Dietary selenium intakes and musculoskeletal function in very old adults

Detalhes bibliográficos
Autor(a) principal: Perri, Giorgia
Data de Publicação: 2020
Outros Autores: Mendonça, Nuno, Jagger, Carol, Walsh, Jennifer, Eastell, Richard, Mathers, John C., Hill, Tom R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/101655
Resumo: Funding: This individual research study received no additional funding. However, we would like to thank The MRC-Versus Arthritis Centre for Integrated Research into Musculoskeletal Ageing (CIMA) (https://www. cimauk.org/) for funding the PhD programme of study associated with this research. We would also like to acknowledge the generous donations provided by Cumbria Community Foundation and Beverley Charitable Trust Fund throughout the associated PhD programme of study.
id RCAP_32f560d0ecb773b70f7c18c873dfc7c4
oai_identifier_str oai:run.unl.pt:10362/101655
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Dietary selenium intakes and musculoskeletal function in very old adultsAnalysis of the newcastle 85+ studyDietary intakeMusculoskeletal functionNewcastle 85+ StudySeleniumVery old adultsFood ScienceNutrition and DieteticsFunding: This individual research study received no additional funding. However, we would like to thank The MRC-Versus Arthritis Centre for Integrated Research into Musculoskeletal Ageing (CIMA) (https://www. cimauk.org/) for funding the PhD programme of study associated with this research. We would also like to acknowledge the generous donations provided by Cumbria Community Foundation and Beverley Charitable Trust Fund throughout the associated PhD programme of study.Background: Selenium is a trace element essential for health. Severe selenium deficiencies are associated with poor musculoskeletal (MSK) function. However, the effects of moderate deficiency on MSK function, especially in older adults, is unclear. Objectives: To determine the associations between selenium intake and MSK function in very old adults. Methods: Selenium intake at baseline and, hand-grip strength (HGS) and timed-up-and-go (TUG) at four phases over 5 years, were available in 791 participants in the Newcastle 85+ Study, a community-based, longitudinal cohort of ≥85 year old individuals. We investigated relationships between selenium intake and HGS and TUG in cross-sectional analyses at baseline using multivariate analyses and, prospectively using linear mixed models to explore HGS and TUG changes over 5 years in association with baseline selenium intake. Results: At baseline, 53% of participants had selenium intakes that were classified as low. These individuals had 2.80 kg lower HGS and were 2.30 s slower performing the TUG, cross-sectionally. In multivariate, baseline analyses, selenium intake had no significant impact on HGS or TUG. Selenium intake had no significant effect on MSK function, prospectively. Conclusion: Low selenium intake is common among very old adults and, in cross-sectional analyses, is associated with poorer MSK function.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Comprehensive Health Research Centre (CHRC) - pólo NMSRUNPerri, GiorgiaMendonça, NunoJagger, CarolWalsh, JenniferEastell, RichardMathers, John C.Hill, Tom R.2020-07-28T22:23:56Z2020-072020-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article22application/pdfhttp://hdl.handle.net/10362/101655eng1422-8599PURE: 19236577https://doi.org/10.3390/nu12072068info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:47:55Zoai:run.unl.pt:10362/101655Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:39:36.961639Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Dietary selenium intakes and musculoskeletal function in very old adults
Analysis of the newcastle 85+ study
title Dietary selenium intakes and musculoskeletal function in very old adults
spellingShingle Dietary selenium intakes and musculoskeletal function in very old adults
Perri, Giorgia
Dietary intake
Musculoskeletal function
Newcastle 85+ Study
Selenium
Very old adults
Food Science
Nutrition and Dietetics
title_short Dietary selenium intakes and musculoskeletal function in very old adults
title_full Dietary selenium intakes and musculoskeletal function in very old adults
title_fullStr Dietary selenium intakes and musculoskeletal function in very old adults
title_full_unstemmed Dietary selenium intakes and musculoskeletal function in very old adults
title_sort Dietary selenium intakes and musculoskeletal function in very old adults
author Perri, Giorgia
author_facet Perri, Giorgia
Mendonça, Nuno
Jagger, Carol
Walsh, Jennifer
Eastell, Richard
Mathers, John C.
Hill, Tom R.
author_role author
author2 Mendonça, Nuno
Jagger, Carol
Walsh, Jennifer
Eastell, Richard
Mathers, John C.
Hill, Tom R.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
Comprehensive Health Research Centre (CHRC) - pólo NMS
RUN
dc.contributor.author.fl_str_mv Perri, Giorgia
Mendonça, Nuno
Jagger, Carol
Walsh, Jennifer
Eastell, Richard
Mathers, John C.
Hill, Tom R.
dc.subject.por.fl_str_mv Dietary intake
Musculoskeletal function
Newcastle 85+ Study
Selenium
Very old adults
Food Science
Nutrition and Dietetics
topic Dietary intake
Musculoskeletal function
Newcastle 85+ Study
Selenium
Very old adults
Food Science
Nutrition and Dietetics
description Funding: This individual research study received no additional funding. However, we would like to thank The MRC-Versus Arthritis Centre for Integrated Research into Musculoskeletal Ageing (CIMA) (https://www. cimauk.org/) for funding the PhD programme of study associated with this research. We would also like to acknowledge the generous donations provided by Cumbria Community Foundation and Beverley Charitable Trust Fund throughout the associated PhD programme of study.
publishDate 2020
dc.date.none.fl_str_mv 2020-07-28T22:23:56Z
2020-07
2020-07-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/101655
url http://hdl.handle.net/10362/101655
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1422-8599
PURE: 19236577
https://doi.org/10.3390/nu12072068
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 22
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799138012624322560

Registros relacionados