Cell-adhesion Molecules as Key Mechanisms of Tumor Invasion:The Case of Breast Cancer

Detalhes bibliográficos
Autor(a) principal: Botelho, Mónica
Data de Publicação: 2022
Outros Autores: Luís, Carla, Soares, Raquel, Fernandes, Rúben
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/8523
Resumo: Cancer is a major health problem worldwide and the second leading cause of death following cardiovascular diseases. Breast cancer is the leading cause of mortality and morbidity among women and one of the most common malignant neoplasms prompt to metastatic disease. In the present review, the mechanisms of the major cell adhesion molecules involved in tumor invasion are discussed, focusing on the case of breast cancer. A non-systematic updated revision of the literature was performed in order to assemble information regarding the expression of the adhesion cell molecules associated with metastasis.
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spelling Cell-adhesion Molecules as Key Mechanisms of Tumor Invasion:The Case of Breast CancerBreast CancerMetastasisCell adhesion moleculesCadherinsSelectinsIntegrinsIgcamCancer is a major health problem worldwide and the second leading cause of death following cardiovascular diseases. Breast cancer is the leading cause of mortality and morbidity among women and one of the most common malignant neoplasms prompt to metastatic disease. In the present review, the mechanisms of the major cell adhesion molecules involved in tumor invasion are discussed, focusing on the case of breast cancer. A non-systematic updated revision of the literature was performed in order to assemble information regarding the expression of the adhesion cell molecules associated with metastasis.This work was supported by a scholarship with the reference SFRH/BD/146489/2019.Bentham Science PublishersRepositório Científico do Instituto Nacional de SaúdeBotelho, MónicaLuís, CarlaSoares, RaquelFernandes, Rúben2023-02-10T16:09:10Z2022-03-102022-03-10T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/8523engCurr Mol Med. 2023;23(2):147-160. Epub 2022 Mar 10. doi: 10.2174/15665240216662108061552311566-524010.2174/1566524021666210806155231info:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:42:36Zoai:repositorio.insa.pt:10400.18/8523Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:43:09.040325Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Cell-adhesion Molecules as Key Mechanisms of Tumor Invasion:The Case of Breast Cancer
title Cell-adhesion Molecules as Key Mechanisms of Tumor Invasion:The Case of Breast Cancer
spellingShingle Cell-adhesion Molecules as Key Mechanisms of Tumor Invasion:The Case of Breast Cancer
Botelho, Mónica
Breast Cancer
Metastasis
Cell adhesion molecules
Cadherins
Selectins
Integrins
Igcam
title_short Cell-adhesion Molecules as Key Mechanisms of Tumor Invasion:The Case of Breast Cancer
title_full Cell-adhesion Molecules as Key Mechanisms of Tumor Invasion:The Case of Breast Cancer
title_fullStr Cell-adhesion Molecules as Key Mechanisms of Tumor Invasion:The Case of Breast Cancer
title_full_unstemmed Cell-adhesion Molecules as Key Mechanisms of Tumor Invasion:The Case of Breast Cancer
title_sort Cell-adhesion Molecules as Key Mechanisms of Tumor Invasion:The Case of Breast Cancer
author Botelho, Mónica
author_facet Botelho, Mónica
Luís, Carla
Soares, Raquel
Fernandes, Rúben
author_role author
author2 Luís, Carla
Soares, Raquel
Fernandes, Rúben
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Botelho, Mónica
Luís, Carla
Soares, Raquel
Fernandes, Rúben
dc.subject.por.fl_str_mv Breast Cancer
Metastasis
Cell adhesion molecules
Cadherins
Selectins
Integrins
Igcam
topic Breast Cancer
Metastasis
Cell adhesion molecules
Cadherins
Selectins
Integrins
Igcam
description Cancer is a major health problem worldwide and the second leading cause of death following cardiovascular diseases. Breast cancer is the leading cause of mortality and morbidity among women and one of the most common malignant neoplasms prompt to metastatic disease. In the present review, the mechanisms of the major cell adhesion molecules involved in tumor invasion are discussed, focusing on the case of breast cancer. A non-systematic updated revision of the literature was performed in order to assemble information regarding the expression of the adhesion cell molecules associated with metastasis.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-10
2022-03-10T00:00:00Z
2023-02-10T16:09:10Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/8523
url http://hdl.handle.net/10400.18/8523
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Curr Mol Med. 2023;23(2):147-160. Epub 2022 Mar 10. doi: 10.2174/1566524021666210806155231
1566-5240
10.2174/1566524021666210806155231
dc.rights.driver.fl_str_mv info:eu-repo/semantics/embargoedAccess
eu_rights_str_mv embargoedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Bentham Science Publishers
publisher.none.fl_str_mv Bentham Science Publishers
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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