PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURE
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
DOI: | 10.29021/spdv.70.3.5 |
Texto Completo: | https://doi.org/10.29021/spdv.70.3.5 |
Resumo: | Psoriasis is a chronic systemic T-cell-mediated inflammatory disease with high morbidity. Psoriasis’s investigation has been intense, improving knowledge on physiopathology and leading to new biologic therapies for moderate and severe psoriasis’s treatment. This review will focus the present and the future of anti-cytokine therapies, beside the class of tumor necrosis factor-α (TNF-α) blockers.KEYWORDS – Antibodies, Monoclonal; Biological agents; Dermatologic agents; Psoriasis. |
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PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURETRATAMENTO DA PSORÍASE COM AGENTES BIOLÓGICOS: PARA ALÉM DOS INIBIDORES DO TNF α – O PRESENTE E O FUTUROPsoriasis is a chronic systemic T-cell-mediated inflammatory disease with high morbidity. Psoriasis’s investigation has been intense, improving knowledge on physiopathology and leading to new biologic therapies for moderate and severe psoriasis’s treatment. This review will focus the present and the future of anti-cytokine therapies, beside the class of tumor necrosis factor-α (TNF-α) blockers.KEYWORDS – Antibodies, Monoclonal; Biological agents; Dermatologic agents; Psoriasis.A psoríase é uma doença inflamatória crónica multissistémica, mediada por células T, com elevado grau de morbilidade. A investigação na área da psoríase tem sido intensa, resultando num conhecimento mais porme- norizado da sua patogenia, e consequente desenvolvimento de novas terapêuticas biológicas. Esta revisão focará o presente e o futuro dos agentes biológicos moduladores de citoquinas que não pertencem à classe dos inibidores do factor de necrose tumoral-α (TNF-α).PALAVRAS-CHAVE – Anticorpos monoclonais; Psoríase; Agentes biológicos; Ustekinumab.Sociedade Portuguesa de Dermatologia e Venereologia2013-01-13T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.70.3.5oai:ojs.revista.spdv.com.pt:article/5Journal of the Portuguese Society of Dermatology and Venereology; Vol 70 No 3 (2012): Julho - Setembro; 299Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 70 n. 3 (2012): Julho - Setembro; 2992182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/5https://doi.org/10.29021/spdv.70.3.5https://revista.spdv.com.pt/index.php/spdv/article/view/5/5Carvalho, SandrinaTorres, TiagoSelores, Manuelainfo:eu-repo/semantics/openAccess2022-10-06T12:34:34Zoai:ojs.revista.spdv.com.pt:article/5Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:10:36.731770Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURE TRATAMENTO DA PSORÍASE COM AGENTES BIOLÓGICOS: PARA ALÉM DOS INIBIDORES DO TNF α – O PRESENTE E O FUTURO |
title |
PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURE |
spellingShingle |
PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURE PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURE Carvalho, Sandrina Carvalho, Sandrina |
title_short |
PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURE |
title_full |
PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURE |
title_fullStr |
PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURE PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURE |
title_full_unstemmed |
PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURE PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURE |
title_sort |
PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURE |
author |
Carvalho, Sandrina |
author_facet |
Carvalho, Sandrina Carvalho, Sandrina Torres, Tiago Selores, Manuela Torres, Tiago Selores, Manuela |
author_role |
author |
author2 |
Torres, Tiago Selores, Manuela |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Carvalho, Sandrina Torres, Tiago Selores, Manuela |
description |
Psoriasis is a chronic systemic T-cell-mediated inflammatory disease with high morbidity. Psoriasis’s investigation has been intense, improving knowledge on physiopathology and leading to new biologic therapies for moderate and severe psoriasis’s treatment. This review will focus the present and the future of anti-cytokine therapies, beside the class of tumor necrosis factor-α (TNF-α) blockers.KEYWORDS – Antibodies, Monoclonal; Biological agents; Dermatologic agents; Psoriasis. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-01-13T00:00:00Z |
dc.type.driver.fl_str_mv |
journal article info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.29021/spdv.70.3.5 oai:ojs.revista.spdv.com.pt:article/5 |
url |
https://doi.org/10.29021/spdv.70.3.5 |
identifier_str_mv |
oai:ojs.revista.spdv.com.pt:article/5 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revista.spdv.com.pt/index.php/spdv/article/view/5 https://doi.org/10.29021/spdv.70.3.5 https://revista.spdv.com.pt/index.php/spdv/article/view/5/5 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
dc.source.none.fl_str_mv |
Journal of the Portuguese Society of Dermatology and Venereology; Vol 70 No 3 (2012): Julho - Setembro; 299 Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 70 n. 3 (2012): Julho - Setembro; 299 2182-2409 2182-2395 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
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1822183363804397568 |
dc.identifier.doi.none.fl_str_mv |
10.29021/spdv.70.3.5 |