Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture

Detalhes bibliográficos
Autor(a) principal: Miranda, Catarina S.
Data de Publicação: 2022
Outros Autores: Silva, Ana Francisca G., Pereira-Lima, Sílvia M. M. A., Costa, Susana P. G., Homem, Natália Cândido, Felgueiras, Helena Prado
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/75742
Resumo: Electrospinning and wet-spinning have been recognized as two of the most efficient and promising techniques for producing polymeric fibrous constructs for a wide range of applications, including optics, electronics, food industry and biomedical applications. They have gained considerable attention in the past few decades because of their unique features and tunable architectures that can mimic desirable biological features, responding more effectively to local demands. In this review, various fiber architectures and configurations, varying from monolayer and core-shell fibers to tri-axial, porous, multilayer, side-by-side and helical fibers, are discussed, highlighting the influence of processing parameters in the final constructs. Additionally, the envisaged biomedical purposes for the examined fiber architectures, mainly focused on drug delivery and tissue engineering applications, are explored at great length.
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spelling Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architectureDrug deliveryElectrospinningFiber architecturesFibrous constructsTissue engineeringWet-spinningEngenharia e Tecnologia::Engenharia dos MateriaisScience & TechnologyElectrospinning and wet-spinning have been recognized as two of the most efficient and promising techniques for producing polymeric fibrous constructs for a wide range of applications, including optics, electronics, food industry and biomedical applications. They have gained considerable attention in the past few decades because of their unique features and tunable architectures that can mimic desirable biological features, responding more effectively to local demands. In this review, various fiber architectures and configurations, varying from monolayer and core-shell fibers to tri-axial, porous, multilayer, side-by-side and helical fibers, are discussed, highlighting the influence of processing parameters in the final constructs. Additionally, the envisaged biomedical purposes for the examined fiber architectures, mainly focused on drug delivery and tissue engineering applications, are explored at great length.Authors acknowledge the Portuguese Foundation for Science and Technol ogy (FCT), FEDER funds by means of Portugal 2020 Competitive Factors Operational Program (POCI) and the Portuguese Government (OE) for funding the project PEPTEX with reference PTDC/CTMTEX/28074/2017 (POCI-01-0145-FEDER-028074). Authors also acknowledge project UID/CTM/00264/2020 of 2C2T and UID/QUI/00686/2020 of CQ, funded by national funds through FCT/MCTES. C.S.M. acknowledges FCT for PhD funding via scholarship 2020.08547.BD.MDPIUniversidade do MinhoMiranda, Catarina S.Silva, Ana Francisca G.Pereira-Lima, Sílvia M. M. A.Costa, Susana P. G.Homem, Natália CândidoFelgueiras, Helena Prado2022-01-112022-01-11T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/75742eng1999-492310.3390/pharmaceutics14010164https://www.mdpi.com/1999-4923/14/1/164info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:38:02Zoai:repositorium.sdum.uminho.pt:1822/75742Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:34:23.508341Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture
title Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture
spellingShingle Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture
Miranda, Catarina S.
Drug delivery
Electrospinning
Fiber architectures
Fibrous constructs
Tissue engineering
Wet-spinning
Engenharia e Tecnologia::Engenharia dos Materiais
Science & Technology
title_short Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture
title_full Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture
title_fullStr Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture
title_full_unstemmed Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture
title_sort Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture
author Miranda, Catarina S.
author_facet Miranda, Catarina S.
Silva, Ana Francisca G.
Pereira-Lima, Sílvia M. M. A.
Costa, Susana P. G.
Homem, Natália Cândido
Felgueiras, Helena Prado
author_role author
author2 Silva, Ana Francisca G.
Pereira-Lima, Sílvia M. M. A.
Costa, Susana P. G.
Homem, Natália Cândido
Felgueiras, Helena Prado
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Miranda, Catarina S.
Silva, Ana Francisca G.
Pereira-Lima, Sílvia M. M. A.
Costa, Susana P. G.
Homem, Natália Cândido
Felgueiras, Helena Prado
dc.subject.por.fl_str_mv Drug delivery
Electrospinning
Fiber architectures
Fibrous constructs
Tissue engineering
Wet-spinning
Engenharia e Tecnologia::Engenharia dos Materiais
Science & Technology
topic Drug delivery
Electrospinning
Fiber architectures
Fibrous constructs
Tissue engineering
Wet-spinning
Engenharia e Tecnologia::Engenharia dos Materiais
Science & Technology
description Electrospinning and wet-spinning have been recognized as two of the most efficient and promising techniques for producing polymeric fibrous constructs for a wide range of applications, including optics, electronics, food industry and biomedical applications. They have gained considerable attention in the past few decades because of their unique features and tunable architectures that can mimic desirable biological features, responding more effectively to local demands. In this review, various fiber architectures and configurations, varying from monolayer and core-shell fibers to tri-axial, porous, multilayer, side-by-side and helical fibers, are discussed, highlighting the influence of processing parameters in the final constructs. Additionally, the envisaged biomedical purposes for the examined fiber architectures, mainly focused on drug delivery and tissue engineering applications, are explored at great length.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-11
2022-01-11T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/75742
url http://hdl.handle.net/1822/75742
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1999-4923
10.3390/pharmaceutics14010164
https://www.mdpi.com/1999-4923/14/1/164
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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