IL10 Low-Frequency Variants in Behçet's Disease Patients

Detalhes bibliográficos
Autor(a) principal: Matos, M
Data de Publicação: 2014
Outros Autores: Xavier, JM, Abrantes, P, Sousa, I, Rei, N, Davatchi, F, Shahram, F, Jesus, G, Barcelos, F, Vedes, J, Salgado, Manuel, Abdollahi, B, Nadji, A, Moraes-Fontes, MF, Shafiee, N, Ghaderibarmi, F, Vaz Patto, J, Crespo, J, Oliveira, SA
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.17/2548
Resumo: To explain the missing heritability after the genome-wide association studies era, sequencing studies allow the identification of low-frequency variants with a stronger effect on disease risk. Common variants in the interleukin 10 gene (IL10) have been consistently associated with Behçet's disease (BD) and the goal of this study is to investigate the role of low-frequency IL10 variants in BD susceptibility.
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spelling IL10 Low-Frequency Variants in Behçet's Disease PatientsBehçet's diseaseIL10Low-frequency variantsHCC DAUTOIMTo explain the missing heritability after the genome-wide association studies era, sequencing studies allow the identification of low-frequency variants with a stronger effect on disease risk. Common variants in the interleukin 10 gene (IL10) have been consistently associated with Behçet's disease (BD) and the goal of this study is to investigate the role of low-frequency IL10 variants in BD susceptibility.Wiley PublishingRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEMatos, MXavier, JMAbrantes, PSousa, IRei, NDavatchi, FShahram, FJesus, GBarcelos, FVedes, JSalgado, ManuelAbdollahi, BNadji, AMoraes-Fontes, MFShafiee, NGhaderibarmi, FVaz Patto, JCrespo, JOliveira, SA2016-08-11T10:30:30Z2014-04-082014-04-08T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/2548engInt J Rheum Dis. 2014 Apr 8.10.1111/1756-185X.12369info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:38:16ZPortal AgregadorONG
dc.title.none.fl_str_mv IL10 Low-Frequency Variants in Behçet's Disease Patients
title IL10 Low-Frequency Variants in Behçet's Disease Patients
spellingShingle IL10 Low-Frequency Variants in Behçet's Disease Patients
Matos, M
Behçet's disease
IL10
Low-frequency variants
HCC DAUTOIM
title_short IL10 Low-Frequency Variants in Behçet's Disease Patients
title_full IL10 Low-Frequency Variants in Behçet's Disease Patients
title_fullStr IL10 Low-Frequency Variants in Behçet's Disease Patients
title_full_unstemmed IL10 Low-Frequency Variants in Behçet's Disease Patients
title_sort IL10 Low-Frequency Variants in Behçet's Disease Patients
author Matos, M
author_facet Matos, M
Xavier, JM
Abrantes, P
Sousa, I
Rei, N
Davatchi, F
Shahram, F
Jesus, G
Barcelos, F
Vedes, J
Salgado, Manuel
Abdollahi, B
Nadji, A
Moraes-Fontes, MF
Shafiee, N
Ghaderibarmi, F
Vaz Patto, J
Crespo, J
Oliveira, SA
author_role author
author2 Xavier, JM
Abrantes, P
Sousa, I
Rei, N
Davatchi, F
Shahram, F
Jesus, G
Barcelos, F
Vedes, J
Salgado, Manuel
Abdollahi, B
Nadji, A
Moraes-Fontes, MF
Shafiee, N
Ghaderibarmi, F
Vaz Patto, J
Crespo, J
Oliveira, SA
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE
dc.contributor.author.fl_str_mv Matos, M
Xavier, JM
Abrantes, P
Sousa, I
Rei, N
Davatchi, F
Shahram, F
Jesus, G
Barcelos, F
Vedes, J
Salgado, Manuel
Abdollahi, B
Nadji, A
Moraes-Fontes, MF
Shafiee, N
Ghaderibarmi, F
Vaz Patto, J
Crespo, J
Oliveira, SA
dc.subject.por.fl_str_mv Behçet's disease
IL10
Low-frequency variants
HCC DAUTOIM
topic Behçet's disease
IL10
Low-frequency variants
HCC DAUTOIM
description To explain the missing heritability after the genome-wide association studies era, sequencing studies allow the identification of low-frequency variants with a stronger effect on disease risk. Common variants in the interleukin 10 gene (IL10) have been consistently associated with Behçet's disease (BD) and the goal of this study is to investigate the role of low-frequency IL10 variants in BD susceptibility.
publishDate 2014
dc.date.none.fl_str_mv 2014-04-08
2014-04-08T00:00:00Z
2016-08-11T10:30:30Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.17/2548
url http://hdl.handle.net/10400.17/2548
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Int J Rheum Dis. 2014 Apr 8.
10.1111/1756-185X.12369
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley Publishing
publisher.none.fl_str_mv Wiley Publishing
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv
repository.mail.fl_str_mv
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