Antivirais
Hepatite C
Biópsia
Interferão Alfa
Transplantação de Rim
Fígado
Proteínas Recombinantes
HCC NEF
description Chronic hepatitis C virus (HCV) infection exists in a large proportion of patients undergoing renal transplantation. Nowadays it is not considered to be an absolute contraindication to transplantation; however, it is associated with an increased risk for the patient and accounts for a shorter half-life of the renal allograft. We present three transplant recipients who displayed serious hepatic dysfunction after renal transplantation due to an HCV infection. In two of these cases, the liver biopsies established the diagnosis of FCH. In the third case, the liver biopsy was compatible with the early stages of FCH. All patients were started on peg-interferon alfa 2-b and ribavirin with subsequent normalization of hepatic function and early complete viral responses.
publishDate 2011
dc.date.none.fl_str_mv 2011
2011-01-01T00:00:00Z
2012-08-07T15:16:19Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.17/614
url http://hdl.handle.net/10400.17/614
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Transplant Proc. 2011 Jan-Feb;43(1):259-62.
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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