The Role of the Cephalopod Digestive Gland in the Storage and Detoxification of Marine Pollutants

Detalhes bibliográficos
Autor(a) principal: Rodrigo, Ana P.
Data de Publicação: 2017
Outros Autores: Costa, Pedro M
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/33073
Resumo: COST Action FA1301 "A network for improvement of cephalopod welfare and husbandry in research, aquaculture and fisheries (CephsInAction)" The Portuguese Foundation for Science and Technology (FCT) MARE through the strategic programme (UID/MAR/04292/2013; SFRH/BD/109462/2015; IF/00265/2015) GreenTech (PTDC/MARBIO/0113/2014) FCT
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spelling The Role of the Cephalopod Digestive Gland in the Storage and Detoxification of Marine Pollutantsquatic toxicologymolluscaCephalopodabiomarkerstoxicological pathwaysbioaccumulationSDG 13 - Climate ActionSDG 14 - Life Below WaterCOST Action FA1301 "A network for improvement of cephalopod welfare and husbandry in research, aquaculture and fisheries (CephsInAction)" The Portuguese Foundation for Science and Technology (FCT) MARE through the strategic programme (UID/MAR/04292/2013; SFRH/BD/109462/2015; IF/00265/2015) GreenTech (PTDC/MARBIO/0113/2014) FCTThe relevance of cephalopods for fisheries and even aquaculture, is raising concerns on the relationship between these molluscs and environmental stressors, from climate change to pollution. However, how these organisms cope with environmental toxicants is far less understood than for other molluscs, especially bivalves, which are frontline models in aquatic toxicology. Although, sharing the same basic body plan, cephalopods hold distinct adaptations, often unique, as they are active predators with high growth and metabolic rates. Most studies on the digestive gland, the analog to the vertebrate liver, focused on metal bioaccumulation and its relation to environmental concentrations, with indication for the involvement of special cellular structures (like spherulae) and proteins. Although the functioning of phase I and II enzymes of detoxification in molluscs is controversial, there is evidence for CYP-mediated bioactivation, albeit with lower activity than vertebrates, but this issue needs yet much research. Through novel molecular tools, toxicology-relevant genes and proteins are being unraveled, from metallothioneins to heat-shock proteins and phase II conjugation enzymes, which highlights the importance of increasing genomic annotation as paramount to understand toxicant-specific pathways. However, little is known on how organic toxicants are stored, metabolized and eliminated, albeit some evidence from biomarker approaches, particularly those related to oxidative stress, suggesting that these molluscs' digestive gland is indeed responsive to chemical aggression. Additionally, cause-effect relationships between pollutants and toxicopathic effects are little understood, thus compromising, if not the deployment of these organisms for biomonitoring, at least understanding how they are affected by anthropogenically-induced global change.DCEA - Departamento de Ciências e Engenharia do AmbienteMARE - Centro de Ciências do Mar e do AmbienteRUNRodrigo, Ana P.Costa, Pedro M2018-03-22T23:15:18Z2017-04-202017-04-20T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/33073eng1664-042XPURE: 2750457https://doi.org/10.3389/fphys.2017.00232info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:18:19Zoai:run.unl.pt:10362/33073Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:30:00.223081Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The Role of the Cephalopod Digestive Gland in the Storage and Detoxification of Marine Pollutants
title The Role of the Cephalopod Digestive Gland in the Storage and Detoxification of Marine Pollutants
spellingShingle The Role of the Cephalopod Digestive Gland in the Storage and Detoxification of Marine Pollutants
Rodrigo, Ana P.
quatic toxicology
mollusca
Cephalopoda
biomarkers
toxicological pathways
bioaccumulation
SDG 13 - Climate Action
SDG 14 - Life Below Water
title_short The Role of the Cephalopod Digestive Gland in the Storage and Detoxification of Marine Pollutants
title_full The Role of the Cephalopod Digestive Gland in the Storage and Detoxification of Marine Pollutants
title_fullStr The Role of the Cephalopod Digestive Gland in the Storage and Detoxification of Marine Pollutants
title_full_unstemmed The Role of the Cephalopod Digestive Gland in the Storage and Detoxification of Marine Pollutants
title_sort The Role of the Cephalopod Digestive Gland in the Storage and Detoxification of Marine Pollutants
author Rodrigo, Ana P.
author_facet Rodrigo, Ana P.
Costa, Pedro M
author_role author
author2 Costa, Pedro M
author2_role author
dc.contributor.none.fl_str_mv DCEA - Departamento de Ciências e Engenharia do Ambiente
MARE - Centro de Ciências do Mar e do Ambiente
RUN
dc.contributor.author.fl_str_mv Rodrigo, Ana P.
Costa, Pedro M
dc.subject.por.fl_str_mv quatic toxicology
mollusca
Cephalopoda
biomarkers
toxicological pathways
bioaccumulation
SDG 13 - Climate Action
SDG 14 - Life Below Water
topic quatic toxicology
mollusca
Cephalopoda
biomarkers
toxicological pathways
bioaccumulation
SDG 13 - Climate Action
SDG 14 - Life Below Water
description COST Action FA1301 "A network for improvement of cephalopod welfare and husbandry in research, aquaculture and fisheries (CephsInAction)" The Portuguese Foundation for Science and Technology (FCT) MARE through the strategic programme (UID/MAR/04292/2013; SFRH/BD/109462/2015; IF/00265/2015) GreenTech (PTDC/MARBIO/0113/2014) FCT
publishDate 2017
dc.date.none.fl_str_mv 2017-04-20
2017-04-20T00:00:00Z
2018-03-22T23:15:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/33073
url http://hdl.handle.net/10362/33073
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1664-042X
PURE: 2750457
https://doi.org/10.3389/fphys.2017.00232
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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