Comparison of 5 acute pulmonary embolism mortality risk scores in patients with COVID-19

Detalhes bibliográficos
Autor(a) principal: Rodrigues, Tiago
Data de Publicação: 2022
Outros Autores: Valente Silva, Beatriz, Plácido, Rui, Mendonça, Carlos, Urbano, Maria Luísa, Rigueira, Joana, Almeida, Ana G., Pinto, Fausto J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/51897
Resumo: © The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
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spelling Comparison of 5 acute pulmonary embolism mortality risk scores in patients with COVID-19CoronavirusMortality risk scoresPrognostic factorsPulmonary embolismSARS-CoV-2 infection© The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)Objective: Pulmonary embolism (PE) is a common complication of SARS-CoV-2 infection. We aimed to explore the short-term outcomes among patients with acute PE and COVID-19 and to further determine and compare the performance of the different prognostic scores (PESI, sPESI, BOVA, FAST and ESC scores) for risk-stratification in this scenario. Methods: Retrospective single-centre study of 85 patients with SARS-CoV-2 infection and PE admitted to the Emergency Department (ED). The diagnostic accuracy of each above-mentioned prognostic score was calculated post hoc, and their discriminative power was evaluated through an AUC curve. Results: Among the 85 patients, all-cause death occurred within 7 days for 6 patients (7.1%) and within 30 days for 14 patients (16.5%). Despite being older and having a higher percentage of altered mental status on presentation, non-survivors patients did not differ from survivors regarding comorbidities, traditional risk factors for venous thromboembolism and signs and symptoms at the ED presentation.Each risk stratification tool had modest discriminative power for 7-day mortality (AUC range, 0.601-0.730) with slightly lower discrimination for 30-day mortality (AUC range, 0.543-0.638). The pair-wise comparison of ROC curves showed that PESI had better predictive value for short-term mortality than ESC score (z test = 3.92, p = 0.001) and sPESI (z test = 2.43, p = 0.015); there is no significant difference between PESI and BOVA score (z test = 1.05, p = 0.295) and FAST score (z test = 0.986, p = 0.324). Conclusion: The most common risk-stratification tools for PE had modest discriminative power to predict short-term mortality in patients with acute PE and COVID-19.ElsevierRepositório da Universidade de LisboaRodrigues, TiagoValente Silva, BeatrizPlácido, RuiMendonça, CarlosUrbano, Maria LuísaRigueira, JoanaAlmeida, Ana G.Pinto, Fausto J.2022-03-22T16:18:31Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/51897engInt J Cardiol Heart Vasc. 2022 Apr;39:10098410.1016/j.ijcha.2022.1009842352-9067info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:56:53Zoai:repositorio.ul.pt:10451/51897Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:03:06.150254Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Comparison of 5 acute pulmonary embolism mortality risk scores in patients with COVID-19
title Comparison of 5 acute pulmonary embolism mortality risk scores in patients with COVID-19
spellingShingle Comparison of 5 acute pulmonary embolism mortality risk scores in patients with COVID-19
Rodrigues, Tiago
Coronavirus
Mortality risk scores
Prognostic factors
Pulmonary embolism
SARS-CoV-2 infection
title_short Comparison of 5 acute pulmonary embolism mortality risk scores in patients with COVID-19
title_full Comparison of 5 acute pulmonary embolism mortality risk scores in patients with COVID-19
title_fullStr Comparison of 5 acute pulmonary embolism mortality risk scores in patients with COVID-19
title_full_unstemmed Comparison of 5 acute pulmonary embolism mortality risk scores in patients with COVID-19
title_sort Comparison of 5 acute pulmonary embolism mortality risk scores in patients with COVID-19
author Rodrigues, Tiago
author_facet Rodrigues, Tiago
Valente Silva, Beatriz
Plácido, Rui
Mendonça, Carlos
Urbano, Maria Luísa
Rigueira, Joana
Almeida, Ana G.
Pinto, Fausto J.
author_role author
author2 Valente Silva, Beatriz
Plácido, Rui
Mendonça, Carlos
Urbano, Maria Luísa
Rigueira, Joana
Almeida, Ana G.
Pinto, Fausto J.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Rodrigues, Tiago
Valente Silva, Beatriz
Plácido, Rui
Mendonça, Carlos
Urbano, Maria Luísa
Rigueira, Joana
Almeida, Ana G.
Pinto, Fausto J.
dc.subject.por.fl_str_mv Coronavirus
Mortality risk scores
Prognostic factors
Pulmonary embolism
SARS-CoV-2 infection
topic Coronavirus
Mortality risk scores
Prognostic factors
Pulmonary embolism
SARS-CoV-2 infection
description © The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
publishDate 2022
dc.date.none.fl_str_mv 2022-03-22T16:18:31Z
2022
2022-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/51897
url http://hdl.handle.net/10451/51897
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Int J Cardiol Heart Vasc. 2022 Apr;39:100984
10.1016/j.ijcha.2022.100984
2352-9067
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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