IL10 Low-Frequency Variants in Behçet's Disease Patients
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/2548 |
Resumo: | To explain the missing heritability after the genome-wide association studies era, sequencing studies allow the identification of low-frequency variants with a stronger effect on disease risk. Common variants in the interleukin 10 gene (IL10) have been consistently associated with Behçet's disease (BD) and the goal of this study is to investigate the role of low-frequency IL10 variants in BD susceptibility. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
spelling |
IL10 Low-Frequency Variants in Behçet's Disease PatientsBehçet's diseaseIL10Low-frequency variantsHCC DAUTOIMTo explain the missing heritability after the genome-wide association studies era, sequencing studies allow the identification of low-frequency variants with a stronger effect on disease risk. Common variants in the interleukin 10 gene (IL10) have been consistently associated with Behçet's disease (BD) and the goal of this study is to investigate the role of low-frequency IL10 variants in BD susceptibility.Wiley PublishingRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEMatos, MXavier, JMAbrantes, PSousa, IRei, NDavatchi, FShahram, FJesus, GBarcelos, FVedes, JSalgado, ManuelAbdollahi, BNadji, AMoraes-Fontes, MFShafiee, NGhaderibarmi, FVaz Patto, JCrespo, JOliveira, SA2016-08-11T10:30:30Z2014-04-082014-04-08T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/2548engInt J Rheum Dis. 2014 Apr 8.10.1111/1756-185X.12369info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-10-28T10:27:46Zoai:repositorio.chlc.pt:10400.17/2548Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-10-28T10:27:46Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
IL10 Low-Frequency Variants in Behçet's Disease Patients |
title |
IL10 Low-Frequency Variants in Behçet's Disease Patients |
spellingShingle |
IL10 Low-Frequency Variants in Behçet's Disease Patients Matos, M Behçet's disease IL10 Low-frequency variants HCC DAUTOIM |
title_short |
IL10 Low-Frequency Variants in Behçet's Disease Patients |
title_full |
IL10 Low-Frequency Variants in Behçet's Disease Patients |
title_fullStr |
IL10 Low-Frequency Variants in Behçet's Disease Patients |
title_full_unstemmed |
IL10 Low-Frequency Variants in Behçet's Disease Patients |
title_sort |
IL10 Low-Frequency Variants in Behçet's Disease Patients |
author |
Matos, M |
author_facet |
Matos, M Xavier, JM Abrantes, P Sousa, I Rei, N Davatchi, F Shahram, F Jesus, G Barcelos, F Vedes, J Salgado, Manuel Abdollahi, B Nadji, A Moraes-Fontes, MF Shafiee, N Ghaderibarmi, F Vaz Patto, J Crespo, J Oliveira, SA |
author_role |
author |
author2 |
Xavier, JM Abrantes, P Sousa, I Rei, N Davatchi, F Shahram, F Jesus, G Barcelos, F Vedes, J Salgado, Manuel Abdollahi, B Nadji, A Moraes-Fontes, MF Shafiee, N Ghaderibarmi, F Vaz Patto, J Crespo, J Oliveira, SA |
author2_role |
author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Matos, M Xavier, JM Abrantes, P Sousa, I Rei, N Davatchi, F Shahram, F Jesus, G Barcelos, F Vedes, J Salgado, Manuel Abdollahi, B Nadji, A Moraes-Fontes, MF Shafiee, N Ghaderibarmi, F Vaz Patto, J Crespo, J Oliveira, SA |
dc.subject.por.fl_str_mv |
Behçet's disease IL10 Low-frequency variants HCC DAUTOIM |
topic |
Behçet's disease IL10 Low-frequency variants HCC DAUTOIM |
description |
To explain the missing heritability after the genome-wide association studies era, sequencing studies allow the identification of low-frequency variants with a stronger effect on disease risk. Common variants in the interleukin 10 gene (IL10) have been consistently associated with Behçet's disease (BD) and the goal of this study is to investigate the role of low-frequency IL10 variants in BD susceptibility. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-04-08 2014-04-08T00:00:00Z 2016-08-11T10:30:30Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/2548 |
url |
http://hdl.handle.net/10400.17/2548 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Int J Rheum Dis. 2014 Apr 8. 10.1111/1756-185X.12369 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley Publishing |
publisher.none.fl_str_mv |
Wiley Publishing |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
mluisa.alvim@gmail.com |
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1817548645754470400 |