Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/75742 |
Resumo: | Electrospinning and wet-spinning have been recognized as two of the most efficient and promising techniques for producing polymeric fibrous constructs for a wide range of applications, including optics, electronics, food industry and biomedical applications. They have gained considerable attention in the past few decades because of their unique features and tunable architectures that can mimic desirable biological features, responding more effectively to local demands. In this review, various fiber architectures and configurations, varying from monolayer and core-shell fibers to tri-axial, porous, multilayer, side-by-side and helical fibers, are discussed, highlighting the influence of processing parameters in the final constructs. Additionally, the envisaged biomedical purposes for the examined fiber architectures, mainly focused on drug delivery and tissue engineering applications, are explored at great length. |
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Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architectureDrug deliveryElectrospinningFiber architecturesFibrous constructsTissue engineeringWet-spinningEngenharia e Tecnologia::Engenharia dos MateriaisScience & TechnologyElectrospinning and wet-spinning have been recognized as two of the most efficient and promising techniques for producing polymeric fibrous constructs for a wide range of applications, including optics, electronics, food industry and biomedical applications. They have gained considerable attention in the past few decades because of their unique features and tunable architectures that can mimic desirable biological features, responding more effectively to local demands. In this review, various fiber architectures and configurations, varying from monolayer and core-shell fibers to tri-axial, porous, multilayer, side-by-side and helical fibers, are discussed, highlighting the influence of processing parameters in the final constructs. Additionally, the envisaged biomedical purposes for the examined fiber architectures, mainly focused on drug delivery and tissue engineering applications, are explored at great length.Authors acknowledge the Portuguese Foundation for Science and Technol ogy (FCT), FEDER funds by means of Portugal 2020 Competitive Factors Operational Program (POCI) and the Portuguese Government (OE) for funding the project PEPTEX with reference PTDC/CTMTEX/28074/2017 (POCI-01-0145-FEDER-028074). Authors also acknowledge project UID/CTM/00264/2020 of 2C2T and UID/QUI/00686/2020 of CQ, funded by national funds through FCT/MCTES. C.S.M. acknowledges FCT for PhD funding via scholarship 2020.08547.BD.MDPIUniversidade do MinhoMiranda, Catarina S.Silva, Ana Francisca G.Pereira-Lima, Sílvia M. M. A.Costa, Susana P. G.Homem, Natália CândidoFelgueiras, Helena Prado2022-01-112022-01-11T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/75742eng1999-492310.3390/pharmaceutics14010164https://www.mdpi.com/1999-4923/14/1/164info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:38:02Zoai:repositorium.sdum.uminho.pt:1822/75742Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:34:23.508341Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture |
title |
Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture |
spellingShingle |
Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture Miranda, Catarina S. Drug delivery Electrospinning Fiber architectures Fibrous constructs Tissue engineering Wet-spinning Engenharia e Tecnologia::Engenharia dos Materiais Science & Technology |
title_short |
Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture |
title_full |
Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture |
title_fullStr |
Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture |
title_full_unstemmed |
Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture |
title_sort |
Tunable spun fiber constructs in biomedicine: influence of processing parameters in the fibers' architecture |
author |
Miranda, Catarina S. |
author_facet |
Miranda, Catarina S. Silva, Ana Francisca G. Pereira-Lima, Sílvia M. M. A. Costa, Susana P. G. Homem, Natália Cândido Felgueiras, Helena Prado |
author_role |
author |
author2 |
Silva, Ana Francisca G. Pereira-Lima, Sílvia M. M. A. Costa, Susana P. G. Homem, Natália Cândido Felgueiras, Helena Prado |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Miranda, Catarina S. Silva, Ana Francisca G. Pereira-Lima, Sílvia M. M. A. Costa, Susana P. G. Homem, Natália Cândido Felgueiras, Helena Prado |
dc.subject.por.fl_str_mv |
Drug delivery Electrospinning Fiber architectures Fibrous constructs Tissue engineering Wet-spinning Engenharia e Tecnologia::Engenharia dos Materiais Science & Technology |
topic |
Drug delivery Electrospinning Fiber architectures Fibrous constructs Tissue engineering Wet-spinning Engenharia e Tecnologia::Engenharia dos Materiais Science & Technology |
description |
Electrospinning and wet-spinning have been recognized as two of the most efficient and promising techniques for producing polymeric fibrous constructs for a wide range of applications, including optics, electronics, food industry and biomedical applications. They have gained considerable attention in the past few decades because of their unique features and tunable architectures that can mimic desirable biological features, responding more effectively to local demands. In this review, various fiber architectures and configurations, varying from monolayer and core-shell fibers to tri-axial, porous, multilayer, side-by-side and helical fibers, are discussed, highlighting the influence of processing parameters in the final constructs. Additionally, the envisaged biomedical purposes for the examined fiber architectures, mainly focused on drug delivery and tissue engineering applications, are explored at great length. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-11 2022-01-11T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/75742 |
url |
http://hdl.handle.net/1822/75742 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1999-4923 10.3390/pharmaceutics14010164 https://www.mdpi.com/1999-4923/14/1/164 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799132865433174016 |